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Dietary supplement

Holy Basil Ingredients & Drug Interactions

by Oregon's Wild Harvest

Holy Basil label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Holy Basil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Holy Basil is a dietary supplement by Oregon's Wild Harvest with 1 active ingredient. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Holy Basil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Holy Basil by Oregon's Wild Harvest

Ask about any prescription or over-the-counter medication and we check it for interactions with Holy Basil by Oregon's Wild Harvest — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Holy Basil by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: holy basil. That's it for actives.

The only other ingredient listed is pullulan, which is an inactive ingredient (a binder used to make the capsule). So you're getting holy basil extract in capsule form with minimal added ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Holy Basil product and its label doesn't state a use — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows insufficient reliable evidence to rate holy basil for any of the conditions it's traditionally used for—generalized anxiety, asthma, headache, respiratory infections, dental plaque, or diabetes. That doesn't mean it doesn't work; it means the evidence available isn't solid enough to establish whether it does.

If you're considering it for one of these reasons, talk with your pharmacist about what the research actually shows.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil is generally well tolerated in the short term, though long-term safety data in humans are limited. The most common side effects from oral use are loose stools and nausea—a small number of people in clinical trials experienced these.

During pregnancy, the safety data advises against it; animal studies raise concerns and human safety is not established. While breastfeeding, there isn't enough reliable safety information, so it's best to avoid it then too.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this product, double-check with your pharmacist if you take blood thinners or antiplatelet drugs—there's a moderate risk of increased bleeding. Also flag it if you're on diabetes medications (moderate risk of blood sugar dropping too low) or pentobarbital (moderate risk of increased drowsiness).

These are the medication types documented to interact with holy basil.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Holy Basil from Oregon's Wild Harvest may be worth considering if you're interested in its traditional uses, but the evidence for effectiveness isn't established yet. If you take blood thinners, diabetes medications, or pentobarbital, check with your pharmacist first—those are the interactions that matter most.

And skip it if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holy Basil, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195004112
Net contents 60 Organic Vegan Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 331503
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holy Basil by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
706195004112
IngredientAmount% DV
Holy Basil800 mg--

Other ingredients: Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Organic to our roots

Actual size

Formulation

As certified organic farmers since 1994, our regenerative practices heal the land and water and sequester carbon from the atmosphere, while ensuring that pure, potent herbal medicine is available today and for future generations. Peace.

Free from: Gluten, dairy and soy allergens.

Organic USDA Organic

Supports a positive & balanced stress response

Verified non-GMO Product verified non-GMO by SGS.

Precautions

Caution: Keep out of reach of children.

If taking medication consult with a healthcare professional before use. Do not take if pregnant or nursing.

Discontinue use if unusual symptoms occur.

Do not exceed recommended dose.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Oregon's Wild Harvest Herbal Supplement Family Farm Since 1994

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Verified non-GMO USDA Organic OTCO Oregon Tilth Certified Organic Certified Organic by Oregon Tilth

OTCO Oregon Tilth Certified Organic Certified Organic by Oregon Tilth

Suggested/Recommended/Usage/Directions

Suggested Use: As an herbal supplement, take one capsule two times per day or as directed by your healthcare professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Holy Basil by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Holy Basil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Holy Basil by Oregon's Wild Harvest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Holy Basil

Interacts with
212 drugs
800 mg per serving Form: Ocimum sanctum

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil monograph & interactions

Other (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holy Basil by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against Holy Basil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Holy Basil 212

Individual Drug Interactions

The ingredients in Holy Basil interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in Holy Basil interact with drugs. Each result below shows which ingredient is responsible. Holy Basil

Each ingredient & the kinds of drugs it affects

For each ingredient in Holy Basil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Holy Basil3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Holy Basil, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
City
Redmond
State
OR
ZipCode
97756
Phone Number
800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

Holy Basil by Oregon's Wild Harvest: Common Questions

Does Holy Basil by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, Holy Basil has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Holy Basil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What actually is holy basil, and is it the same as the basil in cooking?
Holy basil is a plant extract used in supplements, and no—it's different from the culinary basil you cook with. This product gives you holy basil in capsule form.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it in pregnancy because animal studies raised concerns and human safety isn't established. While breastfeeding, there isn't enough reliable safety information either. Talk with your doctor or pharmacist about what's right for your situation.
What side effects should I expect?
Most people tolerate it well. The most common side effects from capsules are loose stools and nausea, though only a small number of people in studies experienced these. It's generally well tolerated short-term, but long-term safety data in humans are limited.
Does holy basil actually work for anxiety or diabetes?
The evidence we hold is insufficient to say whether it works for anxiety, diabetes, asthma, headache, infections, or dental plaque. That doesn't mean it doesn't—just that the research available isn't solid enough to establish it.
Is there anything else in these capsules besides holy basil?
Each capsule contains holy basil extract plus pullulan, which is an inactive ingredient that helps form the capsule. No fillers or unnecessary extras beyond that.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Holy Basil is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holy Basil label
Go deeper

The Full Monographs Behind Holy Basil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Holy Basil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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