M-S-M Sulfur 1,000 mg Ingredients & Drug Interactions
by Carlson
What is this page for?
First and foremost: checking M-S-M Sulfur 1,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
M-S-M Sulfur 1,000 mg is a dietary supplement by Carlson with 1 active ingredient. Its ingredients are commonly taken for acne and oily skin, rosacea, seborrheic dermatitis and dandruff.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of M-S-M Sulfur 1,000 mg by Carlson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: sulfur at 1,000 mg per capsule. The capsule itself is made from hypromellose, an inert shell that holds the powder.
Does it work?
Couldn't assess
Sulfur is possibly effective for scabies and dandruff based on the evidence we have. For acne, hay fever, COPD, and the common cold, the evidence isn't strong enough yet to say whether it works — we just don't have enough reliable data.
How safe is it?
Well-documented data
Topical sulfur is generally well tolerated, but oral forms like this one are less studied. Oral sulfur can cause diarrhea and intestinal irritation because bacteria in your colon convert it to sulfide and sulfate, which can irritate the gut.
There's one case report of a person who developed a serious acid-base imbalance (metabolic acidosis) after taking very large amounts — about 250 grams over six days — though underlying kidney and blood sugar problems likely played a role. The safety data suggests it's possibly safe in pregnancy and lactation, but because oral sulfur hasn't been well researched, you should talk with your doctor or pharmacist before using it while pregnant or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for the sulfur we could check. We hold no data for methylsulfonylmethane (MSM).
Check your medications on this page before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This supplement may help with scabies or dandruff, though the evidence is limited. Because oral sulfur can cause stomach upset and we don't have extensive safety data for it, this is one to run by your pharmacist first — especially if you have kidney problems, diabetes, or are pregnant or nursing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about M-S-M Sulfur 1,000 mg, straight from the product label.
| Brand | Carlson |
|---|---|
| Barcode (UPC) | 088395087219 |
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 337547 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for M-S-M Sulfur 1,000 mg by Carlson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sulfur | 330 mg | -- |
| Methylsulfonylmethane | 1000 mg | -- |
Other ingredients: Hypromellose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Mineral depletion in the soil and mineral loss through food preparation make it difficult for us to get an adequate amount of sulfur. Carlson MSM Sulfur from OptiMSM is a highly bioavailable form of sulfur that's found in many of our body's tissues. It supports joint health by helping to maintain healthy connective tissue and is an important component of skin, hair, and nail proteins.
OptiMSM
Formulation
Gluten-free No artificial preservatives
Potency & quality guaranteed An FDA Regulated facility
Superior bioavailability Joint function Connective tissue support Healthy Skin
Seals/Symbols
Impact Collective Reduced Plastic Impact
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults: take one capsule up to six times daily at mealtime.
Storage
Keep bottle tightly closed. Store away from heat and moisutre.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
OptiMSM is a registered trademark of Balchem Corporation or its subsidiaries.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
M-S-M Sulfur 1,000 mg by Carlson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in M-S-M Sulfur 1,000 mg by Carlson
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Methylsulfonylmethane
- › Sulfur
Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.
M-S-M Sulfur 1,000 mg by Carlson Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in M-S-M Sulfur 1,000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for M-S-M Sulfur 1,000 mg, from the product label.
Carlson
See all Carlson products- Name
- Carlson Div. of J.R. Carlson Laboratories, Inc.
- City
- Arlington Heights
- State
- IL
- ZipCode
- 60004
- Phone Number
- 888-234-5656
- Web Address
- carlsonlabs.com
M-S-M Sulfur 1,000 mg by Carlson: Common Questions
Does M-S-M Sulfur 1,000 mg by Carlson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
Will this help my acne?
What side effects should I watch for?
Is this the same as topical sulfur products?
Can I take this with my other supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if M-S-M Sulfur 1,000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind M-S-M Sulfur 1,000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
M-S-M Sulfur 1,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sulfur 17 references
- Blum, J. E. and Coe, F. L. Metabolic acidosis after sulfur ingestion. N Engl J Med 1977;297(16):869-70. PubMed
- Roos, T. C., Alam, M., Roos, S., Merk, H. F., and Bickers, D. R. Pharmacotherapy of ectoparasitic infections. Drugs 2001;61(8):1067-88. PubMed
- Diaz, M., Cazorla, D., and Acosta, M. [Efficacy, safety and acceptability of precipitated sulphur petrolatum for topical treatment of scabies at the city of Coro, Falcon State, Venezuela]. Rev Invest Clin 2004;56(5):615-22.
- Schmiedel, V. and Klein, P. A complex homeopathic preparation for the symptomatic treatment of upper respiratory infections associated with the common cold: An observational study. Explore (NY) 2006;2(2):109-14. PubMed
- Weiser, M., Gegenheimer, L. H., and Klein, P. A randomized equivalence trial comparing the efficacy and safety of Luffa comp.-Heel nasal spray with cromolyn sodium spray in the treatment of seasonal allergic rhinitis. Forsch Komplementarmed 1999;6(3):142- PubMed
- FDA OTC ingredients list, April 2010. Available at: www.fda.gov/downloads/AboutFDA/CentersOffices/CDER/UCM135691.pdf (accessed 2/7/15).
- Leyden, J. J., McGinley, K. J., Mills, O. H., Kyriakopoulos, A. A., and Kligman, A. M. Effects of sulfur and salicylic acid in a shampoo base in the treatment of dandruff: a double-blind study using corneocyte counts and clinical grading. Cutis 1987;39(6)
- Trumbore, M. W., Goldstein, J. A., and Gurge, R. M. Treatment of papulopustular rosacea with sodium sulfacetamide 10%/sulfur 5% emollient foam. J Drugs Dermatol 2009;8(3):299-304.
- Pelle, M. T., Crawford, G. H., and James, W. D. Rosacea: II. Therapy. J Am Acad Dermatol 2004;51:499-512.
- Blom I, Hornmark AM. Topical treatment with sulfur 10 per cent for rosacea. Acta Derm Venereol 1984;64:358-9. DOI
- Gupta, A. K. and Nicol, K. The use of sulfur in dermatology. J Drugs Dermatol 2004;3(4):427-31.
- Akhavan, A. and Bershad, S. Topical acne drugs: review of clinical properties, systemic exposure, and safety. Am J Clin Dermatol 2003;4(7):473-92.
- Wilkinson RD, Adam JE, Murray JJ, Craig GE. Benzoyl peroxide and sulfur: foundation for acne management. Can Med Assoc J 1966;95(1):28-9.
- Food and Drug Administration. Classification of benzoyl peroxide as safe and effective and revision of labeling to drug facts format; topical acne drug products for over-the-counter human use; final rule. Federal Register 2010;75(42):9767-77.
- Lin, A. N., Reimer, R. J., and Carter, D. M. Sulfur revisited. J Am Acad Dermatol 1988;18(3):553-8.
- Goszcz, A., Kostka-Trabka, E., Grodzinska, L., et al. [The effect of treatment with sulphur water from the spring in Wieslaw in Busko-Solec on levels of lipids, the fibrinolytic system and thrombogenic platelet function in patients with arteriosclerosis].
- Contoli M, Gnesini G, Forini G, et al. Reducing agents decrease the oxidative burst and improve clinical outcomes in COPD patients: a randomised controlled trial on the effects of sulphurous thermal water inhalation. ScientificWorldJournal. 2013 Dec 23;20 PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC