Pipsissewa Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Pipsissewa against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pipsissewa is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for urinary tract support, diuretic (increasing urine flow), mild inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pipsissewa by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Pipsissewa Aerial Parts Extract, Fresh. The extract comes from the above-ground parts of the pipsissewa plant and is prepared using alcohol and vegetable glycerin as the extraction base.
Beyond the extract itself, the product also contains certified organic cane alcohol and certified organic vegetable glycerin as inactive ingredients.
Does it work?
Couldn't assess
We hold no effectiveness data for pipsissewa in our monograph. The safety notes underscore that while traditional use is long-standing, modern scientific evidence on whether it actually works hasn't been established in the data we have.
How safe is it?
Well-documented data
Here's where you need to pause: chronic use of pipsissewa may lead to hydroquinone toxicity, a buildup of a compound that can cause tinnitus (ringing in the ears), vomiting, delirium, convulsions, and collapse. Modern safety data on this herb is limited, and it's not recommended during pregnancy or while breastfeeding because we don't have enough reliable information to know either way.
If you're pregnant, nursing, or thinking about long-term use, talk with your pharmacist or doctor first.
Meds to double-check
No known interactions
No interactions are documented in our data for pipsissewa. That doesn't mean none exist — it means we haven't found them — so run your medications through the checker below before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Pipsissewa has a long history of traditional use, but modern safety and effectiveness evidence are sparse. The main concern is potential hydroquinone toxicity with chronic use.
This isn't a product to take long-term without professional guidance — if you're considering it, check in with your pharmacist or doctor, especially if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pipsissewa, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700002053 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 275369 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pipsissewa by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pipsissewa Aerial Parts Extract, Fresh | 659 mg | -- |
Other ingredients: certified organic Cane Alcohol, certified organic Vegetable Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use Shake well before using Adults: Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.
Precautions
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Chimaphila umbellata
Pipsissewa liquid extract
We prepare our Pipsissewa extract from the fresh (undried) aerial parts of Chimaphila umbellata plants which are responsibly wildcrafted in their natural habitat.
Formulation
System restoration Urinary
Gluten-free
Fresh herb/menstruum ratio: 1:1.75
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pipsissewa by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pipsissewa by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.
Pipsissewa Aerial Parts Extract, Fresh
No knowninteractions
Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very...
Pipsissewa Aerial Parts Extract, Fresh monograph & interactionsOther (inactive) ingredients: Certified organic Cane Alcohol, Certified organic Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.
Pipsissewa by Herb Pharm Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pipsissewa. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pipsissewa, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Pipsissewa by Herb Pharm: Common Questions
Does Pipsissewa by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant?
Is it safe to take while breastfeeding?
What happens if I use it for a long time?
Does this actually work?
What is pipsissewa used for traditionally?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pipsissewa is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pipsissewa’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pipsissewa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 1 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pipsissewa 1 reference
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC