No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Ornithine 500 mg Ingredients & Drug Interactions

by Bluebonnet

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Ornithine 500 mg is a dietary supplement by Bluebonnet with 1 active ingredient. Its ingredients are commonly taken for athletic performance and recovery, reducing fatigue, sleep and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Ornithine 500 mg by Bluebonnet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-Ornithine Hydrochloride, a form of the amino acid ornithine. Ornithine is a building block your body uses in various metabolic pathways, including some involved in immune function and wound healing.

The inactive ingredients are common capsule fillers and binders: cellulose, hypromellose, purified water, magnesium stearate, and silicon dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support nitric oxide synthesis and men's health.
  • We looked for evidence on: Athletic performance, Wound healing, Erectile dysfunction, Vascular function.
  • The strongest evidence on file: Ornithine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Ornithine is rated "Insufficient Reliable Evidence To Rate" for Wound healing.

L-Ornithine is possibly effective for athletic performance, based on the evidence we hold. For dry skin, insomnia, and periodontitis (gum inflammation), the evidence isn't established enough to rate it one way or the other — we don't have reliable data showing it works for those uses.

The evidence, ingredient by ingredient Ornithine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Ornithine is generally well tolerated in the short term, but long-term safety hasn't been well studied, so we don't know what happens if you take it for months or years. The safety data advises against use during pregnancy and while breastfeeding — there isn't enough data to know it's safe in those situations.

Side effects, ingredient by ingredient Ornithine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for this ingredient.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

This supplement may be worth considering if you're an athlete looking to support performance, since there's some evidence behind that use. If you're pregnant, nursing, or taking any regular medications, talk with your pharmacist first.

Also discuss with your doctor or pharmacist if you're thinking of taking this long-term, since long-term safety isn't well established.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Ornithine 500 mg, straight from the product label.

Brand Bluebonnet
Barcode (UPC) 743715000681
Net contents 50 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 314817
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Ornithine 500 mg by Bluebonnet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
50
UPC/BARCODE
743715000681
IngredientAmount% DV
L-Ornithine Hydrochloride500 mg--

Other ingredients: Cellulose, Hypromellose, Water, Purified, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Bluebonnet's L-Ornithine 500mg Vegetable Capsules are formulated with the free-form amino acid L-ornithine HCl to help support nitric oxide synthesis and men's health/performance.

Bluebonnet's KOF-K Certification #K-0000700

K Parve (Kosher)

Formulation

May support nitric oxide synthesis

Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans and sesame. Also free of corn, gluten, barley, rice, sodium and sugar.

Made with non GMO ingredients Gluten free

Nitric oxide synthesis

V Vegan

Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made with non GMO ingredients V Vegan K Parve (Kosher)

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily or as directed by a healthcare practitioner.

Storage

Store tightly closed in a cool, dry place.

See for yourself

L-Ornithine 500 mg by Bluebonnet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Ornithine 500 mg by Bluebonnet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

L-Ornithine Hydrochloride

No known
interactions
500 mg per serving

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement fo...

L-Ornithine Hydrochloride monograph & interactions

Other (inactive) ingredients: Cellulose, Hypromellose, Water, Purified, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Ornithine 500 mg by Bluebonnet Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Ornithine 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Ornithine 500 mg, from the product label.

Bluebonnet

Name
Bluebonnet Nutrition Corporation
Street Address
12915 Dairy Ashford
City
Sugar Land
State
TX
ZipCode
77478
Web Address
www.bluebonnetnutrition.com
Pharmacist Counseling Corner

L-Ornithine 500 mg by Bluebonnet: Common Questions

Does L-Ornithine 500 mg by Bluebonnet interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Ornithine 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Ornithine 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-Ornithine safe to take during pregnancy?
The safety data advises against it — there isn't enough information to know whether it's safe during pregnancy. Talk with your doctor or pharmacist for personalized advice.
Can I take this while breastfeeding?
The safety data advises against it — there isn't enough information about safety while nursing. Check with your doctor or pharmacist before using this supplement.
Does L-Ornithine actually work for athletic performance?
There's some evidence suggesting it may help with athletic performance — that's the one use where we have enough data to say it's possibly effective. For other claims like dry skin or sleep, the evidence isn't strong enough to rate.
What are the side effects?
No adverse effects are reported in the data we hold. That said, long-term safety hasn't been well studied, so if you're planning to take this regularly for months, discuss it with your pharmacist.
What does L-Ornithine do in my body?
It's an amino acid — a building block your body uses in several metabolic pathways, including processes tied to immune function and wound healing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Ornithine 500 mg label
Go deeper

The Full Monographs Behind L-Ornithine 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Ornithine 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ornithine 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the Ornithine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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