Hyaluronic Acid Complex Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hyaluronic Acid Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hyaluronic Acid Complex is a dietary supplement by Nature's Truth with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Hyaluronic Acid Complex by Nature's Truth
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains three active ingredients. Hyaluronic acid is a natural compound found in the body that holds water and is involved in joint lubrication and skin hydration.
The product also includes methylsulfonylmethane (often called MSM) and hydrolyzed collagen (a broken-down form of the structural protein collagen). Together they're intended to support skin, joint, and connective tissue health.
The capsules also contain inactive ingredients — gelatin, magnesium stearate, silica, and rice powder — which help hold the formula together and make it easier to swallow.
Does it work?
Moderate evidence
Hyaluronic acid is possibly effective for dry eye and for venous leg ulcers (slow-healing wounds in the leg caused by circulation problems). For aging skin, hay fever, and sexual dysfunction, the evidence isn't established enough to rate it.
We have no effectiveness data on file for methylsulfonylmethane or hydrolyzed collagen in this product, so we can't tell you how well they work or what they're meant to do.
How safe is it?
Well-documented data
Hyaluronic acid (when taken by mouth or applied to skin) is generally well tolerated. However, long-term safety data for oral supplements isn't fully studied, so caution is warranted with long-term use.
The safety information available is limited, and your doctor should clear it before you start. The most common side effects reported with topical use (not oral) include eczema, redness, itching, wound bleeding, and wound infection.
Eye drops containing hyaluronic acid have rarely caused eye pain. The facts do not provide pregnancy or breastfeeding safety information for any of these ingredients, so talk with your doctor or pharmacist about whether this is right for you if you're pregnant or nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, we couldn't verify methylsulfonylmethane or hydrolyzed collagen.
Before you start, it's smart to review your exact medications with your pharmacist or check them through the search tool on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Hyaluronic Acid Complex might interest you if you're looking to support dry eyes or have a slow-healing leg wound, and you want a joint and skin supplement. Because long-term safety data is limited and we couldn't check all ingredients for drug interactions, talk with your doctor or pharmacist before you start — especially if you're pregnant, nursing, or take any medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hyaluronic Acid Complex, straight from the product label.
| Brand | Nature's Truth |
|---|---|
| Barcode (UPC) | 840093101198 |
| Net contents | 50 Quick Release Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 306726 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hyaluronic Acid Complex by Nature's Truth, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Methylsulfonylmethane | 400 mg | -- |
| Hyaluronic Acid | 100 mg | -- |
| Collagen, Hydrolyzed | 400 mg | -- |
Other ingredients: Gelatin, Magnesium Stearate, Silica, Rice, Powder
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
100% Quality Satisfaction guarantee Vitamins
Formula
Hyaluronic acid complex 900 mg per serving
Potent trio Hyaluronic acid, MSM, and collagen
Formulation
Gluten free Non GMO
No gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives. Non-GMO
Our Non-GMO Pledge Visit our website
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take three (3) quick release capsules daily, preferably with a meal.
Precautions
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.
Keep out of reach of children.
Storage
Store in a cool, dry place.
Brand IP Statement(s)
Copyright 2021 Nature's Truth LLC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hyaluronic Acid Complex by Nature's Truth label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hyaluronic Acid Complex by Nature's Truth
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Quick Release Capsule(s) Dosage formCapsule Servings per container16 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Methylsulfonylmethane
Hyaluronic Acid
No knowninteractions
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...
Hyaluronic Acid monograph & interactionsCollagen, Hydrolyzed
Other (inactive) ingredients: Gelatin, Magnesium Stearate, Silica, Rice, Powder. These complete the product’s ingredient list but are not active constituents.
Hyaluronic Acid Complex by Nature's Truth Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Hyaluronic Acid Complex. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Hyaluronic Acid Complex, from the product label.
Nature's Truth
See all Nature's Truth products- Name
- Nature's Truth LLC
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-844-544-1030
- Web Address
- naturestruth.com
Hyaluronic Acid Complex by Nature's Truth: Common Questions
Does Hyaluronic Acid Complex by Nature's Truth interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is hyaluronic acid, and what does it do in this supplement?
Is this safe to take long-term?
Can I take this if I'm pregnant or breastfeeding?
What are the inactive ingredients, and are there any fillers?
Does this interact with any medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hyaluronic Acid Complex is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hyaluronic Acid Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hyaluronic Acid Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC