No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 9 ingredients. Check your meds →
Dietary supplement

Lacto Ingredients & Drug Interactions

by Enzymedica

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lacto is a dietary supplement by Enzymedica with 9 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lacto by Enzymedica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.

Lacto contains 9 active digestive enzymes. Lactase breaks down milk sugar (lactose); lipase handles fats; protease works on proteins; and the other five — amylase, cellulase, invertase, glucoamylase, alpha-galactosidase, and maltase — help break down different carbohydrates and fibers.

The capsule itself contains cellulose and water as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: dairy digestion and lactose intolerance discomfort.
  • We looked for evidence on: Lactose intolerance, gas and bloating, casein intolerance, dairy discomfort.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase in this product is effective for lactose intolerance. The evidence for the other enzymes — protease, lipase, and the carbohydrate-digesting ones — isn't established in our data.

Lipase and lactase have been studied for inflammatory bowel disease, dyspepsia, and prematurity, but the evidence was too limited to rate them one way or the other.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease, lipase, and lactase are generally well tolerated in most adults, though digestive upset is possible and rare allergic reactions have been reported (especially in workers exposed to powdered enzyme dust). During pregnancy, the safety data is thin — protease should be avoided unless prescribed, while lipase and lactase carry caution because there isn't enough data to be sure.

Breastfeeding hasn't been well studied for lipase or protease, so check with your doctor; lactase is likely safe but ask first. This product is not for premature infants.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That's not a guarantee none exist — always verify your exact medications using the tool on this page, or ask your pharmacist to double-check.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have lactose intolerance, lactase in this product works. If you're taking any prescriptions, verify them against the checker on this page.

Pregnant or breastfeeding? Talk to your doctor or pharmacist — there isn't much safety data for most of these enzymes in those situations.

Otherwise, digestive enzymes are generally well tolerated.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lacto, straight from the product label.

Brand Enzymedica
Barcode (UPC) 670480241219
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 328888
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lacto by Enzymedica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
670480241219
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Maltase0 NP--

Other ingredients: Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Many people have difficulty digesting meals containing dairy, resulting in discomforts like occasional gas and bloating. This may occur due to the body's deficiency of enzymes that break down dairy.

Most Advanced #1 selling enzyme brand

Toll-free: 1-888-918-1118 | enzymedica.com

Formula

Lacto contains lactase and eight other enzymes that work synergistically to digest dairy sugars, proteins and fats. Thera-blend enzymes are comprised of multiple variants which are blended to work synergistically throughout the broad pH range of the human body.

Vegan & Kosher KOF-K (Kosher) Parve #K1840

Formulation

Complete dairy digestion may naturally reduce discomforts which are common to lactose and casein intolerance.

No fillers added

Made in USA with global ingredients

Non GMO

Digestive Most advanced dairy digestion formula Optimized support for lactose and casein intolerance Breaks down entire meal

Vegan & Kosher

Contains no: gluten, milk, casein, soy, egg, artificial colors or flavors

Suggested/Recommended/Usage/Directions

Recommended use: 1 capsule with each meal containing dairy. More may be taken as needed.

Brand IP Statement(s)

Enzymedica The enzyme experts

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

KOF-K (Kosher) Parve #K1840

Precautions

Do not use if safety seal is broken or missing.

Please keep out of reach of children

Storage

Keep closed in dry place; avoid excessive heat.

See for yourself

Lacto by Enzymedica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lacto by Enzymedica

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

0 NP per serving

Protease

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Lipase

No known
interactions
0 NP per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Lactase

No known
interactions
0 NP per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Cellulase

0 NP per serving

Invertase

0 NP per serving

Glucoamylase

0 NP per serving

Alpha-Galactosidase

0 NP per serving

Maltase

0 NP per serving

Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lacto by Enzymedica Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lacto. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lacto, from the product label.

Enzymedica

See all Enzymedica products
Name
Enzymedica, Inc.
Street Address
771 Commerce Drive
City
Venice
State
FL
ZipCode
34292
Phone Number
1-888-918-1118
Web Address
enzymedica.com
Pharmacist Counseling Corner

Lacto by Enzymedica: Common Questions

Does Lacto by Enzymedica interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lacto. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lacto contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Lacto really work for lactose intolerance?
Lactase, the main enzyme for milk sugar, is effective for lactose intolerance. The other enzymes in the formula haven't been proven to work for specific conditions in our data.
Can I take Lacto while pregnant?
The safety data is sparse. Lactase is likely safe, but protease should be avoided unless your doctor prescribes it, and lipase hasn't been studied enough. Talk to your doctor or pharmacist before starting, especially if you're taking it regularly.
Is it safe to breastfeed while using Lacto?
Limited data exists for protease and lipase during breastfeeding — check with your healthcare provider first. Lactase should be okay, but ask your doctor or pharmacist to confirm it's right for you.
What are the side effects?
Most people tolerate it well. Digestive upset is possible, and rare allergic reactions have been reported — especially in people exposed to powdered enzyme dust. If you develop rash, breathing trouble, or severe stomach pain, stop and call your doctor.
Can I give this to my premature baby?
No. The safety data shows serious digestive problems, including intestinal inflammation, when enzymes like lipase are given to premature infants. Use only under a doctor's supervision.
What do all these enzymes do?
Lactase breaks down milk sugar; lipase handles fats; protease breaks down proteins; and the others (amylase, cellulase, invertase, glucoamylase, alpha-galactosidase, maltase) help digest different carbohydrates and fiber. Together, they're meant to help your digestive system process food.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lacto is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lacto label
Sources

Sources & How We Checked

Lacto's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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