MSM Ingredients & Drug Interactions
What is this page for?
First and foremost: checking MSM against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
MSM is a dietary supplement by Higher Nature with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of MSM by Higher Nature
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about MSM, straight from the product label.
| Brand | Higher Nature |
|---|---|
| Barcode (UPC) | 5031013100017 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2024 |
| DSLD ID | 304543 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for MSM by Higher Nature, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Methylsulfonylmethane | 1000 mg | -- |
Other ingredients: Lithothamnium calcareum, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate, Hydroxypropyl Methylcellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
No artificial colours, flavours or preservatives. No yeast, added sugar or salt.
This product has not been tested on animals.
Advanced formula Optimal benefit
Vegetarian and Vegan
Precautions
Warning: If you are pregnant, breastfeeding, taking any medication or have a medical condition, please consult your healthcare professional before using this product.
Initially may cause laxative effect. This is normal, drink water and reduce intake if symptoms persist.
Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.
General Statements
Body Health
Formula
Dietary sulphur
Dietary sulphur, needed for collagen and keratin production MSM is a component of cartilage
FDA Statement of Identity
Food Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults take 1-6 tablets a day with meals building gradually.
Storage
Storage: Store in a cool, dry place out of reach of children.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
MSM by Higher Nature label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in MSM by Higher Nature
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Methylsulfonylmethane
Other (inactive) ingredients: Lithothamnium calcareum, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate, Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.
MSM by Higher Nature Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in MSM. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for MSM, from the product label.
Higher Nature
See all Higher Nature products- Name
- Higher Nature Ltd (EU)
- Street Address
- Block 1, Blanchardstown Corporate Park, Ballycoolen Road
- City
- Dublin
- ZipCode
- D15 AKK1
- Web Address
- highernature.com
MSM by Higher Nature: Common Questions
Does MSM by Higher Nature interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if MSM is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
MSM's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC