Knotgrass Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Knotgrass against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Knotgrass is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for source of resveratrol, heart and circulation support, lyme disease support (traditional/herbalist use).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Knotgrass by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: certified organic Knotgrass (Polygonum aviculare) dried herb liquid extract. The other ingredient is Menstruum, which is used in the extraction process.
Does it work?
Couldn't assess
The evidence for Knotgrass in treating gingivitis is insufficient—there isn't enough reliable data to say whether it works for that purpose. We can't recommend it based on what's been studied so far.
How safe is it?
Some data gaps
Knotgrass is generally well tolerated for short-term use, but human safety data are limited. It can cause digestive side effects in some people.
The safety data advises against using it during pregnancy because some compounds in it may affect the uterus. There isn't enough safety information to use it while breastfeeding either.
If you're pregnant or nursing, talk with your doctor or pharmacist before considering this product.
Meds to double-check
No known interactions
No interactions are documented for the ingredient we checked, so there's no specific medication type you need to double-check before starting this product. That said, if you take any prescription medications, run them by your own doctor or pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
Knotgrass from Herbal Terra is a single-ingredient herbal liquid with no documented drug interactions, but the evidence for treating gingivitis just isn't there yet. It's generally tolerated short-term, though it can upset your digestion, and it's not advised in pregnancy or while breastfeeding.
Talk it over with your doctor or pharmacist to see if it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Knotgrass, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 0617503377166 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2020 |
| DSLD ID | 234030 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Knotgrass by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| certified organic Knotgrass (Polygonum aviculare) dried herb liquid extract | 970 mg | -- |
Other ingredients: Menstruum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.
FDA Disclaimer Statement
Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Manufactured in the USA in an FDA registered facility
Sugar free
Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract
Non GMO
No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free
Precautions
Caution May have contraindications.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing, or if you are on any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry, dark place.
Formula
Polygonum aviculare
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA Made in an FDA registered facility Natural Gluten Free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Knotgrass by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Knotgrass by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Certified organic Knotgrass (Polygonum aviculare) dried herb liquid extract
No knowninteractions
Japanese knotweed (Polygonum cuspidatum) is an herb best known as a natural source of resveratrol and emodin, and it is used in traditional Chinese me...
Certified organic Knotgrass (Polygonum aviculare) dried herb liquid extract monograph & interactionsOther (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.
Knotgrass by Herbal Terra Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Knotgrass. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Knotgrass, from the product label.
Knotgrass by Herbal Terra: Common Questions
Does Knotgrass by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Knotgrass while pregnant?
Can I use Knotgrass while breastfeeding?
Does Knotgrass actually work for gingivitis?
What side effects might I notice?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Knotgrass is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Knotgrass’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Knotgrass's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 1 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Knotweed 1 reference
- Gonzalez Begne M, Yslas N, Reyes E, et al. Clinical effect of a Mexican sanguinaria (Polygonum aviculare L.) on gingivitis. J Ethnopharmacol 2001;74:45-51..
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC