No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

PanXyme pH Ingredients & Drug Interactions

by XYMOGEN

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

PanXyme pH is a dietary supplement by XYMOGEN with 3 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of PanXyme pH by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.
  • “Newlase” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

PanXyme pH contains three active ingredients: protease, lipase, and amylase. These are digestive enzymes — proteins your body naturally produces to break down food.

Protease breaks down proteins, lipase handles fats, and amylase breaks down carbohydrates. The product also includes inactive ingredients like calcium carbonate and microcrystalline cellulose as fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Digestive enzyme support.
  • We looked for evidence on: Dyspepsia, Pancreatic insufficiency, Fat malabsorption, Indigestion.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is limited. Lipase has been studied for inflammatory bowel disease (IBD) and dyspepsia (indigestion), but the data we have rates it as insufficient to say whether it works.

No effectiveness ratings are on file for protease or amylase in this product. If you're considering PanXyme pH for a specific digestive issue, talk with your pharmacist or doctor about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated in most adults, though some people report digestive upset or allergic reactions. Protease can rarely trigger allergic reactions in people sensitive to enzymes — occupational exposure to similar enzymes has caused allergic rhinitis or asthma in some cases.

During pregnancy, protease is best avoided unless prescribed by your doctor. For lipase, there's little safety data in pregnancy, so use only if your doctor advises it.

Breastfeeding safety data is limited for both; check with your healthcare provider first. Lipase carries a rare serious warning for premature infants receiving a specific recombinant form, but that's not this product.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, run your exact medications through the search tool on this page before you start, just to be sure.

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

PanXyme pH is a digestive enzyme blend for people who want support breaking down food. It's generally well tolerated by most adults, but if you're pregnant, breastfeeding, or have a serious digestive condition, talk with your pharmacist or doctor first — the safety data is thin in those groups.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PanXyme pH, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 871149002336
Net contents 180 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 335542
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PanXyme pH by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
871149002336
IngredientAmount% DV
Protease0 NP--
Lipase10.2 mg--
Newlase10 mg--
Amylase45 mg--

Other ingredients: Calcium Carbonate, Microcrystalline Cellulose, Hypromellose, Water, Stearic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one capsule with or after each meal, or as directed by your healthcare professional.

Precautions

Consult your healthcare professional prior to use.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Do not use if tamper seal is damaged.

Storage: Keep closed in a cool, dry place out of reach of children.

Formula

PanXyme pH is a blend of digestive enzymes derived from the fermentation action of fungi such as Aspergillus niger and Rhizopus niveus, microorganisms safely used in fermenting foods, including cheese, soy sauce, and yogurt. These non-animal derived enzymes support the assimilation of nutrients in foods and the digestion of proteins, carbohydrates, fats, and vegetable matter.

Acid-Resistant, Nonanimal-Derived Digestive Enzymes

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Storage: Keep closed in a cool, dry place out of reach of children.

Formulation

Formulated to exclude: Gluten, yeast, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, and artificial sweeteners.

Vegetarian Caps

Brand IP Statement(s)

Copyright 2023 XYMOGEN

Xymogen Exclusive Professional Formulas

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

ePV (ePedigree Verification) GMP Compliant Third-Party Verified

General Statements

Scan to Learn More! This package is completely recyclable

See for yourself

PanXyme pH by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PanXyme pH by XYMOGEN

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lipase

No known
interactions
10.2 mg per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Newlase

10 mg per serving

Amylase

45 mg per serving Form: Biodiastase 2000

Other (inactive) ingredients: Calcium Carbonate, Microcrystalline Cellulose, Hypromellose, Water, Stearic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

PanXyme pH by XYMOGEN Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in PanXyme pH. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for PanXyme pH, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN Exclusive Professional Formulas
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

PanXyme pH by XYMOGEN: Common Questions

Does PanXyme pH by XYMOGEN interact with any medications?
We do not currently list a known interaction for the mapped ingredients in PanXyme pH. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
PanXyme pH contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What do these enzymes do?
Protease breaks down proteins, lipase breaks down fats, and amylase breaks down carbohydrates. Together, they're meant to help your body digest food more completely. They're enzymes your body makes naturally — this product just adds more.
Is PanXyme pH proven to work?
The evidence is limited. Lipase has been studied for indigestion and inflammatory bowel disease, but the data we have isn't strong enough to say it works. No solid evidence is on file for protease or amylase in this formulation.
Can I take this if I'm pregnant?
Not without talking to your doctor first. Protease should be avoided in pregnancy unless prescribed. Lipase has little safety data in pregnancy, so use only if your doctor advises it.
Is it safe while breastfeeding?
There's not enough safety data for either protease or lipase while breastfeeding. Check with your healthcare provider before you start.
What side effects might I have?
Most people tolerate it well. Some report digestive upset. Rarely, protease can trigger allergic reactions in people sensitive to enzymes — watch for rash, itching, or breathing trouble and stop if that happens.
Does this contain fillers?
Yes — it includes inactive ingredients like calcium carbonate, microcrystalline cellulose, and magnesium stearate as binders and fillers to hold the capsule together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PanXyme pH is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PanXyme pH label
Sources

Sources & How We Checked

PanXyme pH's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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