Interactions on record — worth a quick check against your medications. Based on 4 of 8 ingredients. Check your meds →
Dietary supplement

No3 Drive Ingredients & Drug Interactions

by PS ProSupps

No3 Drive label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking No3 Drive against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

No3 Drive is a dietary supplement by PS ProSupps with 8 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 1,143 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gynostemma pentaphyllum extract, Agmatine Sulfate, L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against No3 Drive by PS ProSupps

Ask about any prescription or over-the-counter medication and we check it for interactions with No3 Drive by PS ProSupps — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of No3 Drive by PS ProSupps

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 12 active ingredients.
  • “No3 Drive(TM) Vasolialation Matrix” is a proprietary blend — the label gives one combined amount (700 mg) without saying how much of each component you get.
  • “GPLC Matrix” is a proprietary blend — the label gives one combined amount (527 mg) without saying how much of each component you get.
  • “Enhanced Nutrient Absorbtion Matrix” is a proprietary blend — the label gives one combined amount (110 mg) without saying how much of each component you get.

No3 Drive contains 12 active ingredients focused on circulation and athletic performance. L-citrulline, resveratrol, Panax notoginseng, astragalus, agmatine sulfate, gynostemma pentaphyllum extract, and propionyl-L-carnitine (GlycoPro) are the ones we have complete data on; we also cannot check Pterostilbene, D-Pinitol, Rutaecarpine, and Piceid.

The product includes inactive fillers and binders like maltodextrin, silica, magnesium stearate, and hypromellose to form the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Exercise performance and blood flow support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Erectile dysfunction (ED), Intermittent claudication, Cardiovascular disease (CVD), Coronary heart disease (CHD) — and 4 related terms.
  • The strongest evidence on file: Propionyl-l-carnitine is rated "Possibly Effective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Propionyl-l-carnitine is rated "Possibly Effective" for Intermittent claudication.
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.

The evidence is mixed and often limited. L-citrulline is possibly effective for athletic performance but possibly ineffective for muscle-building (sarcopenia), with insufficient evidence for heart disease and diabetes.

Resveratrol is possibly effective for obesity and hay fever, but possibly ineffective for heart disease and high cholesterol. Panax notoginseng shows possibly effective evidence for angina and stroke prevention, but possibly ineffective for heart attack.

Gynostemma pentaphyllum is possibly effective for diabetes. Propionyl-L-carnitine is possibly effective for heart failure, angina, and cardiovascular disease.

For most of the other conditions these ingredients are marketed for — Alzheimer's, anxiety, asthma, cancer — the evidence is listed as insufficient to rate. No3 Drive may support athletic performance and circulation, but solid proof for most uses isn't yet in our data.

The evidence, ingredient by ingredient L-citrulline Agmatine Jiaogulan Propionyl-l-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated in the short term, but long-term safety isn't fully studied for any of them. Common side effects include gastrointestinal upset (nausea, diarrhea, stomach discomfort, heartburn), dry mouth, dizziness, insomnia, and rash.

L-citrulline and agmatine may cause diarrhea or nausea; resveratrol may trigger diarrhea and loose stools; Panax notoginseng can cause dry mouth, nausea, vomiting, insomnia, and nervousness; jiaogulan may cause dizziness and insomnia; propionyl-L-carnitine may cause a fishy odor in urine, breath, and sweat. Pregnancy: the safety data advises against L-citrulline, Panax notoginseng, astragalus, agmatine, and propionyl-L-carnitine during pregnancy.

Resveratrol is rated possibly unsafe, and jiaogulan is also cautioned against. Breastfeeding: safety data is insufficient or advises against it for L-citrulline, resveratrol, Panax notoginseng, astragalus, agmatine, and propionyl-L-carnitine.

Jiaogulan safety during breastfeeding is not established. Talk to your doctor or pharmacist before use if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient L-citrulline Agmatine Jiaogulan Propionyl-l-carnitine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 7 of the 7 matched ingredients can interact with medications — Jiaogulan, Resveratrol, Propionyl-l-carnitine, Panax Notoginseng, Astragalus, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,144 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking No3 Drive, double-check with your pharmacist if you take any blood thinners or anticoagulants (warfarin, aspirin, etc.) — multiple ingredients may increase bleeding risk (Moderate severity). Blood pressure medications are a Moderate concern with L-citrulline and agmatine.

Diabetes drugs interact with astragalus, agmatine, and jiaogulan (Moderate severity). Immunosuppressants, lithium, and thyroid hormone replacements also have documented interactions with ingredients here (Moderate severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

No3 Drive is designed to boost blood flow and athletic performance using a blend of vasodilation ingredients, with some possibly effective support for circulation and exercise. It's not for you if you take blood pressure meds, blood thinners (anticoagulants or antiplatelet drugs), diabetes medications, immunosuppressants, lithium, or thyroid hormone — check with your pharmacist first.

Anyone pregnant, breastfeeding, or considering this product should talk to their healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about No3 Drive, straight from the product label.

Brand PS ProSupps
Barcode (UPC) 700867215271
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2015
DSLD ID 43826
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for No3 Drive by PS ProSupps, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
700867215271
IngredientAmount% DV
L-Citrulline0 NP--
Resveratrol0 NP--
Pterostilbene0 NP--
Panax notoginseng0 NP--
Astragalus membranaceous0 NP--
GlycoCarn0 NP--
D-Pinitol0 NP--
Rutaecarpine0 NP--
Agmatine Sulfate0 NP--
Piceid0 NP--
No3 Drive(TM) Vasolialation Matrix700 mg--
Gynostemma pentaphyllum extract0 NP--
GPLC Matrix527 mg--
GlycoPro0 NP--
Enhanced Nutrient Absorbtion Matrix110 mg--
AstraGin Proprietary Blend0 NP--
PteroPro(TM)0 NP--

Other ingredients: Maltodextrin, Hypromellose, L-Carnitine Fumarate, Silica, Magnesium Stearate, Stearic Acid, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

RESULTS . . . PERIOD!+

>>> NITRIC OXIDE AMPLIFIER+ > CLINICALLY-SUPPORTED ENERGY AND RECOVERY AGENTS +

MADE IN USA

FOLLOW US ON INSTAGRAM, FACEBOOK & TWITTER.

Precautions

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS.

DO NOT USE IF PREGNANT OR NURSING.

KEEP OUT OF REACH OF CHILDREN.

DO NOT CONSUME THIS PRODUCT IF YOU HAVE A MEDICAL CONDITION AND/OR ARE TAKING ANY PRESCRIPTION MEDICATION.

DO NOT EXCEED RECOMMENDED SERVINGS. DO NOT USE THIS PRODUCT IF YOU ARE AT RISK OR ARE BEING TREATED FOR HIGH BLOOD PRESSURE, KIDNEY, THYROID OR PSYCHIATRIC DISEASE, ANXIETY, DEPRESSION, SEIZURE, ENLARGED PROSTATE OR STROKE. ALWAYS CONSULT A PHYSICIAN BEFORE BEGINNING ANY SUPPLEMENT OR TRAINING PROGRAM.

FDA Disclaimer Statement

+ THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

DIETARY SUPPLEMENT

Seals/Symbols

Ps(R)

AGMAPURE(R) Natural Agmatine sulfate

ActiGin & AstraGin(TM)

INFUSED WITH Pteropro(TM)

Brand IP Statement(s)

> GLYCOCARN(R) FOR SKIN-SPLITTING PUMPS +

***GlycoCarn(R) is a registered trademark of Sigma-Tau HealthScience and is manufactured exclusively worldwide under USA Production Patent #6703042 and EP1202956.

****AstraGin(TM) and ActiGin(TM) are trademarks of NuLiv Science.

Formulation

> STIMULANT FREE +

GLUTEN FREE

Suggested/Recommended/Usage/Directions

SUGGESTED USE: AS A DIETARY SUPPLEMENT, TAKE 3 CAPSULES 30-45 MINUTES PRIOR TO TRAINING. FOR BEST RESULTS STACK WITH MR HYDE(TM) OR DR JEKYLL(TM).

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

No3 Drive by PS ProSupps label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

No3 Drive label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in No3 Drive by PS ProSupps

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

No3 Drive(TM) Vasolialation Matrix

700 mg per serving

GPLC Matrix

527 mg per serving

Enhanced Nutrient Absorbtion Matrix

110 mg per serving
  • › AstraGin Proprietary Blend
  • › PteroPro(TM)

Other (inactive) ingredients: Maltodextrin, Hypromellose, L-Carnitine Fumarate, Silica, Magnesium Stearate, Stearic Acid, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

No3 Drive by PS ProSupps Drug Interactions

Want to check YOUR meds against No3 Drive?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,143Drugs
1,143 Moderate

Ingredients driving the most interactions

Gynostemma pentaphyllum extract 327
Agmatine Sulfate 258
L-Citrulline 178
GlycoPro 19

Individual Drug Interactions

The ingredients in No3 Drive interact with 1,143 drugs. Click any drug to see the details.

