No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pantothenic Acid 1000 mg Ingredients & Drug Interactions

by NaturesPlus

Tablet Or Pill Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Pantothenic Acid 1000 mg is a dietary supplement by NaturesPlus with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pantothenic Acid 1000 mg by NaturesPlus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pantothenic acid (also called vitamin B5) at 1000 mg per tablet. Pantothenic acid is a B vitamin your body needs to convert food into energy and to make certain hormones and cholesterol.

The tablet also contains several inactive ingredients — stearic acid, microcrystalline cellulose, hydroxypropyl methylcellulose, rice bran, silica, magnesium stearate, and pharmaceutical glaze — which help hold the tablet together and allow it to dissolve properly.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Pantothenic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: stress support and adrenal gland function.
  • We looked for evidence on: Anxiety, Adrenal insufficiency, Cortisol support, Stress response.
  • The closest evidence on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).

Pantothenic acid is effective for treating pantothenic acid deficiency, which is rare in people eating a normal diet. For radiation dermatitis (skin damage from cancer treatment), the evidence suggests it's probably not effective.

For allergic rhinitis (hay fever), alopecia areata (patchy hair loss), and alcoholism, we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Pantothenic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pantothenic acid taken by mouth is generally well tolerated, with diarrhea reported in some cases. The amounts in food and standard prenatal vitamins are considered appropriate during pregnancy and breastfeeding, both rated likely safe.

However, because you're taking a high-dose supplement (1000 mg is well above typical dietary intake), talk with your doctor before starting it — especially if you're pregnant, breastfeeding, or considering high-dose use.

Side effects, ingredient by ingredient Pantothenic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for pantothenic acid. That said, run your medications through the checker on this page to be thorough, and let your doctor know you're starting this supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This supplement is straightforward: one active ingredient with no documented drug interactions and a strong track record for treating pantothenic acid deficiency. If you're looking to address a B5 deficiency or exploring it for other reasons, the safety profile is solid — but at this dose, it's worth confirming with your doctor or pharmacist that it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pantothenic Acid 1000 mg, straight from the product label.

Brand NaturesPlus
Barcode (UPC) 097467020603
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 298735
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pantothenic Acid 1000 mg by NaturesPlus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
097467020603
IngredientAmount% DV
Pantothenic Acid1000 mg20000%

Other ingredients: Stearic Acid, Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Rice Bran, Silica, Magnesium Stearate, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pantothenic acid (Vitamin B5) is known as the stress support vitamin, as it supports adrenal gland function, including production of adrenal hormones. It is used for production of immune defense antibodies, for vitamin utilization and for the conversion of macronutrients into energy. Pantothenic acid is required for hundreds of cell functions, including cellular metabolism.

Formulation

In a special base which provides for the gradual release of ingredients over prolonged period of time. MICRO-GEL sustained release system

Sustained release Stress support

Free from artificial colors and artificial preservatives. Free from all of the major allergens identified in the U.S. Food Allergen Labeling and Consumer Protection Act.

Vegetarian

Gluten free

Storage

Keep tightly closed in a cool, dry place.

Precautions

Keep out of reach of children.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: One tablet daily.

Brand IP Statement(s)

Copyright Natural Organics

See for yourself

Pantothenic Acid 1000 mg by NaturesPlus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pantothenic Acid 1000 mg by NaturesPlus

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Pantothenic Acid

No known
interactions
1000 mg per serving Form: Calcium Pantothenate

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

Other (inactive) ingredients: Stearic Acid, Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Rice Bran, Silica, Magnesium Stearate, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pantothenic Acid 1000 mg by NaturesPlus Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pantothenic Acid 1000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pantothenic Acid 1000 mg, from the product label.

NaturesPlus

See all NaturesPlus products
Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Pantothenic Acid 1000 mg by NaturesPlus: Common Questions

Does Pantothenic Acid 1000 mg by NaturesPlus interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pantothenic Acid 1000 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pantothenic Acid 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is pantothenic acid safe during pregnancy and breastfeeding?
Yes — pantothenic acid is rated likely safe during both pregnancy and breastfeeding. The amounts in food and standard prenatal vitamins are considered appropriate. However, because this is a 1000 mg high-dose supplement, check with your doctor before taking it at this strength.
What does pantothenic acid actually do?
Pantothenic acid (vitamin B5) helps your body convert food into energy and plays a role in making certain hormones and cholesterol. It's essential for normal function, though deficiency is rare in people eating a typical diet.
Will this help my hair loss or hay fever?
For patchy hair loss (alopecia areata), we don't have enough reliable evidence to say whether pantothenic acid helps. For hay fever (allergic rhinitis), we also lack solid evidence either way. If you're interested in trying it for one of these, talk it over with your doctor.
What are the side effects?
Orally, pantothenic acid is generally well tolerated. The main side effect reported is diarrhea. Most people have no problems with it.
Can I take this with my other supplements?
No documented interactions exist between pantothenic acid and other supplements in our data. Still, if you're on multiple supplements or medications, it's smart to check them all together with your pharmacist to make sure nothing overlaps in an unexpected way.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pantothenic Acid 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pantothenic Acid 1000 mg label
Go deeper

The Full Monographs Behind Pantothenic Acid 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pantothenic Acid 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pantothenic Acid 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
  5. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
  6. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
  7. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  8. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
  9. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
  10. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
  11. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed

See these in context on the Pantothenic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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