POISE By Core Nutritionals Overview & Drug Interactions

Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.

Iodine is a mineral that is crucial for our body's ability to produce thyroid hormone, which helps control our growth, metabolism, and energy levels. A lack of iodine in the diet is a common problem around the world and can lead to intellectual development issues. Adding iodine to salt (i.e., iodized salt) has helped reduce this problem. Iodine is commonly utilized as a dietary supplement, both in multivitamin preparations and as a standalone ingredient as it is purported to have overall health and wellness benefits, not just in those who are deficient. One such standalone iodine product is 'Iodoral'. Studies have shown iodine supplementation may help improve cognitive function and boost energy levels but more research is needed. It is recommended that you should be under medical supervision if you plan on taking iodine as there may be a risk of certain side effects with high dosages.

L-tyrosine is a non-essential amino acid produced within the body through the conversion of the essential amino acid, phenylalanine. It is often used as a dietary supplement to support cognitive function, enhance focus, and mitigate stress by serving as a precursor for neurotransmitters like dopamine and norepinephrine.

Turmeric is a commonly used spice and a member of the ginger family (Zingiberaceae). It is native to India and other parts of South Asia and is known for its bright orange-yellow color and its warm, slightly bitter flavor. In traditional medicine, turmeric is believed to have a number of health benefits due to its high content of antioxidants and other compounds, such as curcumin. It is thought to have anti-inflammatory and antimicrobial properties, and it is often used to treat a variety of conditions, including joint pain, digestive problems, skin disorders, and respiratory infections. Most dietary supplements that utilize turmeric standardize their products based on a specific amount of curcumin (curcuminoids) per dose. Additionally, turmeric supplements are often paired with black pepper extract (piperine) to improve oral absorption.

Olive contains compounds like polyphenols, particularly hydroxytyrosol and oleuropein, which have antioxidant properties that can help combat oxidative stress in the body. Olive supplements may support heart health by reducing LDL cholesterol and blood pressure. Additionally, they may have anti-inflammatory effects and potentially aid in weight management.

Glutathione is a naturally occurring compound that is composed of three amino acids: cysteine, glutamic acid, and glycine. It is found in nearly all cells in the body and plays a crucial role in many physiological processes, including as an antioxidant defense, detoxification, and immune function. Glutathione levels in the body can be decreased by a number of factors, such as aging, stress, poor diet, and exposure to toxins. Some people take glutathione supplements in the hopes of increasing their levels and potentially benefiting from its antioxidant properties. Glutathione supplements are available in various forms, including oral supplements, intravenous (IV) injections, and nebulized (inhaled) forms. Oral glutathione supplements are often in a liposomal form to improve absorption.

Diindolylmethane (DIM) is a compound found in cruciferous vegetables such as broccoli, cabbage, and kale. It is formed during the digestion of indole-3-carbinol, another compound found in these vegetables. DIM has been studied for its potential health benefits, including improved hormone balance and reduced risk of certain cancers. DIM (Diindolylmethane) supplements are often marketed as a natural way to support hormone balance, specifically estrogen imbalances, and as a 'detoxifying agent'. Supplements with DIM are often paired with Bioperine to improve absorption.

Pregnenolone is a hormone that is produced naturally in the body by the adrenal glands as well as in the brain. It is a precursor to other hormones, including cortisol, progesterone, testosterone, dehydroepiandrosterone (DHEA), and estrogens, and plays a role in a number of bodily functions. Pregnenolone is often utilized as a dietary supplement and is purported to have a number of potential health benefits, including improved memory and cognitive function, reduced anxiety and stress, and enhanced immune function. Pregnenolone is also used for its supposed anti-aging properties.

Black pepper is a spice made from the dried, unripe fruit of the Piper nigrum plant, which is native to the southwestern coast of India. It is one of the most widely used spices in the world, and it is often utilized to add flavor and heat to a wide variety of dishes. In traditional medicine, black pepper is purported to have a number of health benefits. It is a good source of antioxidants and is thought to have anti-inflammatory properties, which may make it useful in reducing inflammation and swelling in the body. Black pepper is also used as a natural remedy for digestive problems, such as indigestion and bloating, and to boost the immune system. Black pepper is widely used in dietary supplements, specifically, an extract from black pepper known as piperine. Piperine can affect the absorption of many drugs, which is why it has a large number of reported interactions. Oftentimes, these 'interactions' are purposeful, such as when piperine is used with turmeric, to increase its absorption.