No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Olive Leaf 250 mg Ingredients & Drug Interactions

by Nature's Way

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Olive Leaf 250 mg is a dietary supplement by Nature's Way with 2 active ingredients. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Olive Leaf 250 mg by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Olive Leaf Extract” is listed as a grouped ingredient — the label gives one combined amount (250 mg) without saying how much of each component you get.

This product contains 2 active ingredients: Olive Leaf Extract (which breaks down into its component parts, including Oleuropein) and Olive. The extract is the working part — it's the concentrated form of compounds pulled from olive leaves.

The inactive ingredients are Hypromellose (a capsule material) and Magnesium Stearate (a binder).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Olive's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supports heart health.
  • We looked for evidence on: Metabolic syndrome, Hypertension, Hyperlipidemia, Cardiovascular disease.
  • The closest evidence on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome (Natural Medicines).

The evidence for Olive in this supplement isn't established yet. We hold data on six uses — osteoporosis, indigestion (dyspepsia), exercise-related respiratory infections, shingles (herpes zoster), flu, and osteoarthritis — and all of them show insufficient reliable evidence to rate.

That doesn't mean it doesn't work; it means the research so far isn't solid enough for us to make a claim either way.

The evidence, ingredient by ingredient Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive as a food — the oil, whole olives — is very safe with long everyday use. Olive leaf extract appears well tolerated in the studies we've seen.

The most common side effects reported orally are headache and stomach discomfort. One trial participant reported skin and acne after using olive leaf extract.

A small number of people may have seasonal respiratory allergy to olive tree pollen. Because this is a concentrated supplement and not food-form olive, the long-term safety picture isn't as well studied as for olive oil or olives you'd eat.

We don't hold pregnancy or breastfeeding safety data for this ingredient — talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or breastfeeding.

Side effects, ingredient by ingredient Olive

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you're interested in trying Olive Leaf for general wellness, the side-effect data suggests it's generally well tolerated, though the evidence for specific health claims isn't established yet. The lack of known drug interactions is a plus.

Because safety data on concentrated supplements is thinner than on food-form olive, run it by your pharmacist or doctor first if you're on other medications or have health concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Olive Leaf 250 mg, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674640005
Net contents 60 Vegan Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 328004
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Olive Leaf 250 mg by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
033674640005
IngredientAmount% DV
Olive Leaf Extract250 mg--
Oleuropein30 mg--
Olive180 mg--

Other ingredients: Hypromellose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports heart health Botanicals are sourced where they grow best

Bottled and tested in the USA

Vegan Gelatin free

Plant powered

Gluten free. No wheat, soy, dairy, gelatin, or artificial colors or flavors. Non GMO Project Verified nongmoproject.org

Vegan Gelatin free

Formula

Standardized to 12% oleuropein (30 mg) per serving

250 mg Olive Leaf Extract per serving

General Statements

Explore more products at naturesway.com Bottle made from 50% post-consumer recycled plastic

Brand IP Statement(s)

Copyright 2024 Nature's Way Brands, LLC

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Non GMO Project Verified nongmoproject.org

Vegan Gelatin free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendation: Adults take 1 capsule two times daily with food or water.

Precautions

Caution: If you are pregnant, nursing, have a kidney disorder, or are taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Storage

Keep tightly closed. Store at room temperatures. Avoid excessive heat and direct sunlight.

See for yourself

Olive Leaf 250 mg by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Olive Leaf 250 mg by Nature's Way

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Olive Leaf Extract

No known
interactions
250 mg per serving

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive Leaf Extract monograph & interactions
  • › Oleuropein

Olive

No known
interactions
180 mg per serving

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Olive Leaf 250 mg by Nature's Way Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Olive Leaf 250 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Olive Leaf 250 mg, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
naturesway.com
Pharmacist Counseling Corner

Olive Leaf 250 mg by Nature's Way: Common Questions

Does Olive Leaf 250 mg by Nature's Way interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Olive Leaf 250 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Olive Leaf 250 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Headache and stomach discomfort are the most common ones reported. One person in a trial reported skin and acne. It's well tolerated overall in the studies we've seen.
Does this actually work?
The evidence isn't solid enough for us to say yet. We have data on six possible uses — including osteoarthritis, osteoporosis, and flu — but all show insufficient reliable evidence. That means more research is needed.
Is it safe if I eat olives or use olive oil already?
Whole olives and olive oil as food are very safe. This product is a concentrated supplement, so it's a different animal — the long-term safety of concentrated supplements is less well studied than everyday food use.
Can I take this if I'm pregnant or breastfeeding?
We don't have safety data on file for Olive in pregnancy or breastfeeding. Talk with your doctor or pharmacist to figure out what's right for you personally.
What's the difference between the Olive Leaf Extract and Oleuropein in this product?
The Olive Leaf Extract is the main ingredient — it's a blend of compounds pulled from olive leaves. Oleuropein is one of those compounds inside the extract. We weren't able to check Oleuropein for interactions on its own.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Olive Leaf 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Olive Leaf 250 mg label
Go deeper

The Full Monographs Behind Olive Leaf 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Olive Leaf 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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