Meta-Sitosterol 2.0 Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking Meta-Sitosterol 2.0 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Meta-Sitosterol 2.0 is a dietary supplement by Metagenics with 5 active ingredients. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Meta-Sitosterol 2.0 by Metagenics
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 5 of its 5 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.
Why this rating?
- None of the 1 matched ingredient has a documented medication interaction on file.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Meta-Sitosterol 2.0, straight from the product label.
| Brand | Metagenics |
|---|---|
| Net contents | 90 Tablet(s) |
| Market status | Off market |
| Date entered into DSLD | Dec 22, 2019 |
| DSLD ID | 209701 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Qualified Health, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Meta-Sitosterol 2.0 by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Folate | 800 mcg, 267 mcg | 200%, 67% |
| Stigmasterol | 275 mg, 92 mg | -- |
| Campesterol | 500 mg, 167 mg | -- |
| Beta-Sitosterol | 1000 mg, 333 mg | -- |
| other Plant Sterols | 350 mg, 117 mg | -- |
Other ingredients: Plant Sterol Complex, Microcrystalline Cellulose, Croscarmellose Sodium, Cellulose, Stearic Acid, Silica, Calcium L-5-Methyltetrahydrofolate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Meta-Sitosterol 2.0 is a naturally derived vegetable preparation featuring enhanced levels of a balanced concentrate of plant sterols--2 grams per day--which may help to maintain healthy blood cholesterol levels already within the normal range. The National Institutes of Health recommends a healthy diet, along with the consumption of 2 grams of plant sterols daily, to promote cardiovascular health. Also features the active, preferred form of folate (L-5-methyltetrahydrofolate) to support healthy homocysteine metabolism and cardiovascular health.
Plant sterol complex for support of healthy cholesterol levels
Suggested/Recommended/Usage/Directions
Directions: Take one tablet with each meal or as directed by your healthcare practitioner.
Formulation
This product is gluten-free and vegetarian.
This product is gluten-free and vegetarian.
Precautions
Caution: Keep out of the reach of children.
Contains: Soy.
Seals/Symbols
GF Certified gluten-free
Storage
Do not refrigerate (Refrigeration may cause moisture condensation).
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Practitioner exclusive
Brand IP Statement(s)
U.S. Patent Nos. 5,997,915; 6,254,904. Metafolin is a registered trademark of Merck KGaA, Darmstadt Germany
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Meta-Sitosterol 2.0 by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Meta-Sitosterol 2.0 by Metagenics
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Folate
Stigmasterol
Campesterol
Beta-Sitosterol
No knowninteractions
Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...
Beta-Sitosterol monograph & interactionsOther Plant Sterols
Other (inactive) ingredients: Plant Sterol Complex, Microcrystalline Cellulose, Croscarmellose Sodium, Cellulose, Stearic Acid, Silica, Calcium L-5-Methyltetrahydrofolate. These complete the product’s ingredient list but are not active constituents.
Meta-Sitosterol 2.0 by Metagenics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Meta-Sitosterol 2.0. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Meta-Sitosterol 2.0, from the product label.
Metagenics
See all Metagenics products- Name
- Metagenics
- City
- Gig Harbor
- State
- WA
- ZipCode
- 98332
- Phone Number
- 800 692 9400
- Web Address
- metagenics.com
Meta-Sitosterol 2.0 by Metagenics: Common Questions
Does Meta-Sitosterol 2.0 by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Meta-Sitosterol 2.0 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Meta-Sitosterol 2.0’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Meta-Sitosterol 2.0's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-sitosterol 7 references
- Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
- Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
- Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
- Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
- Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC