No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

MSM 1,000 mg Ingredients & Drug Interactions

by Country Life

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

MSM 1,000 mg is a dietary supplement by Country Life with 2 active ingredients. Its ingredients are commonly taken for acne and oily skin, rosacea, seborrheic dermatitis and dandruff.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of MSM 1,000 mg by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: MSM and sulfur. MSM is included at 1,000 mg per dose.

Sulfur is the supporting active ingredient. The tablet also contains several inactive ingredients — cellulose, stearic acid, a cellulose and glycerin coating, silica, magnesium stearate, and vegetable glaze — which are standard binders, fillers, and coating materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: source of sulfur, essential trace mineral.
  • We looked for evidence on: Acne, Dandruff, Rosacea, Scabies, Joint health, Connective tissue support.
  • The strongest evidence on file: Sulfur is rated "Possibly Effective" for Scabies (Natural Medicines).
  • Also on file: Sulfur is rated "Possibly Effective" for Dandruff.
  • Also on file: Sulfur is rated "Insufficient Reliable Evidence To Rate" for Acne, Rosacea.

Sulfur is possibly effective for scabies and dandruff based on available evidence. For acne, allergic rhinitis (hay fever), chronic obstructive pulmonary disease (COPD), and common cold, the evidence we hold is insufficient to rate whether it works.

We don't have effectiveness data on file for MSM in this product.

The evidence, ingredient by ingredient Sulfur

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topical sulfur is generally well tolerated, though it can cause skin dryness, irritation, and itching. Taken by mouth, sulfur is less studied; reported side effects include diarrhea and, in rare cases, metabolic acidosis (a change in blood pH).

One case report documented this serious effect in a woman who consumed a very large amount — about 250 grams over 6 days — and had underlying kidney and blood sugar problems. Because this product is an oral supplement, use it only with guidance from your healthcare provider.

For pregnancy and breastfeeding, sulfur is rated possibly safe, though data is limited and you should avoid applying it near the breast. We don't have pregnancy or breastfeeding safety information on file for MSM.

Side effects, ingredient by ingredient Sulfur

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Because we don't hold a monograph for MSM, there's a small information gap — but the sulfur component poses no known drug interaction risks.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is used for skin conditions like scabies and dandruff, where sulfur shows some promise. If you're considering it for acne, hay fever, or a respiratory condition, talk it over with your doctor first — the evidence doesn't yet support those uses.

Because this is an oral sulfur supplement and long-term safety data is thin, check with your own doctor or pharmacist before starting, especially if you have kidney disease, diabetes, or digestive issues.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MSM 1,000 mg, straight from the product label.

Brand Country Life
Barcode (UPC) 015794027706
Market status On market
Date entered into DSLD Mar 25, 2013
DSLD ID 14110
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MSM 1,000 mg by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
015794027706
IngredientAmount% DV
MSM1000 mg--
Sulfur340 mg--

Other ingredients: Cellulose, Stearic Acid, Cellulose & Glycerin Coating, Silica, Magnesium Stearate, Vegetable Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Do not accept if seal is broken.

Keep out of the reach of children.

WARNING: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reactions occur, stop taking the product and consult your doctor.

General

Product No. 2770 06F10L

Storage

Store between 59(0)-86(0) F.

General Statements

MSM is a source of sulfur, an essential trace mineral. Sulfur is essential for numerous structural functions in human metabolism.

SPECIALTY SUPPLEMENTS

Sulfur is essential for connective tissue, musculoskeletal, and skin health

Tablets

Formulation

NO: Yeast, corn, wheat, soy, gluten, milk, salt, sugar, starch, preservatives or artificial color.

Gluten-Free

Seals/Symbols

K PARVE

Certified Vegan AVA(TM) American Vegetarian Association Good Manufacturing Practices GMP CERTIFIED Certified GF(R) Gluten-Free PLEASE RECYCLE (recycle) Our manufacturing supports wind power renewablechoice.com

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) tablet daily with food or as directed by a health care professional. As a reminder, discuss the supplements and medications that you take with your health care providers.

See for yourself

MSM 1,000 mg by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in MSM 1,000 mg by Country Life

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

MSM

1000 mg per serving

Sulfur

No known
interactions
340 mg per serving Form: Methylsulfonylmethane

Sulfur is a mineral used mainly in topical skin products for acne, rosacea, dandruff, and certain skin infections, and has a long history in dermatolo...

