No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maca 500 mg Ingredients & Drug Interactions

by Whole Foods Market

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Maca 500 mg is a dietary supplement by Whole Foods Market with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maca 500 mg by Whole Foods Market

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: maca, a root traditionally used in South American cuisine and herbal practice. The capsule also holds modified vegetable cellulose, an inactive ingredient that serves as the capsule material.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Maca product and its label doesn't state a use — see Maca's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for maca is limited. The data we hold rates it as having insufficient reliable evidence for amenorrhea (absent menstruation), anemia of chronic disease, sexual dysfunction related to antidepressants, athletic performance, and osteoporosis.

That means the studies so far haven't been strong or consistent enough to say whether it works for these uses.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca is generally well tolerated when used as a food, but long-term safety as a supplement hasn't been studied in depth. The main concern we know about is stomach pain — fresh, uncooked maca may cause it.

Because there isn't enough safety data in supplement amounts, avoid maca during pregnancy. The same goes for breastfeeding: there isn't enough reliable information to know whether it's safe.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That's not a guarantee none exist — just that the data we hold doesn't flag any concerns.

Check your exact medications with the search tool on this page, or confirm with your own pharmacist or doctor to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Maca is generally well tolerated in supplement form, and it doesn't interact with medications we've documented. But the evidence for what it actually does is thin, and safety data in long-term use is sparse.

If you're pregnant or nursing, the data suggests you skip it. Talk it over with your doctor or pharmacist before you start, especially if you have stomach sensitivity.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maca 500 mg, straight from the product label.

Brand Whole Foods Market
Barcode (UPC) 099482455521
Net contents 90 Vegan Capsule(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 277441
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maca 500 mg by Whole Foods Market, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegan Capsule(s)
Maximum serving Sizes:
1 Vegan Capsule(s)
Servings per container
90
UPC/BARCODE
099482455521
IngredientAmount% DV
Maca500 mg--

Other ingredients: Modified Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Note: If you are pregnant, nursing, have any health condition or are taking any medications, consult your health care practitioner before using this product.

Tamper evident, use only if seal is intact.

Keep out of reach of children.

Produced in a facility that processes tree nuts, shellfish and soy.

Formulation

Contains no artificial colors, flavors or preservatives.

Vegan

Adaptogenic herb Supports healthy energy & stamina levels

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

K Parve K-1604 GMP Good Manufacturing Practice

Formula

K Parve K-1604

Individual herbs & blends

500 mg of Raw & Gelatinized Maca Root

General Statements

Please recycle

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule, 1-2 times per day.

Brand IP Statement(s)

Copyright 2015 Whole Foods Market IP, LP

See for yourself

Maca 500 mg by Whole Foods Market label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maca 500 mg by Whole Foods Market

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegan Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Maca

No known
interactions
500 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca monograph & interactions

Other (inactive) ingredients: Modified Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maca 500 mg by Whole Foods Market Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maca 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maca 500 mg, from the product label.

Whole Foods Market

See all Whole Foods Market products
Name
Whole Foods Market
Street Address
550 Bowie Street
City
Austin
State
TX
ZipCode
78703
Web Address
www.wholefoodsmarket.com
Pharmacist Counseling Corner

Maca 500 mg by Whole Foods Market: Common Questions

Does Maca 500 mg by Whole Foods Market interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maca 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maca 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is maca safe during pregnancy?
The safety data advises against it. There isn't enough reliable information on maca supplements in pregnancy, so avoid them if you're pregnant or planning to be.
Is maca safe while breastfeeding?
There isn't enough reliable information to know whether it's safe while nursing. Talk with your doctor or pharmacist about whether to take it if you're breastfeeding.
Can maca cause side effects?
Fresh, uncooked maca may cause stomach pain. The supplement form hasn't been studied long term, so other side effects aren't well documented.
Does maca actually work for low energy or sex drive?
The evidence isn't established in the data we hold. Studies so far haven't been strong or consistent enough to say it works for these or other common uses.
What is maca?
Maca is a root plant from South America, traditionally used in food and herbal practice. It's been marketed for energy, fertility, and sexual function, but the evidence is limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maca 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maca 500 mg label
Go deeper

The Full Monographs Behind Maca 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maca 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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