No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maximum Strength Biotin 5,000 mcg Ingredients & Drug Interactions

by Nature Made

Softgel Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Maximum Strength Biotin 5,000 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maximum Strength Biotin 5,000 mcg by Nature Made

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin your body uses to break down food and convert it into energy. You're getting 5,000 micrograms per softgel capsule.

The inactive ingredients are soybean oil, gelatin, glycerin, yellow beeswax, water, soy lecithin, and added colors — these are the capsule and carrier materials that hold the biotin stable.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: hair, skin and nails support for biotin deficiency.
  • We looked for evidence on: Biotin deficiency, Brittle nails, Hair loss, Skin health.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for biotin deficiency — if you're actually low in this vitamin, supplementing will help. For multiple sclerosis (MS) and seborrheic dermatitis (a scalp condition), the evidence suggests it's probably not effective.

For alopecia areata (patchy hair loss), there isn't enough reliable evidence yet to say either way.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body clears excess amounts through urine. High-dose biotin has rarely been linked to mild diarrhea; one case report described a French traveler who developed fluid around the heart and lungs after taking 10 mg daily for 2 months alongside other supplements and a heart medication, though it's unclear whether biotin was the cause.

The safety data advises checking with your doctor before taking high-dose biotin supplements — amounts from food and prenatal vitamins are fine on their own.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't guarantee none exist, so run your exact medications through the search tool on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have biotin deficiency, this supplement will help. For other reasons — hair, skin, or nerve conditions — the evidence doesn't support it.

Since this is a high-dose product, talk it over with your doctor or pharmacist before starting, especially if you take other medications or supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maximum Strength Biotin 5,000 mcg, straight from the product label.

Brand Nature Made
Barcode (UPC) 031604029180
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 179953
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maximum Strength Biotin 5,000 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
031604029180
IngredientAmount% DV
Biotin5000 mcg1667%

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Soy Lecithin, Colors added

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

List No. 2918 L201 Cat. A611 5A044

General Statements

Value size #1 pharmacist recommended

Maximum strength for adults diagnosed with very low levels of biotin

Biotin may also help support healthy hair, skin and nails for those that are biotin deficient. Strength levels of Biotin R Regular 300 mcg or below E Extra about 300 mcg up to 2,500 mcg M Maximum about 2,500 mcg up to 5,000 mcg M Maximum 5,000 mcg - Helps restore healthy levels of biotin in adults with very low levels, as diagnosed by their health care professional using appropriate biomarkers. For more information, visit NaturenMade.com

USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org. For those with biotin deficiency. Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

Seals/Symbols

USP Dietary Supplement Verified

Formula

Maximum Strength Biotin 5,000 mcg

Nature Made Maximum Strength Biotin provides 5000 mcg of biotin, a B vitamin that supports carbohydrate, protein and fat metabolism.

Contains: Soy.

FDA Statement of Identity

Dietary Supplement

Formulation

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Suggested/Recommended/Usage/Directions

Suggested use: Consult your health care professional before use. Take one softgel daily, with a meal. For easier swallowing, take with water before and during ingestion.

Precautions

Caution: Do not exceed one softgel daily unless recommended by a health care professional.

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Contains: Soy.

Storage

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Maximum Strength Biotin 5,000 mcg by Nature Made label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maximum Strength Biotin 5,000 mcg by Nature Made

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Biotin

No known
interactions
5000 mcg per serving Form: Vitamin B7

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Soy Lecithin, Colors added. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maximum Strength Biotin 5,000 mcg by Nature Made Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maximum Strength Biotin 5,000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maximum Strength Biotin 5,000 mcg, from the product label.

Nature Made

See all Nature Made products
Name
Nature Made Nutritional Products
City
Mission Hills
State
CA
ZipCode
91346-9606
Phone Number
1-800-276-2878
Web Address
www.NatureMade.com
Pharmacist Counseling Corner

Maximum Strength Biotin 5,000 mcg by Nature Made: Common Questions

Does Maximum Strength Biotin 5,000 mcg by Nature Made interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maximum Strength Biotin 5,000 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maximum Strength Biotin 5,000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe during pregnancy and breastfeeding?
Yes — biotin is rated likely safe during pregnancy and lactation. That said, the safety data suggests checking with your doctor before taking high-dose supplements specifically. Normal dietary amounts and standard prenatal vitamins are appropriate.
What is biotin actually for?
Biotin is a B vitamin that helps your body break down and use food for energy. It's definitely effective if you have a biotin deficiency — a true shortage of the vitamin. For hair, skin, or nerve health, the evidence doesn't support it.
Can this much biotin cause side effects?
Side effects are rare. High-dose biotin has occasionally caused mild diarrhea. One case report described a person who developed inflammation around the heart and lungs, but it's unclear whether biotin was responsible, and no similar cases have been reported since.
Will this help my hair loss or thinning?
The evidence doesn't establish that biotin works for hair loss or thinning. It's likely effective only if you actually have a biotin deficiency — a real shortage of the vitamin.
Do I need to take this with food?
The product facts don't cover how or when to take it. Check the label instructions or ask your pharmacist for the best way to use this softgel.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maximum Strength Biotin 5,000 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maximum Strength Biotin 5,000 mcg label
Go deeper

The Full Monographs Behind Maximum Strength Biotin 5,000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maximum Strength Biotin 5,000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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