Optimized Resveratrol 250 mg With Synergistic Grape-Berry Actives By Life Extension Overview & Drug Interactions
Check For Interactions With Optimized Resveratrol 250 mg With Synergistic Grape-Berry Actives
Supplement: Optimized Resveratrol 250 mg With Synergistic Grape-Berry Actives by Life Extension
Optimized Resveratrol 250 mg With Synergistic Grape-Berry Actives Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
Trans-Resveratrol
Resveratrol is a natural compound found in certain plants, including grapes, berries, and peanuts. It has been the subject of numerous scientific studies due to its potential health benefits. Some research suggests that resveratrol may have antioxidant, anti-inflammatory, and cardioprotective effects. It may also have potential as a cancer-fighting agent and may help to improve glucose metabolism and insulin sensitivity.
See More Information Regarding Resveratrol| Ingredient Group | Resveratrol |
|---|---|
| Category | non-nutrient/non-botanical |
- Glycosides
- Japanese Knotweed
- Red Grape extracts
Blend
| Ingredient Group | Blend (Herb/Botanical) |
|---|---|
| Category | blend |
-
Red Grape
Description:Grapes are widely grown and cultivated for a variety of uses such as for food and beverage making (e.g., wine). They also have a long history of use in traditional medicine. The fruit and skin of grapes contain various compounds that are believed to have health benefits, including antioxidants such as resveratrol and flavonoids. These compounds may help to protect cells from damage and are purported to reduce the risk of certain chronic diseases. Grapes and grape products may also have anti-inflammatory properties, which may help to reduce inflammation in the body and potentially improve symptoms of certain conditions. Grape seed extracts are also commonly used as a dietary supplement and are often standardized according to the content of polyphenols or proanthocyanidins.
See More Information Regarding Grape
Ingredient Group Grape Category botanical
Wild Blueberry
Ingredient Group Blueberry Category botanical
Japanese Knotweed Extract Blend (Non-Nutrient/Non-Botanical)
Ingredient Group Hu Zhang Category botanical
-
Polyphenols
Ingredient Group Polyphenol (unspecified) Category non-nutrient/non-botanical
Anthocyanins
Ingredient Group Anthocyanidins (unspecified) Category non-nutrient/non-botanical
OPCs
Ingredient Group Proanthocyanidins (unspecified) Category non-nutrient/non-botanical
Free Resveratrol
Description:Resveratrol is a natural compound found in certain plants, including grapes, berries, and peanuts. It has been the subject of numerous scientific studies due to its potential health benefits. Some research suggests that resveratrol may have antioxidant, anti-inflammatory, and cardioprotective effects. It may also have potential as a cancer-fighting agent and may help to improve glucose metabolism and insulin sensitivity.
See More Information Regarding Resveratrol
Ingredient Group Resveratrol Category non-nutrient/non-botanical
Resveratrol conjugates
Description:Resveratrol is a natural compound found in certain plants, including grapes, berries, and peanuts. It has been the subject of numerous scientific studies due to its potential health benefits. Some research suggests that resveratrol may have antioxidant, anti-inflammatory, and cardioprotective effects. It may also have potential as a cancer-fighting agent and may help to improve glucose metabolism and insulin sensitivity.
See More Information Regarding Resveratrol
Ingredient Group Resveratrol conjugates (mixed) Category non-nutrient/non-botanical
-
Epsilon-Viniferin
Ingredient Group Viniferin Category non-nutrient/non-botanical
Trans Polydatin
Ingredient Group Polydatin Category non-nutrient/non-botanical
Cis-Polydatin
Ingredient Group Polydatin Category non-nutrient/non-botanical
Resveratrol analogs
Description:Resveratrol is a natural compound found in certain plants, including grapes, berries, and peanuts. It has been the subject of numerous scientific studies due to its potential health benefits. Some research suggests that resveratrol may have antioxidant, anti-inflammatory, and cardioprotective effects. It may also have potential as a cancer-fighting agent and may help to improve glucose metabolism and insulin sensitivity.
See More Information Regarding Resveratrol
Ingredient Group Resveratrol analog (unspecified) Category non-nutrient/non-botanical Forms- Pterostilbene
Quercetin
Quercetin is a type of flavonoid, which is a class of compounds found in a wide variety of plants and foods. It is purported to have a number of health benefits such as anti-inflammatory, antioxidant, and immune-boosting effects. Studies suggest it may also help to reduce the risk of certain chronic diseases, such as heart disease. In addition, quercetin may have anti-allergic properties and may be helpful in the treatment of allergies and asthma. It is a popular dietary supplement worldwide and is often included in products that contain antioxidants or various vitamins/minerals. Its wide range of potential health benefits mean that it could potentiate the effects of other drugs (e.g., anti-hypertensives), which is why there are an abundant number of potential interactions listed for quercetin.
See More Information Regarding Quercetin| Ingredient Group | Quercetin |
|---|---|
| Category | non-nutrient/non-botanical |
- Quercetin Dihydrate
Trans-Pterostilbene
| Ingredient Group | Pterostilbene |
|---|---|
| Category | non-nutrient/non-botanical |
- pTeroPure
Fisetin
| Ingredient Group | Fisetin |
|---|---|
| Category | non-nutrient/non-botanical |
- Rhus succedanea L.
