No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maca 500 mg Ingredients & Drug Interactions

by Natrol

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Maca 500 mg is a dietary supplement by Natrol with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maca 500 mg by Natrol

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: maca extract at 500 mg per capsule. Maca is a root plant used traditionally in South American cooking and traditional medicine.

The supplement also contains several inactive ingredients — maltodextrin, gelatin, silicon dioxide, and magnesium stearate — which are fillers and capsule materials.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: promote libido and sexual health function.
  • We looked for evidence on: Sexual desire, Male infertility, Antidepressant-induced sexual dysfunction, Age-related testosterone deficiency, erectile dysfunction, sexual performance — and 1 related terms.
  • The closest evidence on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction (Natural Medicines).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Sexual desire, Age-related testosterone deficiency, Male infertility.

The evidence for maca isn't established in our data. The facts list a number of uses — from sexual function to bone health to athletic performance — but all of them are rated as insufficient reliable evidence.

That doesn't mean maca doesn't work; it means the scientific evidence we hold on file isn't robust enough to be confident either way. If you're thinking about it for a specific reason, ask your doctor what the current research shows for that use.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca is generally well tolerated when eaten as a food, but long-term safety as a supplement hasn't been studied thoroughly. Fresh, uncooked maca may cause stomach pain in some people.

The safety data advises against use during pregnancy and breastfeeding — there isn't enough reliable information about either one to know it's safe, so avoid it during those times.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for maca extract in our data. That said, run your medications through the checker on this page before you start, and let your doctor or pharmacist know you're taking it — especially if you're on blood thinners, blood pressure drugs, or any hormonal therapy.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Maca has been used as a food for centuries and shows no known drug interactions, which is a good starting point. But the evidence for what it actually does is still incomplete, and long-term supplement safety hasn't been firmly established.

Talk with your doctor or pharmacist about whether it makes sense for what you're trying to address — and definitely check with them before taking it if you're pregnant, breastfeeding, or on any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maca 500 mg, straight from the product label.

Brand Natrol
Barcode (UPC) 047469161569
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 203342
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maca 500 mg by Natrol, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
047469161569
IngredientAmount% DV
Maca extract500 mg--

Other ingredients: Maltodextrin, Gelatin, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Natrol Maca 500mg helps promote libido and sexual health function. Maca is a tuberous root that grows high in the Andes Mountains of South America. Native Peruvians traditionally used Maca for energy, stamina, as an aphrodisiac, and for its fertility-enhancing properties.

Men's health

Precautions

Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition or are taking prescription drugs.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

ITEM: 16156.911 F: 3000113 L: 2008976-17222

General Statements

Supports sexual vitality Promotes improved fertility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule, one time daily, with a meal.

Formulation

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors or flavors, added sugar or preservatives

See for yourself

Maca 500 mg by Natrol label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maca 500 mg by Natrol

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Maca extract

No known
interactions
500 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca extract monograph & interactions

Other (inactive) ingredients: Maltodextrin, Gelatin, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maca 500 mg by Natrol Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maca 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maca 500 mg, from the product label.

Natrol

See all Natrol products
Name
Natrol LLC
City
Chatsworth
State
CA
ZipCode
91311
Phone Number
1-800-262-8765
Web Address
www.natrol.com
Pharmacist Counseling Corner

Maca 500 mg by Natrol: Common Questions

Does Maca 500 mg by Natrol interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maca 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maca 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
The safety data advises against it. There isn't enough reliable information to know maca is safe in either pregnancy or breastfeeding, so you'll want to skip it during those times and talk with your doctor or midwife.
Does maca actually work?
The evidence in our data is insufficient to say for sure. Maca is used for several things — sexual function, energy, bone health — but the scientific evidence we hold on file isn't strong enough to be confident about any of them yet.
What are the side effects?
Maca is generally well tolerated, but fresh, uncooked maca can cause stomach pain. As a supplement, long-term safety hasn't been thoroughly studied, so we don't have a full picture of rare or longer-term effects.
Is this safe to take long-term?
Maca has a long history as a food, which is reassuring. But supplement safety over the long haul hasn't been studied formally, so you'll want to check in with your doctor about how long you plan to take it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maca 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maca 500 mg label
Go deeper

The Full Monographs Behind Maca 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maca 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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