Megasorb CoQ-10 30 mg Ingredients & Drug Interactions
by Solgar
What is this page for?
First and foremost: checking Megasorb CoQ-10 30 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Megasorb CoQ-10 30 mg is a dietary supplement by Solgar with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Megasorb Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Megasorb CoQ-10 30 mg by Solgar
Ask about any prescription or over-the-counter medication and we check it for interactions with Megasorb CoQ-10 30 mg by Solgar — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Megasorb CoQ-10 30 mg by Solgar
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Megasorb CoQ-10 contains one active ingredient: coenzyme Q10 (a compound your body makes naturally and uses for energy production and antioxidant protection). This product delivers 30 mg per softgel capsule.
The inactive ingredients are rice bran oil, gelatin, vegetable glycerin, soy lecithin, paprika, and titanium dioxide color.
Does it work?
Moderate evidence
CoQ10 is likely effective for coenzyme Q10 deficiency. It's possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy.
The evidence for these uses comes from clinical research, though results have been mixed for some conditions like blood pressure control.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults when used as directed. Gastrointestinal side effects — such as nausea, diarrhea, heartburn, and appetite loss — occur in less than 1% of people.
Headache, dizziness, and insomnia have been reported, and skin itching or allergic rash is rare. During pregnancy, there isn't enough reliable safety data, so it's best to avoid this product unless your doctor advises otherwise.
For breastfeeding, safety hasn't been well studied; talk with your doctor before taking it.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you're on warfarin or other blood thinners, chemotherapy drugs (especially alkylating agents like cyclophosphamide), or blood pressure medications. CoQ10 can interfere with how these drugs work.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 may help with heart function, migraines, or nerve pain, and it's generally well tolerated. But if you take warfarin, chemotherapy, or blood pressure medication, you need to check with your doctor or pharmacist first — the interactions are real and could affect how those drugs work.
Your healthcare provider can help you decide if this supplement fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Megasorb CoQ-10 30 mg, straight from the product label.
| Brand | Solgar |
|---|---|
| Barcode (UPC) | 033984009455 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2020 |
| DSLD ID | 217627 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Megasorb CoQ-10 30 mg by Solgar, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Megasorb Coenzyme Q-10 | 30 mg | -- |
Other ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Paprika, Titanium Dioxide color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Coenzyme Q-10 is a natural antioxidant which plays several highly useful roles in the body, including support for heart health and the production of energy in cells. CoQ-10 has also been identified as important for those taking Statin medications as it can replace what they may deplete.
New smaller softgel Easier to swallow Enhanced absorption
Gluten, wheat & dairy free
Free of: Gluten, wheat, dairy, yeast, sugar, sodium, artificial flavor, sweetener and preservatives.
Formula
MEGASORB CoQ-10 is offered in a base of rice bran oil to promote and enhance absorption of this fat-soluble, active ingredient.
Precautions
CoQ-10 is not intended as a substitute for Statin therapy. Do not discontinue use of prescribed medications while taking CoQ-10.
Solgar since 1947
If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement.
Discontinue use and consult your healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
Do not use if outer bottle seal is missing or damaged.
Brand IP Statement(s)
2013 Solgar, Inc.
KANEKAQ10 Kaneka and KanekaQ10 are registered trademarks of the Kaneka Corporation.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement for adults, take one (1) softgel up to two times daily, preferably with meals, or as directed by a healthcare practitioner.
Storage
Store at room temperature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Megasorb CoQ-10 30 mg by Solgar label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Megasorb CoQ-10 30 mg by Solgar
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Megasorb Coenzyme Q-10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Megasorb Coenzyme Q-10 monograph & interactionsOther (inactive) ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Paprika, Titanium Dioxide color. These complete the product’s ingredient list but are not active constituents.
Megasorb CoQ-10 30 mg by Solgar Drug Interactions
HelloPharmacist Interaction Report
Megasorb CoQ-10 by Solgar does interact with medications, mainly through its single active ingredient, coenzyme Q10.
The most serious concern is with warfarin (Coumadin), a blood thinner — CoQ10 can reduce warfarin's anticoagulant effects, and four cases of decreased warfarin efficacy have been reported. This is a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 also has Moderate interactions with alkylating chemotherapy agents (such as cyclophosphamide). Because CoQ10 is an antioxidant, it may theoretically protect tumor cells from drugs that work by generating free radicals, reducing the chemotherapy's effectiveness.
Additionally, CoQ10 can cause Minor additive effects with blood pressure medications (antihypertensives). Some research shows CoQ10 can lower blood pressure on its own, so combining it with drugs that do the same could lower your pressure more than intended.
Altogether, these interactions span 198 individual medications. Use the interaction checker below to search your exact medications before starting this product, and run any results past your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Megasorb CoQ-10 30 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Megasorb CoQ-10 30 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Megasorb CoQ-10 30 mg interact with drugs. Each result below shows which ingredient is responsible. Megasorb Coenzyme Q-10
AltretamineHexalen
How Altretamine interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Megasorb Coenzyme Q-10 + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Megasorb Coenzyme Q-10 + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Megasorb CoQ-10 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Megasorb CoQ-10 30 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Megasorb Coenzyme Q-10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Megasorb CoQ-10 30 mg, from the product label.
Solgar
See all Solgar products- Name
- Solgar, Inc.
- Street Address
- 500 Willow Tree Road
- City
- Leonia
- State
- NJ
- ZipCode
- 07605
- Phone Number
- 1-877-765-4274
- Web Address
- www.solgar.com
Megasorb CoQ-10 30 mg by Solgar: Common Questions
Does Megasorb CoQ-10 30 mg by Solgar interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does CoQ10 actually do in my body?
Can I take this if I'm pregnant?
What side effects should I watch for?
Will this help my migraines?
Is this dose high enough to work?
Can I take this while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Megasorb CoQ-10 30 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Megasorb CoQ-10 30 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Megasorb CoQ-10 30 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC