No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Olive Leaf 500 mg Ingredients & Drug Interactions

by Natural Factors HerbalFactors

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Olive Leaf 500 mg is a dietary supplement by Natural Factors HerbalFactors with 1 active ingredient. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Olive Leaf 500 mg by Natural Factors HerbalFactors

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: olive leaf extract at 500 mg per capsule. The extract comes from the leaves of the olive plant and is concentrated — different from olive oil or whole olives you'd eat as food.

The capsule also holds rice powder, gelatin, and magnesium stearate as inactive ingredients that help hold it together and keep it stable.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Olive's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports the body's natural defense system.
  • We looked for evidence on: Exercise-induced respiratory infections, Influenza, Immune function, Viral infection.
  • The closest evidence on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections (Natural Medicines).
  • Also on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Influenza.

The evidence we hold doesn't establish that olive leaf extract works for any of the conditions it's marketed for — osteoporosis, dyspepsia (indigestion), exercise-induced respiratory infections, shingles, influenza, or osteoarthritis. The data shows insufficient reliable evidence to rate its effectiveness for each of these.

That doesn't mean it doesn't work; it means the studies aren't there yet or aren't strong enough to say.

The evidence, ingredient by ingredient Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive leaf extract appears to be well tolerated overall. In trials and use, the most common side effects reported were headache and stomach discomfort.

One person reported skin breakouts after using it, and people with seasonal pollen allergies to olive tree pollen should be aware that may be a trigger. The caution here is that while olives and olive oil as food are very safe, concentrated supplements like this one are less studied, so the full safety picture isn't clear — talk with your doctor or pharmacist before you start, especially if you're pregnant, breastfeeding, or have health concerns.

Side effects, ingredient by ingredient Olive

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for this product's ingredients. That said, run your exact medications through the checker on this page before starting, and confirm with your doctor or pharmacist that it's okay to add.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you're interested in trying olive leaf extract and you don't take medications that might interact with it, this product is generally well tolerated. The catch is that we don't have solid evidence it works for the conditions it claims to address.

Check with your own doctor or pharmacist before you start — they know your full health picture and can tell you whether it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Olive Leaf 500 mg, straight from the product label.

Brand Natural Factors HerbalFactors
Barcode (UPC) 068958045696
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2017
DSLD ID 76365
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Olive Leaf 500 mg by Natural Factors HerbalFactors, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
068958045696
IngredientAmount% DV
Olive leaf extract500 mg--

Other ingredients: Rice powder, Gelatin capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

isura Non-GMO - Mass Spec Documentation - Lab tested

Purity & potency guaranteed

Suggested/Recommended/Usage/Directions

Suggested Usage: 1 capsule 1-4 times per day between meals or as directed by a health professional. For maintenance, take 1 capsule 2 times per day.

Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Formula

Natural Factors Olive Leaf Extract is standardized to contain oleuropein, the powerful phytochemical responsible for supporting the body’s natural defense system.

15% Oleuropein

General Statements

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Product of Canada Recyclable container and label.

Support for the body's defense system

Formulation

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Storage

For freshness, store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General

R4

See for yourself

Olive Leaf 500 mg by Natural Factors HerbalFactors label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Olive Leaf 500 mg by Natural Factors HerbalFactors

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Olive leaf extract

No known
interactions
500 mg per serving Form: Oleuropein

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive leaf extract monograph & interactions

Other (inactive) ingredients: Rice powder, Gelatin capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Olive Leaf 500 mg by Natural Factors HerbalFactors Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Olive Leaf 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Olive Leaf 500 mg, from the product label.

Natural Factors HerbalFactors

See all Natural Factors HerbalFactors products
Name
Natural Factors Canada
Pharmacist Counseling Corner

Olive Leaf 500 mg by Natural Factors HerbalFactors: Common Questions

Does Olive Leaf 500 mg by Natural Factors HerbalFactors interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Olive Leaf 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Olive Leaf 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is olive leaf extract?
It's a concentrated extract made from the leaves of the olive plant — not the fruit you eat or the oil you cook with. Because it's concentrated, it's different from eating olives or olive oil as food, and it's less studied for safety.
Does olive leaf extract actually work?
The evidence we have doesn't establish that it works for osteoporosis, indigestion, respiratory infections, shingles, flu, or osteoarthritis. There just isn't enough reliable research yet to say either way.
What side effects might I get?
Most people tolerate it well. Headache and stomach discomfort are the most commonly reported. One person reported skin breakouts in a trial. If you have seasonal allergies to olive tree pollen, that could also be a concern.
Is it safe to take if I'm pregnant or breastfeeding?
There isn't enough data on file to know either way. Talk with your doctor or pharmacist — they can help you decide based on your individual situation.
Why the caution about concentrated supplements if olives and olive oil are safe?
Olives and olive oil as food are very well studied and safe. Concentrated supplements are different — they're less studied, so we know less about how safe they really are at higher doses over time.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Olive Leaf 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Olive Leaf 500 mg label
Go deeper

The Full Monographs Behind Olive Leaf 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Olive Leaf 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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