No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Pancreatin & Lipase 500 mg Ingredients & Drug Interactions

by Dr. Clark Store

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Pancreatin & Lipase 500 mg is a dietary supplement by Dr. Clark Store with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pancreatin & Lipase 500 mg by Dr. Clark Store

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Pancreatin” is listed as a grouped ingredient — the label gives one combined amount (400 mg) without saying how much of each component you get.

This product contains 3 active ingredients: Amylase, Protease, and Lipase — all digestive enzymes that help break down food. Protease breaks down protein, Lipase handles fat, and Amylase breaks down carbohydrates.

The capsules themselves are made from gelatin.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This product is marketed for general wellness, not a specific health condition, so there's no single claim to grade against clinical evidence.

Why this rating?
  • The label markets general wellness (“supports healthy digestion”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for these enzymes is limited. For Lipase, we don't have enough reliable data to rate it for inflammatory bowel disease, general indigestion, or prematurity.

Amylase and Protease effectiveness ratings aren't on file in our data.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and Lipase are generally well tolerated in adults, though digestive upset or allergic reactions can occasionally occur. Protease is best avoided in pregnancy unless your doctor prescribes it.

During breastfeeding, there's little safety data for either ingredient — talk with your healthcare provider first. Lipase carries a serious caution: premature infants given a recombinant form (rhBSSL) have experienced severe gastrointestinal problems and a slightly elevated risk of a serious bowel condition called necrotizing enterocolitis (a damaged intestinal lining).

Adults with serious digestive conditions should use this product only under medical guidance.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure marketed for general wellness rather than one specific gradeable purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have normal digestion and no pregnancy or breastfeeding concerns, these enzymes are generally tolerated. Anyone with serious digestive disease, or anyone pregnant or nursing, should talk with their doctor or pharmacist first.

Check your exact medications with our tool below — no interactions are documented for the ingredients we could verify.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pancreatin & Lipase 500 mg, straight from the product label.

Brand Dr. Clark Store
Barcode (UPC) 652384106832
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220331
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pancreatin & Lipase 500 mg by Dr. Clark Store, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
652384106832
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Pancreatin400 mg--

Other ingredients: Gelatin Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule with each meal, or as directed by a healthcare professional.

Formulation

Our products don't contain flow agents like magnesium stearate. Not now, not ever.

Supports healthy digestion

Seals/Symbols

Made in USA

GMP Quality Assured

General Statements

Leader in purity Established by Dr. Clark's family in 1993

Company does not adopt any Dr. Clark claims.

FDA Statement of Identity

Dietary Supplement

Storage

After opening, keep tightly closed in a cool place.

Precautions

Keep away from children.

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Pancreatin & Lipase 500 mg by Dr. Clark Store label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pancreatin & Lipase 500 mg by Dr. Clark Store

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pancreatin

400 mg per serving

Other (inactive) ingredients: Gelatin Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pancreatin & Lipase 500 mg by Dr. Clark Store Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pancreatin & Lipase 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pancreatin & Lipase 500 mg, from the product label.

Dr. Clark Store

See all Dr. Clark Store products
Name
Self Health Resource Center
Street Address
1055 Bay Blvd., Ste A
City
Chula Vista
State
CA
ZipCode
91911
Phone Number
866-372-5275
Web Address
www.DrClarkStore.com
Pharmacist Counseling Corner

Pancreatin & Lipase 500 mg by Dr. Clark Store: Common Questions

Does Pancreatin & Lipase 500 mg by Dr. Clark Store interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pancreatin & Lipase 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pancreatin & Lipase 500 mg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy?
Protease is best avoided unless your doctor prescribes it. Lipase hasn't been well studied in pregnancy, so use it only if your doctor advises you to. Talk with your healthcare provider about whether this product is right for you.
Can I use this while breastfeeding?
There's little safety data for either Protease or Lipase during breastfeeding. Check with your healthcare provider first before using this product.
What are these enzymes supposed to do?
They're digestive enzymes designed to help break down food — Protease handles protein, Lipase handles fat, and Amylase handles carbohydrates.
Are there any side effects?
Most adults tolerate these enzymes well. Occasionally, digestive upset can happen. Protease rarely causes allergic reactions. If you have a serious digestive condition, use this only under medical guidance.
Does the evidence show it actually works?
We don't have enough reliable data to rate these enzymes for conditions like indigestion or inflammatory bowel disease. The evidence isn't established in our records.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pancreatin & Lipase 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pancreatin & Lipase 500 mg label
Sources

Sources & How We Checked

Pancreatin & Lipase 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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