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Dietary supplement

Lyophilized Liver Extract Ingredients & Drug Interactions

by Ecological Formulas

Lyophilized Liver Extract label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lyophilized Liver Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Lyophilized Liver Extract is a dietary supplement by Ecological Formulas with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Liver Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lyophilized Liver Extract by Ecological Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Lyophilized Liver Extract by Ecological Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lyophilized Liver Extract by Ecological Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: liver extract, which is freeze-dried (lyophilized) organ tissue. It's packaged in gelatin capsules with silica and purified water as inactive ingredients.

Liver extract is a whole-food concentrate meant to deliver the nutritional compounds found in beef liver, including heme iron, B vitamins, and vitamin K.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for liver extract is sparse. For chronic fatigue syndrome, the data suggests it's possibly ineffective — meaning studies haven't shown meaningful benefit.

For hepatitis C, we don't have enough reliable evidence to rate whether it works. If you're considering this product for a specific health concern, talk it over with your doctor or pharmacist about what the evidence actually shows and whether other options might be better studied.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported in the data we hold, but a complete safety review hasn't been done. The bigger concerns are source and content.

Liver extract can deliver very high levels of vitamin A and iron, which can be problematic in large amounts or over time. Because it's made from raw animal liver from slaughterhouses — which may come from sick or diseased animals — there's a theoretical risk of contamination.

There's also concern about bovine spongiform encephalopathy (BSE, also called mad cow disease) in liver extracts from countries where the disease has been reported, though no cases of BSE transmission to humans from liver extract products have been documented. If you're pregnant, liver extract's high vitamin A content may harm your developing baby — the safety data advises against it unless your doctor tells you otherwise.

For breastfeeding, the safety data isn't on file, so talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take warfarin (Coumadin) — a blood thinner — or any iron supplements or iron-containing medications. Both interactions are Minor, but they're worth confirming with your own healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Liver extract is a whole-food supplement with minimal documented side effects in healthy adults, but it's not well studied and carries real concerns about vitamin A and iron content and potential source contamination. If you take warfarin or iron supplements, check with your doctor or pharmacist before starting.

If you're pregnant, avoid it unless advised otherwise by your healthcare provider. It's best to discuss this product with your doctor or pharmacist to decide if it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lyophilized Liver Extract, straight from the product label.

Brand Ecological Formulas
Barcode (UPC) 696859131875
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 304404
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lyophilized Liver Extract by Ecological Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
90
UPC/BARCODE
696859131875
IngredientAmount% DV
Liver Extract550 mg--

Other ingredients: Silica, Gelatin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Dietary Supplement

Formula

Lyophilized Liver Extract is a specially prepared nutritional supplement derived from organically grazed cattle and contains absolutely no trace of pesticides or synthetic hormones. Prior to extraction, the liver is lyophilized (freeze-dried) to protect the delicate nucleoproteins and polypeptides from denaturation. Then it is subject to hydrolysis to extract a high concentration of super oxide dismutase and catalase. These nutrients are potent antioxidants and serve as a support to liver function.

Formulation

Lyophilized Liver Extract is a specially prepared nutritional supplement derived from organically grazed cattle and contains absolutely no trace of pesticides or synthetic hormones.

The nutrient contained within these capsules are the purest and highest quality obtainable and contains no fillers, binders, excipients, flow agents or preservatives to ensure maximal tolerance and absorption.

Gluten free, casein free

Suggested/Recommended/Usage/Directions

Directions Take three capsules daily, or as directed by a physician.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lyophilized Liver Extract by Ecological Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lyophilized Liver Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lyophilized Liver Extract by Ecological Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Liver Extract

Interacts with
3 drugs
550 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Liver Extract monograph & interactions

Other (inactive) ingredients: Silica, Gelatin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lyophilized Liver Extract by Ecological Formulas Drug Interactions

Want to check YOUR meds against Lyophilized Liver Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Liver Extract 3

Individual Drug Interactions

The ingredients in Lyophilized Liver Extract interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lyophilized Liver Extract interact with drugs. Each result below shows which ingredient is responsible. Liver Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Lyophilized Liver Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Liver Extract2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
Liver Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lyophilized Liver Extract, from the product label.

Ecological Formulas

See all Ecological Formulas products
Name
Cardiovascular Research, LTD.
Street Address
1061-B Shary Circle
City
Concord
State
CA
ZipCode
94518
Pharmacist Counseling Corner

Lyophilized Liver Extract by Ecological Formulas: Common Questions

Does Lyophilized Liver Extract by Ecological Formulas interact with any medications?
Yes. Based on its ingredients, Lyophilized Liver Extract has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lyophilized Liver Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is liver extract safe for pregnant people?
No — liver extract can deliver very high vitamin A, which may harm a developing baby. The safety data advises against it unless your doctor tells you it's necessary and the benefits outweigh the risks. Talk with your doctor before considering it during pregnancy.
Can I take this if I'm breastfeeding?
The safety data for breastfeeding isn't on file. Talk with your doctor or pharmacist before using it while breastfeeding to weigh the pros and cons for your situation.
What is liver extract supposed to do?
It's a freeze-dried concentrate of beef liver meant to deliver nutrients found in whole liver, including heme iron, B vitamins, and vitamin K. However, evidence for most health claims is sparse or lacking.
Does this actually help with chronic fatigue?
The available evidence suggests it's possibly ineffective for chronic fatigue syndrome. If you're dealing with fatigue, talk with your doctor about approaches with stronger evidence behind them.
Where does the liver come from, and is it safe?
Liver extract is made from raw animal liver sourced from slaughterhouses, which may come from sick or diseased animals. There's also a theoretical risk of BSE (mad cow disease) contamination in products from certain countries, though no human cases have been reported. If you're concerned about the source, ask the maker which countries their liver comes from.
Could this cause an iron overload?
Liver extract contains heme iron. If you're already taking iron supplements or have a condition like hemochromatosis, combining them could increase your iron intake and raise the risk of problems. Check with your doctor or pharmacist if you're on iron therapy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lyophilized Liver Extract label
Go deeper

The Full Monographs Behind Lyophilized Liver Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Liver Extract

Interacts with 3 drugs

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before pu...

Read the full Liver Extract monograph →
Sources

Sources & How We Checked

Lyophilized Liver Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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