No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

L-Proline is a single amino acid — one of the building blocks your body uses to make and repair proteins. It's naturally present in foods like meat, dairy, and eggs.

This powder form delivers proline as a concentrated supplement without any added fillers.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proline product and its label doesn't state a use — see Proline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for L-Proline as a supplement is still developing. We hold insufficient reliable data to rate it for athletic performance, bone health (osteoporosis, fractures, or osteopenia), or wound healing.

That doesn't mean it doesn't work for these purposes — it means the trials we have aren't robust enough to say for sure one way or the other.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Proline from food is generally well tolerated, but how safe supplemental doses are hasn't been thoroughly studied. The facts advise caution with extra amounts unless your doctor recommends them.

There's also not enough data on safety while breastfeeding, so if you're nursing, talk with your doctor or pharmacist about whether this is right for you before starting.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-Proline.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

L-Proline is an amino acid with no documented medication interactions, so it won't interfere with your prescriptions. The evidence for what it does isn't solid yet, and long-term safety at supplement doses isn't well established.

If you're considering it for athletic performance, bone health, or wound healing, have that conversation with your doctor or pharmacist to see if it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000HUTHGR
Net contents 500 Gram(s); 17.6 Oz(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 254704
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2000 mg
Maximum serving Sizes:
2000 mg
Servings per container
250
UPC/BARCODE
X000HUTHGR
IngredientAmount% DV
L-Proline2000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

New - BulkSupplements L-Proline Powder (500 Grams)

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 2000 mg (about 3/4 tsp) once or twice daily, or as directed by a physician.

Storage

Store in a dry, cool place

See for yourself

L-Proline by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2000 mg Dosage formPowder Servings per container250 Amounts shown are per serving.

L-Proline

No known
interactions
2000 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Proline by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Proline by BulkSupplements.com: Common Questions

Does L-Proline by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-Proline safe to take while pregnant?
The safety data for supplemental L-Proline during pregnancy isn't on file in our records. Since the evidence isn't established either way, talk with your doctor or pharmacist for personalized advice before taking it.
Can I take this if I'm breastfeeding?
Safety while breastfeeding hasn't been established for supplemental doses. The caution here is real — there just isn't enough research. Check with your doctor or pharmacist before starting, especially since your nursing infant is involved.
Does L-Proline actually help with wound healing?
We hold insufficient reliable evidence to rate L-Proline for wound healing. The idea makes sense — proline is part of collagen, which is crucial for healing — but the trials we have aren't strong enough to confirm it works.
What's L-Proline actually for?
Proline is an amino acid your body uses to build collagen and other proteins. It's naturally in foods like meat and dairy. As a supplement, people take it hoping to support athletic performance, bone strength, and wound healing, though solid evidence for those uses is still lacking.
Are there any side effects?
No adverse effects are documented in our data. That said, safety at supplemental doses hasn't been thoroughly studied, so if you notice anything unusual after starting, let your doctor or pharmacist know.
Does this interact with my medications?
No interactions are documented between L-Proline and any medications in our data. You can search your specific drugs using the checker on this page to be sure, but based on what we hold, there's no known concern.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline label
Go deeper

The Full Monographs Behind L-Proline’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring