No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Nail-Ex Biotin 2.5 mg Ingredients & Drug Interactions

by Rising

Tablet Or Pill Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Nail-Ex Biotin 2.5 mg is a dietary supplement by Rising with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Nail-Ex Biotin 2.5 mg by Rising

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Nail-Ex Biotin 2.5 mg contains one active ingredient: biotin, a B vitamin. The tablets also contain inactive ingredients (fillers and binders) — di-calcium phosphate, microcrystalline cellulose, croscarmellose sodium, stearic acid, and magnesium stearate — that help hold the tablet together.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Support for excellent nails.
  • We looked for evidence on: Brittle nails, Nail health, Nail strength, Onychoschizia.
  • The closest evidence on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails (Natural Medicines).

Biotin is likely effective for biotin deficiency — a real but uncommon shortage of this B vitamin. For multiple sclerosis and seborrheic dermatitis (a scaly, itchy scalp or face condition), the evidence we have suggests biotin is possibly ineffective.

For alopecia areata (sudden hair loss in patches), we don't have reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body removes excess in your urine. High-dose biotin has rarely been linked to mild diarrhea — two patients taking 300 mg daily reported it.

One isolated case report described a rare inflammation of the heart and lung lining in someone taking 10 mg biotin daily along with other supplements and medications, but it's unclear whether biotin was the cause. Normal dietary amounts and amounts in prenatal vitamins are considered appropriate, but talk with your doctor before taking high-dose biotin supplements.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the biotin in this product. Run your exact medications through the interaction checker on this page to be sure, and mention this supplement to your doctor or pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is a straightforward biotin supplement useful if you have a confirmed biotin deficiency. If you're taking it for hair, skin, or nails without a known deficiency, the evidence for those uses isn't strong.

Check with your doctor or pharmacist before starting, especially if you're pregnant, nursing, or taking any other supplements or medications regularly.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Nail-Ex Biotin 2.5 mg, straight from the product label.

Brand Rising
Barcode (UPC) 364980126038
Net contents 30 Tablet(s)
Market status On market
Date entered into DSLD Nov 21, 2012
DSLD ID 15741
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Nail-Ex Biotin 2.5 mg by Rising, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
364980126038
IngredientAmount% DV
Biotin2500 mcg833%

Other ingredients: Di-Calcium Phosphate, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Discontinue immediately and consult your physician if you experience any side-effects.

Made in USA

For excellent nails.

*300 micrograms (mcg) is 100% of the US FDA Daily Value for biotin.

64980-126-03

Precautions

KEEP OUT OF REACH OF CHILDREN.

Do not use if blister packs have been opened.

Do not use if you have any known allergies or hypersensitivities to any of the ingredients.

Warnings: As with any drug or supplement, consult your physician before taking this product or if you are pregnant or nursing.

Consult a physician for use in children under 12.

Suggested/Recommended/Usage/Directions

Directions: Take one tablet daily with water as a nutritional supplement for adults, or as directed by a healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or illness.

Brand IP Statement(s)

*Appearex(R) is a registered trademark of Merz(R) Pharmaceuticals Inc. Nailex is not manufactured by, licensed from or approved by Merz(R) Pharmaceuticals Inc.. Rising does not claim bio-equivalence of Nail-ex(TM) to Appearex(R).

Compare to active ingredient in Appearex(R)*

For excellent nails.(TM)

Seals/Symbols

Rising

Storage

Storage: Keep tightly closed in a dry place at room temperature (59(0)F – 86(0)F).

Formula

Active Ingredient: Each tablet contains 2.5mg biotin as a nutritional supplement.

See for yourself

Nail-Ex Biotin 2.5 mg by Rising label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Nail-Ex Biotin 2.5 mg by Rising

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Biotin

No known
interactions
2500 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Di-Calcium Phosphate, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Nail-Ex Biotin 2.5 mg by Rising Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Nail-Ex Biotin 2.5 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Nail-Ex Biotin 2.5 mg, from the product label.

Rising

See all Rising products
Name
Rising Pharmaceuticals, Inc.
City
Paramus
State
NJ
ZipCode
07652
Pharmacist Counseling Corner

Nail-Ex Biotin 2.5 mg by Rising: Common Questions

Does Nail-Ex Biotin 2.5 mg by Rising interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Nail-Ex Biotin 2.5 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Nail-Ex Biotin 2.5 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe during pregnancy and breastfeeding?
Yes — biotin is rated likely safe during pregnancy and lactation. Amounts from food and prenatal vitamins are appropriate. If you're thinking about taking a high-dose biotin supplement, talk with your doctor first to confirm it's right for you.
Will biotin help my hair or nails grow?
The evidence we have doesn't support that biotin works for hair loss or nail health in people without a biotin deficiency. If you have a confirmed deficiency, correcting it is important — but for general use, the data is weak.
What's the difference between biotin and the other B vitamins?
Biotin (also called B7 or vitamin H) is one of the eight B vitamins. It plays a role in breaking down food into energy and in maintaining healthy skin, hair, and nails — though supplementing it beyond what you eat or get from a deficiency correction hasn't been proven to boost those things.
Can I take too much biotin?
Your body removes excess biotin in your urine, so it's hard to overdose. That said, high-dose biotin has rarely been linked to mild diarrhea, and one very rare case reported an unusual heart and lung inflammation. Stick to normal amounts unless your doctor recommends otherwise.
Do I need biotin if I eat a normal diet?
Probably not. Biotin is found in many foods — eggs, almonds, fish, sweet potatoes — and most people get enough from eating. Supplementing is mainly useful if you have a diagnosed deficiency or your doctor recommends it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Nail-Ex Biotin 2.5 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Nail-Ex Biotin 2.5 mg label
Go deeper

The Full Monographs Behind Nail-Ex Biotin 2.5 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Nail-Ex Biotin 2.5 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring