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Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Zinc is a mineral that is essential for the proper functioning of the human body. It is involved in many important physiological processes, including immune system function, wound healing, taste, and smell. Zinc is found in a variety of foods, including meat, seafood, and whole grains, and it is also available as a dietary supplement. Zinc supplements may be used to treat or prevent zinc deficiency, which can occur due to certain medical conditions, such as gastrointestinal disorders, alcohol abuse, and certain medications. Zinc supplements may also be used for other purposes, such as to boost the immune system, improve acne, and reduce the severity and duration of colds. There are several different forms of zinc supplements available, including zinc gluconate, zinc acetate, and zinc sulfate. The most common form of zinc supplements is zinc gluconate, which is well absorbed and is less likely to cause stomach-related side effects than other forms of zinc.

Boron is a trace mineral that is found in a variety of foods, including fruits, vegetables, nuts, and legumes. It is also available as a dietary supplement. Boron is thought to play a role in bone health, as it may help the body metabolize calcium, magnesium, and phosphorus. Some preliminary research also suggests that boron may have anti-inflammatory effects and may help to improve cognitive function. However, more research is needed to confirm these potential benefits. It is important to note that boron is not an essential nutrient and deficiency is rare. The recommended dietary allowance (RDA) for boron is not established, however, the safe upper limit is 20mg/day. Taking high doses of boron can cause skin irritation, nausea, vomiting, and diarrhea. There are several patented forms of boron available in dietary supplements, such as Albion Bororganic Glycine.