No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Olive Leaf Extract 300 mg Ingredients & Drug Interactions

by Pure Vegan

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Olive Leaf Extract 300 mg is a dietary supplement by Pure Vegan with 2 active ingredients. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Olive Leaf Extract 300 mg by Pure Vegan

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains 2 active ingredients: olive leaf standardized extract and DigeSEB Plus. The olive leaf provides a concentrated version of compounds found in olives and olive oil, though in a form that's less well-studied than eating the food itself.

The product also contains vegetable magnesium stearate and vegetable capsules as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Olive's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune system support.
  • We looked for evidence on: Exercise-induced respiratory infections, Influenza, common cold, viral infection.
  • The closest evidence on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections (Natural Medicines).
  • Also on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Influenza.

The evidence for olive leaf extract isn't established yet in the data we hold. Studies haven't reliably shown it works for osteoporosis, indigestion (dyspepsia), exercise-related respiratory infections, shingles, flu, or osteoarthritis — the ratings across all these are insufficient.

We don't have effectiveness information on file for DigeSEB Plus.

The evidence, ingredient by ingredient Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive leaf extract is generally well tolerated. The most common side effects reported in trials were headache and stomach discomfort; one person reported skin problems and acne.

Olive tree pollen can trigger seasonal respiratory allergies if you're sensitive. The caution here is that olives and olive oil as food are very safe, but concentrated supplements like this one are less studied, so check with your doctor before starting if you have any health concerns.

Side effects, ingredient by ingredient Olive

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the olive leaf standardized extract in our data. We couldn't verify interaction data for DigeSEB Plus, so check with your pharmacist if you want specifics on that ingredient before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This product has no documented interactions with medications for the ingredient we could verify, but we couldn't check one of the two actives. The evidence for how well it works isn't established in our data.

If you're curious about it, talk it over with your doctor or pharmacist — they know your health picture and can tell you whether it's a fit for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 10, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Olive Leaf Extract 300 mg, straight from the product label.

Brand Pure Vegan
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 10, 2014
DSLD ID 37157
Product type Botanical
Supplement form Capsule
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Olive Leaf Extract 300 mg by Pure Vegan, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
DigeSEB Plus25 mg--
Olive leaf standardized extract300 mg--

Other ingredients: Vegetable Magnesium Stearate, Vegetable Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE As a dietary supplement, take 1 capsule daily or as directed by a health professional.

General Statements

Olive Leaf is a powerful herbal anti-oxidant. Recorded evidence of olive leaf's medicinal use dates back thousands of years. Today, olive leaf is commonly used to help support the immune system.

Brand IP Statement(s)

Digeseb(R)Plus is a proprietary blend of acid stable plant based enzymes supplying (Amylase, Protease I, Protease II, Lipase and Cellulase) for enhanced bioavailability. Digeseb(R)Plus is a registered trademark of Specialty Enzymes & Biochemicals.

Precautions

Keep Out Of Reach Of Children

Storage

Store In A Cool Dry Place

Formula

Standardized 18% Oleuropein with Digeseb(R) Plus Delivery System

FDA Statement of Identity

A Dietary Supplement

Formulation

Does not contain any dairy, egg, sugar, corn, yeast, wheat, soy, glutens, artificial colors, flavors or preservatives.

See for yourself

Olive Leaf Extract 300 mg by Pure Vegan label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Olive Leaf Extract 300 mg by Pure Vegan

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

DigeSEB Plus

25 mg per serving

Olive leaf standardized extract

No known
interactions
300 mg per serving Form: Oleuropein

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive leaf standardized extract monograph & interactions

Other (inactive) ingredients: Vegetable Magnesium Stearate, Vegetable Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Olive Leaf Extract 300 mg by Pure Vegan Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Olive Leaf Extract 300 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Olive Leaf Extract 300 mg, from the product label.

Pure Vegan

See all Pure Vegan products
Name
Pure Vegan
City
Phoenix
State
AZ
ZipCode
85040
Phone Number
1-800-798-0707
Pharmacist Counseling Corner

Olive Leaf Extract 300 mg by Pure Vegan: Common Questions

Does Olive Leaf Extract 300 mg by Pure Vegan interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Olive Leaf Extract 300 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Olive Leaf Extract 300 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is olive leaf extract safe to take long-term?
Olive leaf extract is generally well tolerated in studies. The catch is that concentrated supplements are less studied than eating olives or olive oil as food, so the long-term safety picture isn't complete. Check with your doctor before taking it regularly, especially if you have other health conditions.
What side effects should I watch for?
Headache and stomach discomfort are the most common ones reported in trials. One person had skin and acne issues. If you're allergic to olive tree pollen, this product might trigger respiratory symptoms. Stop and talk to your pharmacist if anything feels off.
Does olive leaf extract actually help with arthritis or bone health?
The evidence isn't reliable enough yet to say it works for osteoarthritis or osteoporosis. Same goes for colds, shingles, and indigestion — the data we have rates all of these as insufficient. More research is needed.
Is it safe to take during pregnancy or breastfeeding?
We don't have safety data on file for either olive leaf extract or DigeSEB Plus in pregnancy or lactation. Talk with your doctor or pharmacist for personalized advice before taking this if you're pregnant or nursing.
What's the difference between olive leaf extract and olive oil?
Olive oil and whole olives as food are very safe and well studied. This product is a concentrated extract, which means the compounds are pulled out and concentrated in a way that's less well understood. That's why the caution here is stronger for the supplement form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Olive Leaf Extract 300 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Olive Leaf Extract 300 mg label
Go deeper

The Full Monographs Behind Olive Leaf Extract 300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Olive Leaf Extract 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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