No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Serine 500 mg Capsules Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Serine 500 mg Capsules is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for memory and brain health, nervous system disorders (e.g., als research), mood and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Serine 500 mg Capsules by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-serine, an amino acid at 500 mg per capsule. The capsule itself is made of gelatin, an inactive ingredient that holds the powder together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Serine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Memory and brain health support.
  • We looked for evidence on: Alzheimer disease, Cognitive function, Parkinson disease, Nervous system health, Age-related cognitive decline, Neurological support.
  • The closest evidence on file: Serine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Serine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Parkinson disease.

L-serine is rated possibly effective for schizophrenia based on the evidence we hold. For Alzheimer disease, ALS (Lou Gehrig's disease), back pain, PTSD, and cognitive function, the evidence isn't established — we don't have enough reliable data to say one way or the other.

The evidence, ingredient by ingredient Serine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-serine appears well tolerated in typical supplement doses, though side effects are dose-dependent. The most common ones are gastrointestinal: stomach pain, bloating, indigestion, loss of appetite, and nausea.

At very high doses — well above what's in this capsule — seizures have been reported rarely. Long-term safety of supplements isn't well established.

Don't use this product in pregnancy or while breastfeeding unless your doctor advises it. There isn't enough safety data in either situation to recommend it on your own.

Side effects, ingredient by ingredient Serine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for L-serine in our data. That doesn't guarantee none exist, so mention this supplement to your pharmacist if you're on any medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

L-serine might be worth considering if you're looking into it for schizophrenia, though talk with your doctor about whether it fits your situation. If you're pregnant, nursing, or have a history of seizures, check with your pharmacist or doctor first.

At the dose in this product, side effects are unlikely, but stomach upset is possible if you're sensitive.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Serine 500 mg Capsules, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003CQYZOR
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 312924
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Serine 500 mg Capsules by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
X003CQYZOR
IngredientAmount% DV
L-Serine500 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

L-Serine Capsules 500 mg per serving

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule once daily or as directed by a physician.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Always consult a physician before taking any dietary supplement.

Free of: Added sugar, soy, dairy, yeast, gluten, additives.

Precautions

Keep out of reach of children.

Storage

Store in a dry, cool place

General Statements

New Scan me

See for yourself

L-Serine 500 mg Capsules by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Serine 500 mg Capsules by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

L-Serine

No known
interactions
500 mg per serving

Serine is an amino acid your body can make on its own and also gets from protein-rich foods, so most people do not need a supplement. L-serine has bee...

L-Serine monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Serine 500 mg Capsules by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Serine 500 mg Capsules. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Serine 500 mg Capsules, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Serine 500 mg Capsules by BulkSupplements.com: Common Questions

Does L-Serine 500 mg Capsules by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Serine 500 mg Capsules. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Serine 500 mg Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-serine and what does it do in the body?
L-serine is an amino acid — a building block your body uses to make proteins and other compounds. It's found naturally in foods, and supplements add more to your diet. The evidence shows it may help with schizophrenia, but for most other uses we hold, the evidence isn't strong enough to say.
Will this give me stomach problems?
Most people tolerate L-serine well at supplement doses. But some experience gastrointestinal distress — bloating, indigestion, nausea, or stomach pain. It depends on the dose and how your stomach handles it. Start with a dose your pharmacist suggests and adjust if needed.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data to recommend L-serine supplements in pregnancy or while breastfeeding. It's best to avoid it unless your doctor specifically advises you to take it. Talk with your doctor or pharmacist before starting.
Does this product have fillers or other stuff in it?
The capsule is made of gelatin, which is an inactive ingredient that holds the powder. That's the only ingredient besides the L-serine itself.
Is L-serine safe to take long-term?
L-serine appears well tolerated at typical doses, but long-term safety of supplements hasn't been well established. If you're thinking about taking it regularly, ask your pharmacist or doctor to keep an eye on how you're doing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Serine 500 mg Capsules is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Serine 500 mg Capsules label
Go deeper

The Full Monographs Behind L-Serine 500 mg Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Serine 500 mg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serine 3 references
  1. Fridman V, Suriyanarayanan S, Novak P, et al. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019;92(4):e359-e370.
  2. Kantrowitz JT, Malhotra AK, Cornblatt B, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010 Aug;121(1-3):125-30. PubMed
  3. Levine TD, Miller RG, Bradley WG, et al. Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener. 2017;18(1-2):107-111. PubMed

See these in context on the Serine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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