4 of the 8 ingredients in No3 Drive interact with drugs. Each result below shows which ingredient is responsible. Gynostemma pentaphyllum extract Agmatine Sulfate L-Citrulline GlycoPro

Each ingredient & the kinds of drugs it affects

For each ingredient in No3 Drive with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gynostemma pentaphyllum extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research suggests that jiaogulan has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, jiaogulan might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that jiaogulan can lower blood glucose levels.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Clinical and animal studies suggest that jiaogulan can stimulate the immune system.

Likelihood Possible Evidence D
Gynostemma pentaphyllum extract full monograph & interactions

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline full monograph & interactions

GlycoPro3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, propionyl-L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine, the parent compound of propionyl-L-carnitine, might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation when L-carnitine was taken with acenocoumarol. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product. It is unclear if such an interaction would also occur with propionyl-L-carnitine.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, acetyl-L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism. It is unclear if such an interaction would occur with propionyl-L-carnitine.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Theoretically, propionyl-L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine, the parent compound of propionyl-L-carnitine, might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with propionyl-L-carnitine and warfarin.

Likelihood Possible Evidence D
GlycoPro full monograph & interactions
The maker

Brand information

Manufacturer and brand details for No3 Drive, from the product label.

PS ProSupps

See all PS ProSupps products
Name
PROSUPPS USA, LLC.
Street Address
601 Century Pkwy. Ste. 300
City
Allen
State
TX
ZipCode
75013
Web Address
www.prosupps.com
Pharmacist Counseling Corner

No3 Drive by PS ProSupps: Common Questions

Does No3 Drive by PS ProSupps interact with any medications?
Yes. Based on its ingredients, No3 Drive has a known interaction with 1,143 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
No3 Drive contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any ingredients I should avoid if I'm on blood thinners?
Yes — several ingredients interact with blood thinners. Resveratrol, Panax notoginseng, jiaogulan, and propionyl-L-carnitine all may increase bleeding risk when combined with anticoagulants or antiplatelet drugs like warfarin or aspirin. Talk to your pharmacist before using this product if you take any blood thinner.
Will this help my athletic performance?
L-citrulline in this product is rated possibly effective for athletic performance, and propionyl-L-carnitine shows possibly effective evidence for cardiovascular health. However, most other ingredients lack solid evidence for performance benefit in the data we hold.
What are the most common side effects?
Gastrointestinal upset — nausea, diarrhea, heartburn, and stomach discomfort — is the most frequently reported. You might also experience dry mouth, dizziness, insomnia, or rash. A small number of people report a fishy odor in urine, breath, or sweat from the propionyl-L-carnitine.
Is this safe to take while pregnant or breastfeeding?
The safety data advises against this product during pregnancy and breastfeeding for most ingredients. If you're pregnant, planning to become pregnant, or nursing, talk to your doctor or pharmacist before using it.
If I take diabetes medication, can I use this product?
Not without checking first. Astragalus, agmatine, and jiaogulan all have interactions with diabetes drugs and may increase the risk of low blood sugar (hypoglycemia). Your pharmacist or doctor needs to review your specific medication before you start.
Does this product contain any fillers or other inactive ingredients?
Yes. The inactive ingredients include maltodextrin, silica, magnesium stearate, hypromellose (a capsule material), stearic acid, titanium dioxide, and L-carnitine fumarate. These are excipients used to bind and form the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

No3 Drive label
Go deeper

The Full Monographs Behind No3 Drive’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph → Herb & supplement monograph

Jiaogulan

Interacts with 327 drugs

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and animal studies are promising for some u...

Read the full Jiaogulan monograph → Herb & supplement monograph

Propionyl-l-carnitine

Interacts with 19 drugs

Propionyl-l-carnitine is a form of the amino acid derivative carnitine that the body uses to help turn fat into energy, and it is studied mostly for circulation problems like peripheral arte...

Read the full Propionyl-l-carnitine monograph →
Sources

Sources & How We Checked

No3 Drive's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 83 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-citrulline 8 references
  1. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  2. Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
  3. Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
  4. Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
  5. Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
  7. Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
  8. Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed

See these in context on the L-citrulline monograph →

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
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Panax Notoginseng 15 references
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Astragalus 13 references
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Agmatine 3 references
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Jiaogulan 8 references
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Propionyl-l-carnitine 12 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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