High Potency Biotin 2500 mcg Ingredients & Drug Interactions
by Nature Made
What is this page for?
First and foremost: checking High Potency Biotin 2500 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
High Potency Biotin 2500 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of High Potency Biotin 2500 mcg by Nature Made
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: biotin, a B vitamin at a 2500 mcg dose per softgel. Biotin is a water-soluble vitamin that your body doesn't store, so excess amounts leave through your urine.
The softgels also contain inactive ingredients — soybean oil, gelatin, glycerin, yellow beeswax, water, soy lecithin, and added colors — that form the capsule and help deliver the biotin.
Does it work?
Strong evidence
Biotin is likely effective for biotin deficiency — a real but uncommon shortage of this B vitamin. For other uses listed here, the evidence is weaker: it's considered possibly ineffective for multiple sclerosis and seborrheic dermatitis (a skin condition that causes flaking and inflammation), and there isn't enough reliable evidence to rate it for alopecia areata (patchy hair loss).
How safe is it?
Well-documented data
Biotin is generally well tolerated, even at fairly high doses, because your body excretes excess amounts in your urine. High-dose biotin has rarely been linked to mild diarrhea — a small number of people taking very large amounts (like 300 mg daily, far above this 2500 mcg dose) reported it.
One isolated case report described an inflammatory reaction in a 76-year-old woman taking biotin along with other supplements and a heart medication, but it's unclear whether biotin was the cause. The safety data rates biotin as likely safe during pregnancy and lactation at normal dietary and supplement amounts.
Because this is a high-dose product, check with your doctor before taking it if you're pregnant or nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for biotin. That's worth knowing, but always check your specific medications in the search tool below — no documented interactions is not a guarantee none exist.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This biotin supplement makes sense if you have a documented biotin deficiency or want to try it for hair, skin, or nails — though evidence for those last two is limited. If you're pregnant, nursing, or taking any medications, talk with your doctor first, especially since this is a high-dose product.
Run your full medication list through the checker on this page to be sure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about High Potency Biotin 2500 mcg, straight from the product label.
| Brand | Nature Made |
|---|---|
| Barcode (UPC) | 031604425463 |
| Net contents | 90 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Aug 31, 2018 |
| DSLD ID | 179651 |
| Product type | Vitamin |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for High Potency Biotin 2500 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Biotin | 2500 mcg | 833% |
Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Soy Lecithin, Colors added
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
#1 pharmacist recommended High potency
May help support healthy hair, skin & nails
Biotin may help support healthy hair, skin and nails in those that are biotin deficient. Biotin also supports carbohydrate, protein & fat metabolism.
USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.
Seals/Symbols
USP Dietary Supplement Verified
FDA Statement of Identity
Dietary Supplement
Formulation
Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free
Suggested/Recommended/Usage/Directions
Suggested use: Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.
Storage
Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.
Precautions
Store in a cool, dry place, out of reach of children.
Do not use if imprinted seal under cap is broken or missing.
Contains: Soy.
Formula
Contains: Soy.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
List No. 2546Z L201 Cat. A521 5A002
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
High Potency Biotin 2500 mcg by Nature Made label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in High Potency Biotin 2500 mcg by Nature Made
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Biotin
No knowninteractions
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...
Biotin monograph & interactionsOther (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Soy Lecithin, Colors added. These complete the product’s ingredient list but are not active constituents.
High Potency Biotin 2500 mcg by Nature Made Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in High Potency Biotin 2500 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for High Potency Biotin 2500 mcg, from the product label.
Nature Made
See all Nature Made products- Name
- Nature Made Nutritional Products
- City
- Mission Hills
- State
- CA
- ZipCode
- 91346-9606
- Phone Number
- 1-800-276-2878
- Web Address
- www.NatureMade.com
High Potency Biotin 2500 mcg by Nature Made: Common Questions
Does High Potency Biotin 2500 mcg by Nature Made interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this biotin supplement help my hair or nails grow?
Is biotin safe to take every day?
Can I take this while pregnant or breastfeeding?
What is biotin, and what does it do?
Does this softgel contain any allergens?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if High Potency Biotin 2500 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind High Potency Biotin 2500 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
High Potency Biotin 2500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Biotin 4 references
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
- Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC