No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Lumbrokinase Enzymes Delayed Release Ingredients & Drug Interactions

by Dr. Mercola

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lumbrokinase Enzymes Delayed Release is a dietary supplement by Dr. Mercola with 2 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lumbrokinase Enzymes Delayed Release by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Dr. Mercola's Fibrinolytic Enzyme Blend” is a proprietary blend — the label gives one combined amount (11 mg) without saying how much of each component you get.

This product has two active ingredients: protease and lumbrokinase, both enzymes meant to support fibrin breakdown and circulation. Protease is a digestive enzyme that breaks down proteins.

The product also contains several inactive ingredients — microcrystalline cellulose, hydroxypropyl methylcellulose, gellan gum, rice, and ascorbyl palmitate — which are fillers and capsule materials.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proteolytic Enzymes (proteases) product and its label doesn't state a use — see Proteolytic Enzymes (proteases)'s own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness ratings on file for protease or lumbrokinase in this product. The evidence backing their use isn't established in the data we hold.

If you're curious about what research exists on these enzymes, your pharmacist or doctor can point you toward the latest clinical literature.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease is generally well tolerated for most adults, though some people experience digestive upset or allergic reactions. In rare cases, occupational or environmental exposure to proteolytic enzymes has triggered allergic rhinitis or asthma — something to keep in mind if you have sensitive airways.

Safety data during pregnancy is limited; the available evidence advises against use during pregnancy unless your doctor prescribes it. There's also little safety data during breastfeeding, so medical advice is recommended before using it while nursing.

We don't have safety information on file for lumbrokinase during pregnancy or breastfeeding.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, ask your pharmacist to verify this product against your specific medications using their full resources — we couldn't verify one of the main ingredients.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This delayed-release enzyme blend is generally well tolerated in adults with no documented medication interactions. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist first.

Run your medications through the checker on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lumbrokinase Enzymes Delayed Release, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 810487031998
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 308764
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lumbrokinase Enzymes Delayed Release by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
810487031998
IngredientAmount% DV
Protease0 NP--
Lumbrokinase0 NP--
Dr. Mercola's Fibrinolytic Enzyme Blend11 mg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Gellan Gum, Rice, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults, as a dietary supplement, take one (1) capsule daily on an empty stomach.

Precautions

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, have a blood coagulation or other medical condition, or are taking medication such as anticoagulants, consult your physician before taking this product.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Dr. Mercola Providing quality products since 2001.

See for yourself

Lumbrokinase Enzymes Delayed Release by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lumbrokinase Enzymes Delayed Release by Dr. Mercola

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dr. Mercola's Fibrinolytic Enzyme Blend

11 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Gellan Gum, Rice, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lumbrokinase Enzymes Delayed Release by Dr. Mercola Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lumbrokinase Enzymes Delayed Release. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lumbrokinase Enzymes Delayed Release, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Lumbrokinase Enzymes Delayed Release by Dr. Mercola: Common Questions

Does Lumbrokinase Enzymes Delayed Release by Dr. Mercola interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lumbrokinase Enzymes Delayed Release. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lumbrokinase Enzymes Delayed Release contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Safety data during pregnancy advises against it unless your doctor prescribes it. During breastfeeding, there's too little data to know either way — talk with your doctor or pharmacist for personalized advice. We don't have safety information on file for lumbrokinase in either situation.
What's protease and what does it do in this product?
Protease is a digestive enzyme that breaks down proteins. In this product, it's part of an enzyme blend meant to support fibrin breakdown and circulation.
Does this product cause side effects?
It's generally well tolerated, but some people experience digestive upset or allergic reactions. In rare cases, exposure to this type of enzyme has triggered allergic reactions affecting the nose, eyes, or airways — especially with occupational or airborne exposure.
What inactive ingredients are in this?
The capsule and filler materials include microcrystalline cellulose, hydroxypropyl methylcellulose, gellan gum, rice, and ascorbyl palmitate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lumbrokinase Enzymes Delayed Release is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lumbrokinase Enzymes Delayed Release label
Go deeper

The Full Monographs Behind Lumbrokinase Enzymes Delayed Release’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lumbrokinase Enzymes Delayed Release's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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