No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lactase Enzyme 250 mg Ingredients & Drug Interactions

by KAL

Softgel Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lactase Enzyme 250 mg is a dietary supplement by KAL with 1 active ingredient. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lactase Enzyme 250 mg by KAL

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

KAL Lactase Enzyme 250 mg is a single-ingredient supplement containing lactase, the enzyme that breaks down milk sugar (lactose). The rest of the capsule is made up of inactive ingredients: gelatin, sunflower seed oil, glycerin, lecithin, titanium dioxide, and sorbitol — common fillers and capsule materials.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Lactase's overall clinical evidence instead.

Strong

Strong clinical evidence supports Lactase for:

Why this rating?
  • The label markets general wellness (“digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Natural Medicines).

Lactase is effective for lactose intolerance — it helps your body digest dairy when your own lactase production is low or absent. For other uses like prematurity or colic in infants, the evidence isn't established enough in our data to rate it one way or the other.

The evidence, ingredient by ingredient Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when you use it as directed. A rare case of allergic contact dermatitis and nasal allergies has been reported in someone exposed to powdered lactase at work, so if you know you're allergic to lactase itself, this product isn't for you.

In pregnancy and breastfeeding, the safety data suggests it's likely safe, though the research is limited — because it works only in your gut and doesn't enter your bloodstream in significant amounts, talk with your doctor or pharmacist first if you want to use it regularly while pregnant or nursing.

Side effects, ingredient by ingredient Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we could check.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward choice for anyone whose body doesn't break down lactose well — it's an enzyme that does the work your digestive system can't. Because lactase stays in your gut and doesn't interact with medications in our data, it's generally a low-risk option.

If you're pregnant, nursing, or have any concerns about allergies, a quick word with your pharmacist or doctor is worth it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactase Enzyme 250 mg, straight from the product label.

Brand KAL
Barcode (UPC) 021245802068
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 322917
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactase Enzyme 250 mg by KAL, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
021245802068
IngredientAmount% DV
Lactase250 mg--

Other ingredients: Gelatin, Sunflower Seed Oil, Glycerin, Lecithin, Titanium Dioxide, Sorbitol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

2 Daily

Directions: Take 2 softgels daily with a meal or glass of water. Use only as directed.

Brand IP Statement(s)

KAL Trust Quality Since 1932

Formulation

Digestive Support ActivGels Liquid-fill softgels Softgel image for illustration only

Made without soy

General Statements

PCR Bottle

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Formula

Discussion: KAL Lactose enzyme is intended for people with a lactose intolerance and is intended to provide nutritive support for the healthy digestion of milk sugar. FCC Units (Food Chemical Codex Units) provide standards to define the quality of food-grade substances in terms of identity, strength and purity.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Lactase Enzyme 250 mg by KAL label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lactase Enzyme 250 mg by KAL

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Lactase

No known
interactions
250 mg per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Other (inactive) ingredients: Gelatin, Sunflower Seed Oil, Glycerin, Lecithin, Titanium Dioxide, Sorbitol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactase Enzyme 250 mg by KAL Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lactase Enzyme 250 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lactase Enzyme 250 mg, from the product label.

KAL

See all KAL products
Name
Nutraceutical Corp.
Web Address
www.nutraceutical.com
Pharmacist Counseling Corner

Lactase Enzyme 250 mg by KAL: Common Questions

Does Lactase Enzyme 250 mg by KAL interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lactase Enzyme 250 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lactase Enzyme 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does lactase do?
Lactase is an enzyme that breaks down lactose, the natural sugar in milk and dairy. If your body doesn't make enough of its own lactase, taking this supplement helps you digest dairy without stomach upset.
Is lactase safe for babies with colic?
The evidence for colic isn't established well enough in our data to say whether it works or doesn't. Talk with your pediatrician before giving this to an infant — they can help you figure out if it's right for your baby.
Can I take this if I'm pregnant or breastfeeding?
The safety data says it's likely safe in pregnancy and breastfeeding because it works only in your gut. But the research is limited, so check with your doctor or pharmacist first if you plan to use it regularly.
What if I'm allergic to lactase?
A rare case of allergic reaction to lactase has been reported in someone exposed to powdered lactase at work. If you know you're allergic to lactase itself, this product isn't for you.
Will this interact with my medications?
No interactions are documented in our data. Because lactase works only in your digestive tract and doesn't enter your bloodstream, the risk is low — but if you want to be certain about a specific medication, use the checker on this page or ask your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactase Enzyme 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactase Enzyme 250 mg label
Go deeper

The Full Monographs Behind Lactase Enzyme 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lactase Enzyme 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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