No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pantothenic Acid Ingredients & Drug Interactions

by Higher Nature

Pantothenic Acid label
See full label image
Capsule Category: Vitamin
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pantothenic Acid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Pantothenic Acid is a dietary supplement by Higher Nature with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Pantothenic Acid by Higher Nature

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pantothenic acid, also called vitamin B5. Pantothenic acid is a B vitamin your body uses to break down food for energy and to make and repair cells.

This single-ingredient capsule also includes inactive ingredients — the capsule shell, magnesium stearate, and silicon dioxide — which help hold and deliver the vitamin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: energy and normal energy yielding metabolism.
  • We looked for evidence on: Chronic fatigue syndrome (CFS), Pantothenic acid deficiency, fatigue, energy production.
  • The strongest evidence on file: Pantothenic Acid is rated "Effective" for Pantothenic acid deficiency (Natural Medicines).
  • Also on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS).

Pantothenic acid is effective for treating pantothenic acid deficiency, a genuine but rare shortage of this B vitamin. For radiation dermatitis (skin damage from radiation therapy), the evidence suggests it's probably ineffective.

For allergic rhinitis (hay fever), alopecia areata (patchy hair loss), and alcoholism, we don't have enough reliable evidence yet to say whether it works or doesn't.

The evidence, ingredient by ingredient Pantothenic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pantothenic acid taken by mouth is generally well tolerated, with few side effects — though diarrhea has been reported. If you're taking normal amounts from food or prenatal vitamins, that's fine.

Before you take high-dose supplements, check with your doctor, since safety data for larger amounts are more limited. Pantothenic acid is rated likely safe in pregnancy and lactation at standard doses.

Side effects, ingredient by ingredient Pantothenic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, run your exact medications through the tool on this page and mention this supplement to your doctor or pharmacist before you start, just to make sure.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward B vitamin supplement useful if you have a documented pantothenic acid deficiency — something your doctor can test for. At normal doses it's well tolerated and shows no documented interactions with medications.

If you're considering it for a specific health concern like hair loss or allergies, talk it over with your doctor or pharmacist first, since the evidence for those uses isn't firm yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pantothenic Acid, straight from the product label.

Brand Higher Nature
Barcode (UPC) 5031013102035
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 245750
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pantothenic Acid by Higher Nature, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
5031013102035
IngredientAmount% DV
Pantothenic Acid500 mg8333%

Other ingredients: Pantothenic Acid, Capsule Shell, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

NRV = Nutrient Reference Value

This product has not been tested on animals.

Healthy Lifestyle

Formulation

Free from: Artificial colours, flavourings or preservatives, corn, dairy products, gluten, lactose, maize, salt, soya, starch, sugar, wheat, yeast.

For tiredness & fatigue

Advanced formula Optimal benefit

Helps reduce tiredness and fatigue

FDA Statement of Identity

Food Supplement

Formula

Pantothenic acid (vitamin B5) contributes to normal energy yielding metabolism

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule a day, with meals. Do not exceed recommended daily intake. A daily multivitamin is also recommended.

Precautions

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

B vitamins may turn urine bright yellow - this is normal.

Storage: Store in a cool, dry place out of reach of children.

Storage

Storage: Store in a cool, dry place out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pantothenic Acid by Higher Nature label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pantothenic Acid label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pantothenic Acid by Higher Nature

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Pantothenic Acid

No known
interactions
500 mg per serving Form: Vitamin B5

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

Other (inactive) ingredients: Pantothenic Acid, Capsule Shell, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pantothenic Acid by Higher Nature Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pantothenic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pantothenic Acid, from the product label.

Higher Nature

See all Higher Nature products
Name
Higher Nature Ltd
Street Address
10 Discovery Way
City
Horam, East Sussex
ZipCode
TN21 0GE
Web Address
highernature.com
Pharmacist Counseling Corner

Pantothenic Acid by Higher Nature: Common Questions

Does Pantothenic Acid by Higher Nature interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pantothenic Acid. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pantothenic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is pantothenic acid safe to take if I'm pregnant or breastfeeding?
Yes — pantothenic acid is rated likely safe in pregnancy and lactation at normal dietary and prenatal-vitamin amounts. If you're thinking about taking a high-dose supplement, check with your doctor first.
What are the side effects?
Taken by mouth, pantothenic acid is generally well tolerated with few side effects. Diarrhea has been reported. If you apply it to your skin as a cream or lotion, it may cause itching, burning, irritation, or contact dermatitis in some people.
Will this help with hair loss?
We don't have enough reliable evidence to say whether pantothenic acid helps with alopecia areata (patchy hair loss). If that's why you're considering it, talk with your doctor about what the evidence shows and whether it makes sense for you.
What is pantothenic acid used for?
Pantothenic acid, or vitamin B5, helps your body break down food for energy and make and repair cells. It's effective for treating a genuine pantothenic acid deficiency, though that's rare.
Is it safe to take high-dose pantothenic acid?
Normal amounts from food and prenatal vitamins are fine. Before you take high-dose supplements, check with your doctor — the safety data for larger amounts are more limited, and you want personalized advice based on your health.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pantothenic Acid is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pantothenic Acid label
Go deeper

The Full Monographs Behind Pantothenic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph →
Sources

Sources & How We Checked

Pantothenic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pantothenic Acid 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
  5. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
  6. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
  7. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  8. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
  9. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
  10. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
  11. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed

See these in context on the Pantothenic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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