Drugs that interact with Optimized Resveratrol 250 mg With Synergistic Grape-Berry Actives by Life Extension
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Vegetarian Capsule(s)
|
| Maximum serving Sizes: |
1 Vegetarian Capsule(s)
|
| Servings per container | 60 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| Trans-Resveratrol |
250 mg
|
Resveratrol |
|
| Blend |
85 mg
|
Blend (Herb/Botanical) |
|
| Red Grape |
0 NP
|
Grape |
|
| Wild Blueberry |
0 NP
|
Blueberry |
|
| Japanese Knotweed Extract Blend (Non-Nutrient/Non-Botanical) |
0 NP
|
Hu Zhang |
|
| Polyphenols |
0 NP
|
Polyphenol (unspecified) |
|
| Anthocyanins |
0 NP
|
Anthocyanidins (unspecified) |
|
| OPCs |
0 NP
|
Proanthocyanidins (unspecified) |
|
| Free Resveratrol |
0 NP
|
Resveratrol |
|
| Resveratrol conjugates |
0 NP
|
Resveratrol conjugates (mixed) |
|
| Epsilon-Viniferin |
0 NP
|
Viniferin |
|
| Trans Polydatin |
0 NP
|
Polydatin |
|
| Cis-Polydatin |
0 NP
|
Polydatin |
|
| Resveratrol analogs |
0 NP
|
Resveratrol analog (unspecified) |
|
| Quercetin |
60 mg
|
Quercetin |
|
| Trans-Pterostilbene |
0.5 mg
|
Pterostilbene |
|
| Fisetin |
10 mg
|
Fisetin |
|
| Other Ingredients: |
Vegetable Cellulose
Microcrystalline Cellulose
Silica
Vegetable Stearate
Maltodextrin
Forms
|
|---|
Label Statments:
| General Statements |
- Pterostilbene, a stilbene compound from the same family as resveratrol, has been shown to work synergistically with resveratrol, to unlock one's longevity genes...thus conferring even greater anti-aging benefits. In laboratory tests, pterostilbene has shown promise for supporting cardiovascular health, glucose levels that are already within normal range, anti-aging and cognitive function.178-185 It helps improve mitochondrial function and supports healthy metabolic function by activating SIRT1 and mimicking calorie restriction.186, 187 It has also shown potential to ease inflammation and support antioxidant activity.181, 185
- Fisetin, found in strawberries, has the power to "switch on" cell signaling molecules that support youthful gene expression, DNA protection, and healthy cellular function.160 Fisetin also supports aging neurons in the presence of oxidative stress.161-165 And, most importantly, it works in synergy with resveratrol. Researchers have uncovered compelling evidence of fisetin's ability to stabilize resveratrol by shielding it from metabolic breakdown, 166 thus extending its beneficial effects! So naturally we added it, along with these four calorie restriction mimics, to this most advanced resveratrol formulation.
- The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging.
- Life Extension has identified certain compounds that mimic calorie restriction's ability to trigger youthful gene expression, the process by which genes transmit signals that slow certain aspects of aging.
- Findings from published scientific literature indicate that resveratrol may be the most effective compound for maintaining optimal health and promoting longevity,144 Resveratrol is a phytoalexin, a polyphenolic compound which is produced by Vitis vinifera as a response to attack by molds. Because of the widespread use of pesticides in modern wine making, including the practice of copper sulfation, the level of resveratrol in modern wines has plummeted. Red wine contains resveratrol, but the quantity varies depending on where the grapes are grown, the time of harvest and other factors. In fact, usually only one to three mg of resveratrol per liter of red wine is currently found, even in the most robust red wines. After years of relentless research, a standardized resveratrol extract is now available as a dietary supplement.
- Research funded by the Life Extenstion Foundation showed that a combination of low-dose (20 mg) resveratrol plus grapeseed extract mimicked many of the favorable gene expression changes seen in calorie-restricted animals. Other studies, however, indicate that higher doses may be needed to obtain all of resvertrol's positive benefits including promoting healthy insulin sensitivity, enhanced mitochondrial function, reduced expression of inflammatory factors, and protection against the effects of a high-fat diet.145-159
- Life Extension has evaluated published studies on resveratrol to establish the doses humans might need to take a duplicate the remarkable laboratory findings. The results of Life Extension's analysis yield a wide range of potentially effective doses: from 20 to 250 mg a day and higher. The resveratrol potency you choose may be based on your current state of health and/or your desire to reach the upper limits of a healthy human life span.
|
|---|---|
| Brand IP Statement(s) |
- pTeroPure(R) is a registered trademark of ChromaDex, Inc.
- All contents Copyright (C) 1995-2013 Life Extension(R) All rights reserved
- Foundation for Longer Life
|
| Suggested/Recommended/Usage/Directions |
- Dosage and Use
~ Take one capsule daily with or without food, or as recommended by a healthcare practitioner.
|
| Precautions |
- Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
- Warnings
~ Keep out of reach of children
- ~ Do not exceed recommended dose
~ Do not purchase if outer seal is broken or damaged.
- ~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating
- You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health program. You should not stop taking any medication without first consulting your physician.
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| Formula |
- These compounds include trans-resveratrol (which researchers contend is the most active constituent), whole grape extract, quercetin, plus certain compounds found in berries, including trans-pterostilbene and now fisetin.
|
Brand Information
See all products by this brand
| To report a serious adverse event or obtain product information, contact | |
|---|---|
| Phone Number | 1-866-280-2852 |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.