No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Pancreatin & Ox Bile Extract Ingredients & Drug Interactions

by Vital Nutrients

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Pancreatin & Ox Bile Extract is a dietary supplement by Vital Nutrients with 4 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pancreatin & Ox Bile Extract by Vital Nutrients

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Pancreatic Enzyme Blend” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains 4 active ingredients: protease and lipase (digestive enzymes that help break down protein and fat), amylase (a starch-digesting enzyme), and bile extract (which aids fat digestion and absorption). These work together as a pancreatic enzyme replacement, meant to support your digestive system when your own pancreas isn't producing enough enzymes.

The capsule also contains gelatin, calcium carbonate, and leucine as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive enzyme support.
  • We looked for evidence on: Dyspepsia, pancreatic insufficiency, fat malabsorption, digestive enzyme deficiency.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these digestive enzymes is mixed and limited. For inflammatory bowel disease and indigestion (dyspepsia), the research we hold rates the evidence as insufficient to know whether they help.

We don't have effectiveness ratings on file for amylase or bile extract, so we can't say how well this particular blend works for its intended purpose.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated in most adults, though digestive upset or allergic reactions can happen. Occupational exposure to airborne protease (like in certain work settings) has rarely triggered allergic rhinitis or asthma, and protease-specific IgE reactions have been reported.

Neither ingredient should be used in pregnancy unless prescribed by your doctor, and both require medical guidance before breastfeeding. If you have a serious digestive condition, check with your doctor before starting this product.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the digestive enzymes we could check in this product. That said, we have no interaction data for amylase or bile extract, so search your medications on this page to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This product is for people looking to supplement their digestive enzyme production, especially those with pancreatic insufficiency or malabsorption. If you're pregnant, breastfeeding, or have a serious digestive disorder, talk with your doctor or pharmacist first.

No interactions with medications are documented for the ingredients we checked, but verify your exact drugs before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pancreatin & Ox Bile Extract, straight from the product label.

Brand Vital Nutrients
Barcode (UPC) 693465436110
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 305135
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pancreatin & Ox Bile Extract by Vital Nutrients, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
693465436110
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Pancreatic Enzyme Blend500 mg--
Bile Extract200 mg--

Other ingredients: Gelatin, Calcium Carbonate, Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store sealed in a cool dry place

Precautions

Keep out of reach of children

Use only if safety seal is intact

Warning: if pregnant, consult your physician before taking.

Suggested/Recommended/Usage/Directions

Recommendations: 1 or 2 capsules at the start of each meal, or directed by your healthcare professional.

Formulation

Excludes coatings, binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, sugar. Verified by independent testing

Raw materials and finished products are independently tested by U.S. labs.

General Statements

Learn more at vitalnutrients.net

FDA Statement of Identity

Dietary Supplement

See for yourself

Pancreatin & Ox Bile Extract by Vital Nutrients label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pancreatin & Ox Bile Extract by Vital Nutrients

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pancreatic Enzyme Blend

500 mg per serving

Bile Extract

200 mg per serving Form: Bovine

Other (inactive) ingredients: Gelatin, Calcium Carbonate, Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pancreatin & Ox Bile Extract by Vital Nutrients Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pancreatin & Ox Bile Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pancreatin & Ox Bile Extract, from the product label.

Vital Nutrients

See all Vital Nutrients products
Name
Vital Nutrients
Street Address
45 Kenneth Dooley Drive
City
Middleton
State
CT
ZipCode
06457
Web Address
vitalnutrients.net
Pharmacist Counseling Corner

Pancreatin & Ox Bile Extract by Vital Nutrients: Common Questions

Does Pancreatin & Ox Bile Extract by Vital Nutrients interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pancreatin & Ox Bile Extract. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pancreatin & Ox Bile Extract contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Safety data for these enzymes in pregnancy is limited. Protease and lipase should be avoided in pregnancy unless your doctor prescribes them. Talk with your doctor or pharmacist before using this product if you're pregnant or planning to be.
Is it safe while breastfeeding?
There isn't enough safety data on protease or lipase during breastfeeding to recommend use without medical advice. Check with your healthcare provider first.
Can protease cause allergies?
Protease is generally well tolerated, but allergic reactions are possible. Rarely, occupational exposure to airborne protease has triggered allergic rhinitis or asthma, and protease-specific antibody reactions have been documented. If you work around enzymes or have a history of enzyme sensitivities, let your pharmacist know.
What is bile extract for?
Bile extract helps your body digest and absorb fats. It works alongside the enzymes in this blend as part of the pancreatic enzyme replacement system.
Does this work for inflammatory bowel disease or indigestion?
The research we have on these enzymes for inflammatory bowel disease and indigestion is not strong enough to say whether they help. Talk with your doctor about whether this is right for your specific condition.
Are there any side effects?
Digestive upset and allergic reactions are possible but not common in adults. No serious side effects have been reported, though a full safety study hasn't been completed. If you have a serious digestive condition, get medical guidance before using this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pancreatin & Ox Bile Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pancreatin & Ox Bile Extract label
Sources

Sources & How We Checked

Pancreatin & Ox Bile Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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