No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Serine 550 mg Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Serine 550 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for memory and brain health, nervous system disorders (e.g., als research), mood and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Serine 550 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-serine, an amino acid your body uses to build proteins and support nerve and brain function. Each capsule provides 550 mg.

There are no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Serine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Serine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

The evidence for L-serine is mixed. It's rated possibly effective for schizophrenia based on available data.

For Alzheimer's disease, amyotrophic lateral sclerosis (ALS), back pain, post-traumatic stress disorder (PTSD), and cognitive function, there isn't enough reliable evidence yet to say whether it works.

The evidence, ingredient by ingredient Serine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-serine is generally well tolerated in the doses used medicinally, but long-term safety in supplements hasn't been fully established. The most common side effects are gastrointestinal—stomach pain, bloating, indigestion, loss of appetite, and nausea.

These are dose-dependent, meaning higher doses are more likely to cause them. At very high doses (above about 25 grams daily), rare serious effects like seizures have been reported.

There isn't enough safety data to recommend L-serine supplements during pregnancy, so it's best avoided unless your doctor advises it. Safety during breastfeeding hasn't been studied, so avoid supplements unless your doctor directs you to take it.

Side effects, ingredient by ingredient Serine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for L-serine in our data. Even so, it's always smart to mention any supplement you're taking to your doctor or pharmacist, especially if you're on multiple medications.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

L-serine may be worth considering if you're interested in schizophrenia support, though evidence is still evolving. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting—the safety data just isn't there yet.

For any other condition on the label, the evidence is too thin right now to say it'll help. Keep doses reasonable to avoid digestive upset.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Serine 550 mg, straight from the product label.

Brand BulkSupplements.com
Net contents 300 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 254761
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Serine 550 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
75
IngredientAmount% DV
L-Serine1650 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children!

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Free of: Sugar, soy, dairy, yeast, gluten or additives

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 3-4 capsules daily or as directed by a physician.

Storage

Storage: Keep dry, cool & dark

See for yourself

L-Serine 550 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Serine 550 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container75 Amounts shown are per serving.

L-Serine

No known
interactions
1650 mg per serving

Serine is an amino acid your body can make on its own and also gets from protein-rich foods, so most people do not need a supplement. L-serine has bee...

L-Serine monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Serine 550 mg by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Serine 550 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Serine 550 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Road
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Serine 550 mg by BulkSupplements.com: Common Questions

Does L-Serine 550 mg by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Serine 550 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Serine 550 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-serine, and what does it do in my body?
L-serine is an amino acid—a building block for proteins—that your body uses to build and support nerve and brain tissue. It's found naturally in foods, but this supplement provides a concentrated dose in capsule form.
Does this actually work for memory or brain fog?
The evidence for cognitive function (including memory) is insufficient right now—we just don't have enough reliable studies. L-serine is possibly effective for schizophrenia, but for other brain and nerve conditions on the label, the data is too limited to say it helps.
What side effects should I watch for?
Most people tolerate L-serine well, but it can cause stomach upset—abdominal pain, bloating, indigestion, nausea, or loss of appetite—especially at higher doses. If you stick to the label dose (550 mg per capsule), these are unlikely but possible. Very high doses (over 25 grams daily) are rare but can trigger seizures.
Can I take this while pregnant or breastfeeding?
No—there isn't enough safety data on L-serine supplements during pregnancy, so it's best to avoid it unless your doctor tells you otherwise. Safety during breastfeeding hasn't been studied either, so talk with your doctor or pharmacist first.
Are there any fillers or added ingredients?
No—this product lists no inactive ingredients, so you're getting just L-serine in the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Serine 550 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Serine 550 mg label
Go deeper

The Full Monographs Behind L-Serine 550 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Serine 550 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serine 3 references
  1. Fridman V, Suriyanarayanan S, Novak P, et al. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019;92(4):e359-e370.
  2. Kantrowitz JT, Malhotra AK, Cornblatt B, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010 Aug;121(1-3):125-30. PubMed
  3. Levine TD, Miller RG, Bradley WG, et al. Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener. 2017;18(1-2):107-111. PubMed

See these in context on the Serine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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