Pantothenic Acid 500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pantothenic Acid 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pantothenic Acid 500 mg is a dietary supplement by Nature's Plus with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pantothenic Acid 500 mg by Nature's Plus
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: pantothenic acid (vitamin B5) at 500 mg per capsule. Pantothenic acid is a B vitamin your body needs to make and break down fats and proteins, and to produce certain hormones and cholesterol.
The capsule also contains several inactive ingredients — vegetable cellulose, microcrystalline cellulose, rice bran, silica, magnesium stearate, and purified water — which serve as the capsule shell and fillers to hold everything together.
Does it work?
Strong evidence
Pantothenic acid is effective for treating pantothenic acid deficiency, which is rare in people eating a typical diet. For other uses listed here — radiation dermatitis, hay fever, alcoholism, and alopecia areata (hair loss) — the evidence isn't strong enough to establish whether it works.
The data we hold rates radiation dermatitis as possibly ineffective and the other three conditions as having insufficient reliable evidence to rate.
How safe is it?
Well-documented data
Pantothenic acid taken by mouth is generally well tolerated, with diarrhea reported in some cases. The safety data notes that amounts found in food and prenatal vitamins are fine, but advises you to check with your doctor before taking high-dose supplements like this one.
Pregnancy and breastfeeding: Pantothenic acid is rated likely safe during pregnancy and likely safe during lactation at normal dietary levels. Since this is a high-dose form, talk with your doctor or pharmacist about whether it's right for you during pregnancy or while breastfeeding.
Meds to double-check
No known interactions
No interactions are documented for pantothenic acid in our data. That said, because this is a high-dose supplement, it's worth mentioning it to your doctor or pharmacist — they can confirm it won't interfere with anything you're taking and that the dose is appropriate for you.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
This supplement is a good fit if you have a documented pantothenic acid deficiency or want to ensure you're getting adequate B5. Because it's a high-dose form, check with your doctor or pharmacist before starting — especially if you're pregnant, breastfeeding, or take regular medications.
No interactions are documented, but that's not a guarantee none exist; your own healthcare provider knows your full medical picture best.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pantothenic Acid 500 mg, straight from the product label.
| Brand | Nature's Plus |
|---|---|
| Barcode (UPC) | 097467020412 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 25, 2015 |
| DSLD ID | 49239 |
| Product type | Vitamin |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pantothenic Acid 500 mg by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pantothenic Acid | 500 mg | 5000% |
Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Rice Bran, Silica, Magnesium Stearate, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
(C)NATURAL ORGANICS(R)
Vcaps(TM) is a trademark of Capsugel(R)
The Energy Supplements(R)
Formula
High Potency - 100% Pure Crystalline Pantothenic Acid 500 mg
Hypo-Allergenic
Seals/Symbols
Vcaps(R)
GLUTEN Free
QUALITY NATURAL SUPPLEMENTS(R)
FDA Disclaimer Statement
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
Product No. 2041 LBL. 1133175
FDA Statement of Identity
Dietary Supplement
General Statements
Nutritional Support for Natural Energy Production.*
Formulation
Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, corn, soy and milk.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, one capsule daily.
Storage
KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pantothenic Acid 500 mg by Nature's Plus label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pantothenic Acid 500 mg by Nature's Plus
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Pantothenic Acid
No knowninteractions
Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...
Pantothenic Acid monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Rice Bran, Silica, Magnesium Stearate, Purified Water. These complete the product’s ingredient list but are not active constituents.
Pantothenic Acid 500 mg by Nature's Plus Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pantothenic Acid 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pantothenic Acid 500 mg, from the product label.
Nature's Plus
See all Nature's Plus products- Name
- Natural Organics Laboratories, Inc. makers of Nature's Plus
- Street Address
- 9500 New Horizons Blvd.
- City
- Amityville
- State
- New York
- ZipCode
- 11701
- Web Address
- www.naturesplus.com
Pantothenic Acid 500 mg by Nature's Plus: Common Questions
Does Pantothenic Acid 500 mg by Nature's Plus interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is pantothenic acid used for?
Can I take this while pregnant or breastfeeding?
What side effects should I watch for?
Is this safe to take long-term?
Does this product have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pantothenic Acid 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pantothenic Acid 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pantothenic Acid 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pantothenic Acid 11 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
- Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
- Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
- Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
- Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
- Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
- Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
- Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC