No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

MACA plus Pygeum Ingredients & Drug Interactions

by Wonder Laboratories

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

MACA plus Pygeum is a dietary supplement by Wonder Laboratories with 2 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of MACA plus Pygeum by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: pygeum extract and maca extract. Pygeum is traditionally used for prostate health, while maca is a plant-based ingredient used for general wellness.

The capsules also contain inactive ingredients — gelatin, vegetable cellulose, vegetable magnesium stearate, and silica — which serve as fillers and binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Benign prostatic hyperplasia (BPH) — rated "Likely Effective" (Pygeum) (Natural Medicines).

The evidence behind these ingredients is mixed. Pygeum extract is likely effective for benign prostatic hyperplasia (BPH), a common prostate condition in older men.

For other uses listed — Alzheimer disease, malaria, sexual desire, and psychosis — the evidence isn't established in the data we hold. Maca extract shows insufficient evidence for the conditions studied so far, which include amenorrhea (irregular menstrual periods), anemia, antidepressant-induced sexual dysfunction, athletic performance, and osteoporosis.

If you're considering this product for a specific health goal, it's worth talking with your doctor about whether the evidence supports that use.

The evidence, ingredient by ingredient Pygeum Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated as used short-term, but long-term safety data are limited. Pygeum has been linked to nausea and abdominal pain in some studies, though the rates were similar to placebo.

Maca, especially if uncooked or fresh, may cause stomach pain in some people. Neither ingredient has enough safety data to support use during pregnancy or breastfeeding — the safety data advises against both.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Pygeum Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product. Still, talk with your doctor or pharmacist about your exact medications before you begin, since our data has limits and new information can emerge.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

MACA plus Pygeum is a reasonable choice if you're interested in pygeum for prostate health and want a multi-ingredient product. No interactions are documented for the ingredients we checked, but long-term safety data are sparse for both.

If you're pregnant, breastfeeding, or take any medications, confirm with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MACA plus Pygeum, straight from the product label.

Brand Wonder Laboratories
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 262508
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Kosher, Adult Male (18-50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MACA plus Pygeum by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Pygeum extract40 mg--
Maca extract500 mg--

Other ingredients: Gelatin, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 capsule twice daily.

Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Nutritionally supports healthy prostate function

Gluten free

Made in USA

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Reorder #0511

Formula

Now with 40% more MACA

Ko Kosher Service

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Ko Kosher Service

See for yourself

MACA plus Pygeum by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in MACA plus Pygeum by Wonder Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pygeum extract

No known
interactions
40 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum extract monograph & interactions

Maca extract

No known
interactions
500 mg per serving Form: Glucosinolates

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca extract monograph & interactions

Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

MACA plus Pygeum by Wonder Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in MACA plus Pygeum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for MACA plus Pygeum, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

MACA plus Pygeum by Wonder Laboratories: Common Questions

Does MACA plus Pygeum by Wonder Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in MACA plus Pygeum. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
MACA plus Pygeum contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pygeum extract used for?
Pygeum extract is used for prostate health, particularly for benign prostatic hyperplasia (BPH) — a common condition in older men where the prostate enlarges. It's the main ingredient in this product with solid evidence behind it.
What does maca extract do?
Maca extract is a plant-based ingredient used for general wellness, but the evidence for specific health claims — like improving sexual function, athletic performance, or bone health — isn't established in the data we hold. It's sometimes used as a traditional food supplement.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against both ingredients during pregnancy and breastfeeding because there isn't enough reliable safety information. Talk with your doctor or pharmacist before taking this product if you're pregnant, planning to become pregnant, or breastfeeding.
What side effects might I experience?
Nausea, abdominal pain, and stomach pain are the side effects reported in studies, though they occurred at rates similar to placebo in pygeum research. Most people tolerate these ingredients well short-term, but long-term safety data are limited.
Is this safe to take long-term?
Long-term safety data are sparse for both pygeum and maca as supplements. Both are generally well tolerated in short-term studies, but we don't have strong evidence for safety over months or years. Talk with your doctor about how long you plan to take it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MACA plus Pygeum is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MACA plus Pygeum label
Sources

Sources & How We Checked

MACA plus Pygeum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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