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Eleuthero (Eleutherococcus senticosus) is a plant native to Asia and a member of the Araliaceae family. It is also commonly known as 'Siberian ginseng' or 'eleuthero root'. The root of the plant is used in traditional medicine for its purported ability to improve physical and mental performance, boost the immune system, and reduce fatigue. It is also claimed to have anti-inflammatory and antioxidant properties. Eleuthero is often referred to as an 'adaptogen'. Adaptogens are believed to help the body resist stress. It is important to note that although eleuthero is known as 'Siberian ginseng', it is not related to Panax ginseng.

Gotu kola (Centella asiatica) is a perennial herb and a member of the carrot family. It has small, white or pink flowers, fan-shaped leaves and is often found growing in damp, marshy areas. The leaves and stems of the gotu kola plant are used in herbal medicine as a natural remedy for a variety of health conditions, such as gastrointestinal disorders, amenorrhea, eye conditions, heat stroke, leprosy, liver health, lymphatic obstruction, and infections. It is not to be confused with similarly named plant, Cola Nut, or bacopa.

Guarana (Paullinia cupana) is a plant native to the Amazon rainforest in South America. The seeds of the guarana plant are used in traditional medicine and as a dietary supplement. Guarana is often marketed as a natural stimulant and is claimed to improve physical performance, increase energy and alertness, and reduce fatigue. It is sometimes added to energy drinks, weight loss supplements, and other products. Guarana seeds typically contain around 3-6% caffeine, although some extracts may contain far more. Guarana, when used in dietary supplements, is often standardized for its caffeine and tannin content.