No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Hyaluronic Acid Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Hyaluronic Acid is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Hyaluronic Acid by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: HyaMax, a form of hyaluronic acid. Hyaluronic acid is a naturally occurring compound that your body uses to keep tissues hydrated and maintain skin elasticity.

The capsule also contains plant fiber, cellulose, and water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Hyaluronic Acid's overall clinical evidence instead.

Moderate

Some clinical evidence supports Hyaluronic Acid for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dry eye — rated "Possibly Effective" (Natural Medicines).
  • On file: Venous leg ulcers — rated "Possibly Effective" (Natural Medicines).

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing wounds in the legs). For aging skin, allergic rhinitis (hay fever), and sexual dysfunction, the evidence available isn't strong enough to rate whether it works — we simply don't have enough reliable data.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth or applied to skin, hyaluronic acid appears to be well tolerated by most adults. Topically, it's occasionally been reported to cause eczema, redness, itching, wound bleeding, or wound infection.

Rarely, eye drops containing hyaluronic acid have caused eye pain. Long-term safety of oral hyaluronic acid supplements hasn't been fully studied.

The safety data for this ingredient is limited. Our facts don't include specific pregnancy or breastfeeding safety information — talk with your doctor or pharmacist about whether it's right for you if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your exact medications through the search tool on this page to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Pure Encapsulations' Hyaluronic Acid is generally well tolerated and has no documented medication interactions. It may help with dry eye or leg ulcers, though the evidence is modest.

Because long-term safety data is incomplete and the safety picture is limited, it's smart to check in with your doctor or pharmacist before you start — especially if you're pregnant, breastfeeding, or have any skin conditions you're treating.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hyaluronic Acid, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298006048
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 293973
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hyaluronic Acid by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
766298006048
IngredientAmount% DV
HyaMax70 mg--

Other ingredients: Plant Fiber, Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, with or between meals, or as directed by a health professional.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements.

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Formulation

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Supports skin hydration, joint, lubrication and comfort

Gluten-free, non-GMO & hypoallergenic

Gluten-free, non-GMO & hypoallergenic

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

HyaMax is a U.S.A registered trademark of Frenchem.

FDA Disclaimer Statement

This statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Hyaluronic Acid by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hyaluronic Acid by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

HyaMax

No known
interactions
70 mg per serving Form: Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

HyaMax monograph & interactions

Other (inactive) ingredients: Plant Fiber, Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hyaluronic Acid by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Hyaluronic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Hyaluronic Acid, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Hyaluronic Acid by Pure Encapsulations: Common Questions

Does Hyaluronic Acid by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Hyaluronic Acid. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Hyaluronic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is HyaMax, and why is it in this product?
HyaMax is a form of hyaluronic acid, a substance your body naturally produces to keep skin and tissues hydrated. In supplements, it's used for its role in maintaining moisture and skin health.
Does hyaluronic acid work for dry skin or wrinkles?
For dry eye, it's possibly effective. For wrinkles and aging skin in general, there isn't enough strong evidence to say whether it works — the research just isn't there yet.
Are there any side effects I should know about?
When taken by mouth or applied to skin, hyaluronic acid is generally well tolerated. Topically, it occasionally causes eczema, redness, itching, or wound irritation. Eye drops with it have rarely caused eye pain.
Is oral hyaluronic acid safe long-term?
It appears safe in the short term for most adults, but long-term safety hasn't been fully studied. Before taking it regularly, especially if you have any health concerns, check with your doctor or pharmacist.
Can I take this if I'm pregnant or breastfeeding?
Our data doesn't include specific safety information for pregnancy or breastfeeding. Talk with your doctor or pharmacist — they can give you personalized advice based on your situation.
Does this product have fillers?
Yes, it contains plant fiber and cellulose as inactive ingredients — these help hold the capsule together but aren't the active ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hyaluronic Acid is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hyaluronic Acid label
Go deeper

The Full Monographs Behind Hyaluronic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hyaluronic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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