High Potency Pantothenic Acid 500 mg Ingredients & Drug Interactions
by Natures Plus
What is this page for?
First and foremost: checking High Potency Pantothenic Acid 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
High Potency Pantothenic Acid 500 mg is a dietary supplement by Natures Plus with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of High Potency Pantothenic Acid 500 mg by Natures Plus
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: pantothenic acid at 500 mg per dose. Pantothenic acid is a B vitamin (also called vitamin B5) that your body needs to break down fats and carbohydrates and to make certain hormones and cholesterol.
The tablet also contains several inactive ingredients — microcrystalline cellulose, vegetable cellulose, stearic acid, magnesium stearate, rice bran, pharmaceutical glaze, and silica — that serve as binders, fillers, and coatings to hold the tablet together and make it easier to swallow.
Does it work?
Strong evidence
Pantothenic acid is effective for treating pantothenic acid deficiency — a genuine shortage of this B vitamin in your body, though it's rare. For other uses, the evidence is much weaker.
It's rated possibly ineffective for radiation dermatitis (skin damage from radiation therapy), and there's insufficient reliable evidence to rate it for hay fever, alcoholism, or hair loss (alopecia areata). If you're considering this supplement for one of those other conditions, talk with your doctor first about whether the evidence supports it for your situation.
How safe is it?
Well-documented data
Orally, pantothenic acid is generally well tolerated at typical supplement doses. The most common side effect reported is diarrhea.
Most people don't experience problems at standard doses, but because this is a high-potency formulation at 500 mg, the facts advise checking with your doctor before taking high-dose supplements — amounts in food and prenatal vitamins are fine, but a product this concentrated warrants a quick conversation with your healthcare provider first. Pantothenic acid is rated Likely Safe in pregnancy and lactation, so amounts used in prenatal vitamins and normal dietary intake are appropriate during those times.
Meds to double-check
No known interactions
No interactions are documented in our data for pantothenic acid.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you have a documented pantothenic acid deficiency, this high-potency tablet may help. For other uses like hay fever or hair loss, the evidence isn't there yet.
Because this is a high-dose supplement, check with your doctor or pharmacist before you start — especially if you're pregnant, breastfeeding, or have any health concerns. No interactions are documented, but that's not a substitute for confirming with your own healthcare provider that it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about High Potency Pantothenic Acid 500 mg, straight from the product label.
| Brand | Natures Plus |
|---|---|
| Barcode (UPC) | 097467020306 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2019 |
| DSLD ID | 188901 |
| Product type | Vitamin |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for High Potency Pantothenic Acid 500 mg by Natures Plus, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pantothenic Acid | 500 mg | 5000% |
Other ingredients: Microcrystalline Cellulose, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Rice Bran, Pharmaceutical Glaze, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Nutritional Support for Natural Energy Production.
Formulation
Free from the artificial colors and preservatives. Free from the common allergens yeast, wheat, corn, soy and milk.
Vegetarian
Hypo-Allergenic
Gluten free
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, one tablet daily before or after a meal.
Storage
Keep tightly closed in a cool, dry place.
Precautions
Keep out of reach of children.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
PRODUCT NO. 2030 LBL. 1136499
Formula
High Potency Pantothenic Acid 500 mg
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Gluten free
Quality Natural Supplements
Vegetarian
Brand IP Statement(s)
Natural Organics
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
High Potency Pantothenic Acid 500 mg by Natures Plus label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in High Potency Pantothenic Acid 500 mg by Natures Plus
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
Pantothenic Acid
No knowninteractions
Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...
Pantothenic Acid monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Rice Bran, Pharmaceutical Glaze, Silica. These complete the product’s ingredient list but are not active constituents.
High Potency Pantothenic Acid 500 mg by Natures Plus Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in High Potency Pantothenic Acid 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for High Potency Pantothenic Acid 500 mg, from the product label.
Natures Plus
See all Natures Plus products- Name
- Natural Organics Laboratories, Inc. makers of Nature's Plus
- Street Address
- 9500 New Horizons Blvd.
- City
- Amityville
- State
- New York
- ZipCode
- 11701
- Web Address
- www.naturesplus.com
High Potency Pantothenic Acid 500 mg by Natures Plus: Common Questions
Does High Potency Pantothenic Acid 500 mg by Natures Plus interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does pantothenic acid do in my body?
Is this safe to take if I'm pregnant or breastfeeding?
Will this help my hair loss?
What side effects might I experience?
Why do I need to check with my doctor if there are no drug interactions?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if High Potency Pantothenic Acid 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind High Potency Pantothenic Acid 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
High Potency Pantothenic Acid 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pantothenic Acid 11 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
- Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
- Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
- Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
- Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
- Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
- Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
- Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC