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Dietary supplement

L-Lysine Powder 960 mg Ingredients & Drug Interactions

by Carlson

Powder Category: Amino Acid/protein
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

L-Lysine Powder 960 mg is a dietary supplement by Carlson with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Lysine Powder 960 mg by Carlson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 1 active ingredient: L-Lysine, an amino acid your body uses for protein synthesis and immune function. L-Lysine is supplied as a powder at 960 mg per serving.

There are no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: immune and tissue health stress support.
  • We looked for evidence on: Herpes labialis (cold sores), Stress, Protein synthesis, Collagen formation, Wound healing.
  • The strongest evidence on file: Lysine is rated "Possibly Effective" for Herpes labialis (cold sores) (Natural Medicines).
  • Also on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Stress.

L-Lysine is possibly effective for herpes labialis (cold sores) — that's where the best evidence sits. For child growth, pressure ulcers, and diabetic foot ulcers, the evidence isn't established enough for us to rate it.

The evidence, ingredient by ingredient Lysine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Lysine is generally well tolerated at typical doses. High amounts may cause stomach upset, and long-term safety from supplements hasn't been well studied.

The most common side effects from oral lysine are abdominal pain, diarrhea, and indigestion. There is one case report of oral lysine linked to kidney inflammation progressing to chronic kidney failure, though this is rare.

For pregnancy, supplement safety hasn't been well studied — lysine from food is fine, but check with your doctor before taking a supplement. For breastfeeding, there isn't enough reliable information, so caution is advised.

Side effects, ingredient by ingredient Lysine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lysine.
  • The most serious interaction on file is rated Minor.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a 5-HT4 agonist medication, check with your pharmacist before starting this supplement — lysine may reduce its effectiveness (Minor severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

If you're dealing with cold sores, L-Lysine may help. But if you take a 5-HT4 agonist medication, check with us first.

High doses and long-term use haven't been fully studied, so stick to typical amounts. Talk to your pharmacist if you're pregnant, breastfeeding, or on any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Lysine Powder 960 mg, straight from the product label.

Brand Carlson
Barcode (UPC) 088395068850
Net contents 3.53 Ounce(s); 100 Gram(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 337537
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Lysine Powder 960 mg by Carlson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.2 Gram(s)
Maximum serving Sizes:
1.2 Gram(s)
Servings per container
83
UPC/BARCODE
088395068850
IngredientAmount% DV
L-Lysine960 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Carlson Providing the highest quality nutritional supplements since 1965

Formula

L-Lysine is an essential amino acid that promotes immune and tissue health, provides stress support, and is an important building block for protein.

Free-form amino acid

Precautions

Warning: Pregnant or lactating women or those with kidney problems should consult with their doctor before using this product.

Formulation

Potency & quality guaranteed An FDA regulated facility

This product may vary in appearance and consistency.

Immune function Stress support Tissue health

Gluten-free Milk/casein-free

Storage

This product is sold by weight not volume.

Keep bottle tightly closed. Store away from heat and moisture.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults: take 1/2 teaspoonful (one level scoopful) daily mixed into food or liquid.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

L-Lysine Powder 960 mg by Carlson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Lysine Powder 960 mg by Carlson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.2 Gram(s) Dosage formPowder Servings per container83 Amounts shown are per serving.

L-Lysine

Interacts with
1 drug
960 mg per serving Form: L-Lysine Hydrochloride

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine monograph & interactions
Interaction report

L-Lysine Powder 960 mg by Carlson Drug Interactions

Want to check YOUR meds against L-Lysine Powder 960 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Lysine Powder 960 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for L-Lysine Powder 960 mg, from the product label.

Carlson

See all Carlson products
Name
Carlson Division of J.R. Carlson Laboratories, Inc.
City
Lincolnshire
State
IL
ZipCode
60069
Phone Number
888-234-5656
Web Address
carlsonlabs.com
Pharmacist Counseling Corner

L-Lysine Powder 960 mg by Carlson: Common Questions

Does L-Lysine Powder 960 mg by Carlson interact with any medications?
Yes. Based on its ingredients, L-Lysine Powder 960 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Lysine Powder 960 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does L-Lysine help with cold sores?
Yes, L-Lysine is possibly effective for herpes labialis (cold sores). It's one of the uses with decent research backing. That said, results vary from person to person.
What are the side effects of L-Lysine?
Most people tolerate it well. At typical doses, the main side effects are stomach upset, diarrhea, abdominal pain, and indigestion — especially at higher amounts. Long-term safety hasn't been thoroughly studied.
Is L-Lysine safe during pregnancy?
Lysine from food is fine, but supplement safety in pregnancy hasn't been well studied. Talk with your doctor before taking a supplement to decide what's right for you.
Can I take L-Lysine while breastfeeding?
There isn't enough reliable information on supplement use while breastfeeding, so caution is advised. Talk with your pharmacist or doctor to weigh the pros and cons for your situation.
Is this just L-Lysine or does it have other ingredients?
This is pure L-Lysine — no inactive fillers or other ingredients are included. Each serving is 960 mg of L-Lysine as a powder.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Lysine Powder 960 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Lysine Powder 960 mg label
Go deeper

The Full Monographs Behind L-Lysine Powder 960 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Lysine Powder 960 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lysine 7 references
  1. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
  2. McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
  3. DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
  4. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  5. Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
  6. Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
  7. Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.

See these in context on the Lysine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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