Liver SAP By NFH Overview & Drug Interactions

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Milk thistle (Silybum marianum) is a plant belonging to the aster family (Asteraceae). It is native to the Mediterranean region and is widely cultivated in many parts of the world. The plant is known for its milk-white veins on the leaves, which gives it its name. Milk thistle has a long history of use in traditional medicine, and is extremely popular as a dietary supplement, making it one of the most well-known plants in the world. It is purported to have liver-protectant effects and has been used to treat liver disorders such as hepatitis and cirrhosis. It has also been used to treat gallbladder problems and high cholesterol. While there are a number of compounds in milk thistle, one of the active constituents, silymarin, is thought to be responsible for many of its effects, and dietary supplements often report using a standardized amount (generally 70% to 80% silymarin in extracts).

Alpha-lipoic acid (ALA) is a naturally occurring compound that is made by the body and is also found in some foods, such as spinach, broccoli, and potatoes. It plays a role in energy production in the body and acts as an antioxidant, helping to protect cells from damage caused by free radicals. ALA has been studied for its potential health benefits, including the treatment of certain types of nerve damage, diabetes, and liver disease.

Schisandra is a plant that is native to parts of Asia, and is known for its small, red berries. These berries are often dried and sold as a dietary supplement to be used as a natural remedy for a wide range of health conditions, including fatigue, anxiety, and respiratory problems. Some people also use schisandra to improve sleep quality and reduce the symptoms of menopause. It is considered an 'adaptogen', which is believed to help the body adapt to stress.

Artichoke (Cynara scolymus) is a perennial plant native to the Mediterranean region that is known for its edible flower buds. Artichokes are a good source of fiber, vitamin C, and other nutrients. Artichoke has a history of use in traditional medicine, and studies show it may have a mild cholesterol-lowering effect and has also been used for gastrointestinal problems, such as heartburn and constipation. Although several parts of the artichoke have been used medicinally, for its use in dietary supplements, a standardized leaf extract is often used.

Dandelion is a plant that belongs to the family Asteraceae. It is native to Europe, Asia, and the Americas, and is known for its distinctive, bright yellow flowers and puffy, white seed heads. Although considered a weed by many, it is considered valuable for a number of reasons as it can be used as food, in medicine, and to attract pollinators. Dandelion has a long history of use as a medicinal plant. It has been used to treat a variety of conditions, including liver and gallbladder problems, kidney disorders, skin conditions, and digestive issues. It is also purported to have a diuretic effect and dietary supplements containing dandelion often market it for being able to help reduce water retention.

Methionine is an essential amino acid, meaning it must be obtained through the diet since the body cannot produce it on its own. It plays a crucial role in protein synthesis and various metabolic processes. Methionine is commonly found in protein-rich foods like meat, fish, dairy products, and certain plant-based sources, making it an important component of a balanced diet to support overall health and proper bodily functions.

N-acetyl cysteine (NAC) is derived from the amino acid cysteine. It is used as a prescription medication to treat acetaminophen overdose and to help thin mucus in people with certain respiratory conditions. It is also used as a dietary supplement. NAC has a number of potential health benefits. It is a source of the antioxidant enzyme glutathione, which is important for protecting cells from oxidative stress and supporting immune function. It also may have anti-inflammatory effects and studies show it may support healthy brain function. It is generally considered safe to take NAC supplements in recommended doses.