No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Mastica Ingredients & Drug Interactions

by Allergy Research Group

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Mastica is a dietary supplement by Allergy Research Group with 1 active ingredient. Its ingredients are commonly taken for indigestion and stomach upset, stomach ulcers and h. pylori support, oral and gum health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Mastica by Allergy Research Group

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Mastica contains one active ingredient: mastic, a resin from the mastic tree. It's used traditionally for digestive health.

The capsule itself is made from inactive ingredients — a plant-based cellulose shell, microcrystalline cellulose, magnesium stearate, and silicon dioxide — which are standard capsule fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and oral wellness support.
  • We looked for evidence on: Dyspepsia, Helicobacter pylori, Peptic ulcers, Halitosis, Periodontitis, GERD — and 1 related terms.
  • The strongest evidence on file: Mastic is rated "Possibly Effective" for Dyspepsia (Natural Medicines).
  • Also on file: Mastic is rated "Insufficient Reliable Evidence To Rate" for Helicobacter pylori, Peptic ulcers, Periodontitis, Halitosis.

Mastic is possibly effective for dyspepsia (indigestion and upset stomach). For brittle nails, fatty liver disease, and cancer prevention, the evidence isn't established in our data — there isn't enough reliable research yet to say whether it works for those uses.

The evidence, ingredient by ingredient Mastic

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mastic seems to be well tolerated when taken by mouth in the amounts used in supplements, though safety data are limited. The most common side effects reported are nausea, diarrhea, and constipation — though these have been rare.

We don't have enough safety information to recommend mastic supplements during pregnancy or while breastfeeding; talk with your doctor or pharmacist before using it at that time.

Side effects, ingredient by ingredient Mastic

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, run your exact medications through the checker on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Mastica is a reasonable choice if you're looking for something possibly effective for indigestion. It's generally well tolerated, and no drug interactions are documented.

If you're pregnant, breastfeeding, or take any medications, check with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mastica, straight from the product label.

Brand Allergy Research Group
Barcode (UPC) 713947736603
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 258260
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mastica by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
713947736603
IngredientAmount% DV
Pistacia lentiscus var. Chia1 Gram(s)--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Chios Gum Mastic (also known as Mastiha) is the resinous material obtained from the Pistacia lentiscus tree, grown on the island of Chios in Greece. Authentic Chios mastiha provided by the Chios Mastiha Growers Association (CMGA).

Authentic Chios Mastiha

Suggested/Recommended/Usage/Directions

Suggested use As a dietary supplement, 1 or 2 capsules two times daily between meals, or as directed by a healthcare practitioner.

Formulation

Variations in product color may occur.

Hypoallergenic

Storage

Keep in a cool, dry place, tightly capped.

FDA Statement of Identity

Dietary Supplement

See for yourself

Mastica by Allergy Research Group label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mastica by Allergy Research Group

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Pistacia lentiscus var. Chia

No known
interactions
1 Gram(s) per serving

Mastic is a resin from the mastic tree that has a long history of use for digestive complaints and oral health. Some small studies suggest it may help...

Pistacia lentiscus var. Chia monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mastica by Allergy Research Group Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Mastica. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Mastica, from the product label.

Allergy Research Group

See all Allergy Research Group products
Name
Allergy Research Group
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800-545-9960
Web Address
www.allergyresearchgroup.com
Pharmacist Counseling Corner

Mastica by Allergy Research Group: Common Questions

Does Mastica by Allergy Research Group interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Mastica. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Mastica contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is mastic, and where does it come from?
Mastic is a resin from the mastic tree (Pistacia lentiscus). It's been used traditionally in Mediterranean cultures for digestive support and has been studied in supplement form.
Will this help my indigestion?
Mastic is possibly effective for dyspepsia (indigestion and upset stomach), so it may help — but the evidence is still developing. Talk to your pharmacist about whether it's right for your situation.
What side effects should I watch for?
Nausea, diarrhea, and constipation have been rarely reported with mastic. Most people tolerate it well. If you notice any of these, stop and let your pharmacist know.
Is it safe to take while pregnant or breastfeeding?
No — there isn't enough safety information to recommend mastic supplements during pregnancy or breastfeeding. Talk with your doctor or pharmacist about your options.
Does Mastica have any fillers?
The capsule contains standard inactive ingredients: cellulose (the capsule shell), microcrystalline cellulose, magnesium stearate, and silicon dioxide. These are common binders and flow agents in capsules.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mastica is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mastica label
Go deeper

The Full Monographs Behind Mastica’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Mastica's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mastic 5 references
  1. Kaliora, A. C., Stathopoulou, M. G., Triantafillidis, J. K., Dedoussis, G. V., and Andrikopoulos, N. K. Chios mastic treatment of patients with active Crohn's disease. World J Gastroenterol. 2-7-2007;13(5):748-753. PubMed
  2. Dabos, K. J., Sfika, E., Vlatta, L. J., and Giannikopoulos, G. The effect of mastic gum on Helicobacter pylori: a randomized pilot study. Phytomedicine. 2010;17(3-4):296-299. PubMed
  3. Dabos, K. J., Sfika, E., Vlatta, L. J., Frantzi, D., Amygdalos, G. I., and Giannikopoulos, G. Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. J Ethnopharmacol. 2-3-20 PubMed
  4. Hazan Z, Adamsky K, Lucassen A, Levin LA. A first-in-human phase 1 randomized single and multiple ascending dose study of RPh201 in healthy volunteers. Clin Pharmacol Drug Dev. 2020;9(3):366-74. PubMed
  5. Moraschini V, Kischinhevsky ICC, Calasans-Maia MD, et al. Ineffectiveness of ozone therapy in nonsurgical periodontal treatment: a systematic review and metaanalysis of randomized clinical trials. Clin Oral Investig 2020;24(6):1877-1888. PubMed

See these in context on the Mastic monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring