No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Hyaluronic Acid Ingredients & Drug Interactions

by Douglas Laboratories

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Hyaluronic Acid is a dietary supplement by Douglas Laboratories with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Hyaluronic Acid by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hyaluronic acid, a naturally occurring substance your body produces that helps retain moisture in skin and connective tissue. It's sold here as an oral supplement.

The tablet also includes inactive ingredients — sodium hyaluronate, cellulose, vegetable stearate, and silica — which serve as binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Hyaluronic Acid's overall clinical evidence instead.

Moderate

Some clinical evidence supports Hyaluronic Acid for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dry eye — rated "Possibly Effective" (Natural Medicines).
  • On file: Venous leg ulcers — rated "Possibly Effective" (Natural Medicines).

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing wounds on the legs). For aging skin, allergic rhinitis (hay fever), and sexual dysfunction, the evidence we hold is insufficient to rate whether it works.

If you're considering it for dry eye or leg ulcers, talk with your doctor about whether the evidence fits your situation.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally and topically, hyaluronic acid appears to be well tolerated in most adults. The safety notes on file advise caution because long-term safety of supplements isn't fully studied, and there isn't enough data to confirm oral supplements are safe — so your doctor should clear it before you start.

Eye drops containing hyaluronic acid have rarely caused ocular pain; topical application can occasionally trigger eczema, redness, itching, or wound infection, though these are not common.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for hyaluronic acid in our data. You're welcome to use the medication checker on this page to confirm your exact prescriptions, and speak with your pharmacist or doctor if anything comes up.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Hyaluronic acid may help with dry eye or venous leg ulcers if your doctor thinks it's right for you. It's generally well tolerated when taken by mouth, but long-term safety data is limited.

Talk it over with your doctor or pharmacist before starting, especially if you're pregnant, nursing, or have any skin or eye concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hyaluronic Acid, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539021248
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 56954
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hyaluronic Acid by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
60
UPC/BARCODE
310539021248
IngredientAmount% DV
Hyaluronic Acid30 mg--

Other ingredients: Sodium Hyaluronate, Cellulose, Vegetable Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This product contains NO yeast, wheat gluten, soy, milk/dairy, corn, sugar, starch, artificial preservatives or genetically modified oraganisms (GMOs).

Vegetarian Source

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1-2 tablets daily or as directed by your healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

General

Formula #99154

FDA Statement of Identity

A Dietary Supplement

See for yourself

Hyaluronic Acid by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hyaluronic Acid by Douglas Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Hyaluronic Acid

No known
interactions
30 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Other (inactive) ingredients: Sodium Hyaluronate, Cellulose, Vegetable Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hyaluronic Acid by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Hyaluronic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Hyaluronic Acid, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.800.245.440
Pharmacist Counseling Corner

Hyaluronic Acid by Douglas Laboratories: Common Questions

Does Hyaluronic Acid by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Hyaluronic Acid. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Hyaluronic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does hyaluronic acid really work for dry eyes?
It's rated possibly effective for dry eye, which means there's some evidence supporting it — but it's not a slam-dunk cure. Ask your eye doctor whether it's worth trying for your particular situation.
Is it safe to take this while pregnant or breastfeeding?
The product facts don't include safety data for pregnancy or lactation, so we can't say either way. You'll need to ask your doctor or pharmacist before taking it during pregnancy or while nursing — they can weigh what's known and what fits your needs.
What are the side effects?
Taken by mouth, hyaluronic acid is generally well tolerated and most people don't report problems. Topical (skin) forms can sometimes cause eczema, redness, itching, or rarely wound infection. Eye drops have very rarely caused eye pain.
Does it have fillers or just the active ingredient?
It has inactive ingredients: sodium hyaluronate, cellulose, vegetable stearate, and silica, which are binders and fillers that help make the tablet. If you need a truly minimal-ingredient option, you'll want to compare brands.
Will this help my wrinkles or aging skin?
The evidence for aging skin is insufficient — we don't have enough data to say whether it works for that. If you're interested in it for wrinkles, ask your dermatologist what the research supports.
Can I take this with my medications?
No interactions are documented for hyaluronic acid, so there's no known conflict from that angle. Still, run your exact medications through the checker on this page and confirm with your pharmacist just to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hyaluronic Acid is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hyaluronic Acid label
Go deeper

The Full Monographs Behind Hyaluronic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hyaluronic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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