No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Serine 2,000 mg Ingredients & Drug Interactions

by Nutricost

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Serine 2,000 mg is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for memory and brain health, nervous system disorders (e.g., als research), mood and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Serine 2,000 mg by Nutricost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-serine, an amino acid at 2,000 mg per serving. L-serine is a compound your body can make on its own and also gets from food sources like eggs, dairy, and meat.

There are no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Serine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Serine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

L-serine is possibly effective for schizophrenia according to the research we have on file. For Alzheimer disease, ALS (Lou Gehrig's disease), back pain, PTSD, and cognitive function, the evidence isn't established — we don't have reliable data to say whether it works or doesn't.

If you're considering this for one of those other conditions, talk with your doctor about what the current science actually shows.

The evidence, ingredient by ingredient Serine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-serine is generally well tolerated, though supplement safety and long-term use haven't been thoroughly studied. The most common side effects are gastrointestinal — stomach pain, bloating, indigestion, loss of appetite, and nausea.

These are dose-dependent, meaning higher doses are more likely to cause them. At very high doses (above 25 grams daily), rare serious effects like reversible eye-movement problems (nystagmus) and seizures have been reported.

There isn't enough safety data on L-serine in pregnancy to know whether it's safe, so it's best avoided unless your doctor advises otherwise. Safety during breastfeeding hasn't been studied either — avoid supplements unless your doctor directs it.

Side effects, ingredient by ingredient Serine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-serine. That said, absence of documented interactions is not a guarantee none exist — run your specific medications through the checker on this page, and confirm with your doctor or pharmacist before you begin.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Nutricost L-Serine may be worth considering if you're exploring options for schizophrenia under your doctor's guidance. For other uses, the evidence isn't there yet.

Start with the full dose listed on the label only if your stomach tolerates it — smaller amounts first might help you avoid bloating or nausea. If you're pregnant, breastfeeding, or taking any medications, talk with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Serine 2,000 mg, straight from the product label.

Brand Nutricost
Barcode (UPC) 810014671383
Net contents 8 oz; 0.5 Pound(s); 227 Gram(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 270520
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Serine 2,000 mg by Nutricost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
113
UPC/BARCODE
810014671383
IngredientAmount% DV
L-Serine2000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, mix 1 scoop daily with 6-10 oz of water or as directed by your healthcare professional.

Precautions

Warning: For healthy individuals 18 years and older.

Consult a healthcare professional prior to use if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Notice: Store in a cool, dry place.

General Statements

Contents are sold by weight, not volume. Some settling may occur.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

2,000 mg per serving .5 lbs per container

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Quality Guaranteed Nutricost

Formulation

Vegetarian product

Non GMO Gluten Free Product

See for yourself

L-Serine 2,000 mg by Nutricost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Serine 2,000 mg by Nutricost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container113 Amounts shown are per serving.

L-Serine

No known
interactions
2000 mg per serving

Serine is an amino acid your body can make on its own and also gets from protein-rich foods, so most people do not need a supplement. L-serine has bee...

L-Serine monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Serine 2,000 mg by Nutricost Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Serine 2,000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Serine 2,000 mg, from the product label.

Nutricost

See all Nutricost products
Name
Nutricost
Street Address
351 E 1750 N
City
Vineyard
State
UT
ZipCode
84059
Phone Number
(866) 438-3694
Web Address
www.nutricost.com
Pharmacist Counseling Corner

L-Serine 2,000 mg by Nutricost: Common Questions

Does L-Serine 2,000 mg by Nutricost interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Serine 2,000 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Serine 2,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-serine and what does it do in the body?
L-serine is an amino acid — a building block your body uses to make proteins and other compounds. Your body produces it naturally and you also get it from foods like eggs and meat. In this supplement form, it's being studied for conditions like schizophrenia and Alzheimer disease, though the evidence for most uses isn't clear yet.
Will L-serine help with memory or thinking?
The evidence isn't established — we don't have reliable data showing whether L-serine improves cognitive function. If brain health is your goal, talk with your doctor about what's actually proven to help.
What side effects should I watch for?
The most common ones are stomach-related: bloating, stomach pain, indigestion, nausea, and loss of appetite. These tend to happen at higher doses. At very high doses (above 25 grams daily), rare serious effects like seizures have been reported. Start with a smaller amount if your stomach is sensitive.
Is this safe to take while pregnant?
There isn't enough safety data on L-serine supplements during pregnancy to know either way. It's best avoided unless your doctor advises it. Talk with your doctor or pharmacist about whether it's right for you.
Can I take this while breastfeeding?
Safety during breastfeeding hasn't been studied, so avoid supplements unless your doctor directs it. Ask your doctor or pharmacist whether this product is okay for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Serine 2,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Serine 2,000 mg label
Go deeper

The Full Monographs Behind L-Serine 2,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Serine 2,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serine 3 references
  1. Fridman V, Suriyanarayanan S, Novak P, et al. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019;92(4):e359-e370.
  2. Kantrowitz JT, Malhotra AK, Cornblatt B, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010 Aug;121(1-3):125-30. PubMed
  3. Levine TD, Miller RG, Bradley WG, et al. Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener. 2017;18(1-2):107-111. PubMed

See these in context on the Serine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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