Sulfur monograph & interactions

Other (inactive) ingredients: Cellulose, Stearic Acid, Cellulose & Glycerin Coating, Silica, Magnesium Stearate, Vegetable Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

MSM 1,000 mg by Country Life Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in MSM 1,000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for MSM 1,000 mg, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

MSM 1,000 mg by Country Life: Common Questions

Does MSM 1,000 mg by Country Life interact with any medications?
We do not currently list a known interaction for the mapped ingredients in MSM 1,000 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
MSM 1,000 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does sulfur do in this product?
Sulfur is possibly effective for scabies and dandruff. For other conditions like acne or hay fever, the evidence we have isn't strong enough to say whether it works.
Can I take this if I'm pregnant or breastfeeding?
Sulfur is rated possibly safe in pregnancy and lactation, though the data is limited. Talk with your doctor or pharmacist about whether it's right for you in these situations; if you're breastfeeding, avoid applying it near the breast.
What side effects might I experience?
The most common ones reported with oral sulfur are diarrhea and digestive irritation. Rarely, very high doses can cause metabolic acidosis. If you have kidney disease or diabetes, that risk may be higher — check with your doctor first.
Is this safe to use long-term?
Long-term safety data for oral sulfur supplements is limited. Use it only under guidance from your healthcare provider, especially if you plan to take it regularly.
What's in this tablet besides the active ingredients?
It contains cellulose, stearic acid, a cellulose and glycerin coating, silica, magnesium stearate, and vegetable glaze — all standard inactive ingredients that help hold and coat the tablet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MSM 1,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MSM 1,000 mg label
Go deeper

The Full Monographs Behind MSM 1,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

MSM 1,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulfur 17 references
  1. Blum, J. E. and Coe, F. L. Metabolic acidosis after sulfur ingestion. N Engl J Med 1977;297(16):869-70. PubMed
  2. Roos, T. C., Alam, M., Roos, S., Merk, H. F., and Bickers, D. R. Pharmacotherapy of ectoparasitic infections. Drugs 2001;61(8):1067-88. PubMed
  3. Diaz, M., Cazorla, D., and Acosta, M. [Efficacy, safety and acceptability of precipitated sulphur petrolatum for topical treatment of scabies at the city of Coro, Falcon State, Venezuela]. Rev Invest Clin 2004;56(5):615-22.
  4. Schmiedel, V. and Klein, P. A complex homeopathic preparation for the symptomatic treatment of upper respiratory infections associated with the common cold: An observational study. Explore (NY) 2006;2(2):109-14. PubMed
  5. Weiser, M., Gegenheimer, L. H., and Klein, P. A randomized equivalence trial comparing the efficacy and safety of Luffa comp.-Heel nasal spray with cromolyn sodium spray in the treatment of seasonal allergic rhinitis. Forsch Komplementarmed 1999;6(3):142- PubMed
  6. FDA OTC ingredients list, April 2010. Available at: www.fda.gov/downloads/AboutFDA/CentersOffices/CDER/UCM135691.pdf (accessed 2/7/15).
  7. Leyden, J. J., McGinley, K. J., Mills, O. H., Kyriakopoulos, A. A., and Kligman, A. M. Effects of sulfur and salicylic acid in a shampoo base in the treatment of dandruff: a double-blind study using corneocyte counts and clinical grading. Cutis 1987;39(6)
  8. Trumbore, M. W., Goldstein, J. A., and Gurge, R. M. Treatment of papulopustular rosacea with sodium sulfacetamide 10%/sulfur 5% emollient foam. J Drugs Dermatol 2009;8(3):299-304.
  9. Pelle, M. T., Crawford, G. H., and James, W. D. Rosacea: II. Therapy. J Am Acad Dermatol 2004;51:499-512.
  10. Blom I, Hornmark AM. Topical treatment with sulfur 10 per cent for rosacea. Acta Derm Venereol 1984;64:358-9. DOI
  11. Gupta, A. K. and Nicol, K. The use of sulfur in dermatology. J Drugs Dermatol 2004;3(4):427-31.
  12. Akhavan, A. and Bershad, S. Topical acne drugs: review of clinical properties, systemic exposure, and safety. Am J Clin Dermatol 2003;4(7):473-92.
  13. Wilkinson RD, Adam JE, Murray JJ, Craig GE. Benzoyl peroxide and sulfur: foundation for acne management. Can Med Assoc J 1966;95(1):28-9.
  14. Food and Drug Administration. Classification of benzoyl peroxide as safe and effective and revision of labeling to drug facts format; topical acne drug products for over-the-counter human use; final rule. Federal Register 2010;75(42):9767-77.
  15. Lin, A. N., Reimer, R. J., and Carter, D. M. Sulfur revisited. J Am Acad Dermatol 1988;18(3):553-8.
  16. Goszcz, A., Kostka-Trabka, E., Grodzinska, L., et al. [The effect of treatment with sulphur water from the spring in Wieslaw in Busko-Solec on levels of lipids, the fibrinolytic system and thrombogenic platelet function in patients with arteriosclerosis].
  17. Contoli M, Gnesini G, Forini G, et al. Reducing agents decrease the oxidative burst and improve clinical outcomes in COPD patients: a randomised controlled trial on the effects of sulphurous thermal water inhalation. ScientificWorldJournal. 2013 Dec 23;20 PubMed

See these in context on the Sulfur monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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