Pro-Digestion Intensive Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pro-Digestion Intensive against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pro-Digestion Intensive is a dietary supplement by Seeking Health with 6 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pro-Digestion Intensive by Seeking Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Pro-Digestion Intensive contains 18 active ingredients, most of them digestive enzymes that break down different types of food. You've got carbohydrate-digesting enzymes (amylase, glucoamylase, maltase, sucrase, alpha-amylase), fat-digesting lipase, protein-digesting enzymes (acid protease, alkaline protease, serratia peptidase), and lactase for breaking down milk sugar.
There's also phytase, which helps with mineral absorption, and fiber-specific enzymes like cellulase, hemicellulase, and pectinase. The product includes several enzyme blends organized by what they're meant to target: carbohydrates, sugars, plant fiber, proteins, and fats.
Inactive ingredients are xylitol, mannitol, stearic acid, silicon dioxide, and natural cherry flavor.
Does it work?
Strong evidence
The evidence for most ingredients in this product isn't yet established in the data we hold. Lactase is rated effective for lactose intolerance—if that's what you're after, this product has it.
The others—lipase, acid protease, alkaline protease, and phytase—have insufficient reliable evidence to rate them for any condition. That doesn't mean they don't work; it means studies haven't been robust enough yet to say one way or the other.
If you're using this for general digestive support or a specific condition, talk it over with your doctor or pharmacist about whether the evidence fits your situation.
How safe is it?
Well-documented data
Lipase, lactase, and the protease enzymes are generally well tolerated in adults when used as directed. One rare allergic reaction to powdered lactase has been reported in an occupational setting.
The protease enzymes—acid protease, alkaline protease, and the protease/peptidase complex—can occasionally cause digestive upset or allergic reactions, and there are rare case reports of allergic rhinitis or asthma from airborne occupational exposure to pepsin. Phytase is considered low-risk in food but has limited human supplement safety data; occupational exposure to airborne phytase powder has caused allergic asthma and hypersensitivity pneumonitis in some workers.
Pregnancy and breastfeeding safety varies by ingredient: lipase has little safety data in pregnancy or while breastfeeding and should be used only with your doctor's advice; lactase is likely safe in pregnancy but check with your doctor first; the proteases and phytase lack established safety data and should be avoided in pregnancy unless prescribed, and breastfeeding safety isn't well studied for any of them.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, several enzymes in this product—amylase, cellulase, glucoamylase, alpha-galactosidase, maltase, beta-glucanase, alpha-amylase, sucrase, pullulanase, galactomannose, serratia peptidase, and the hemicellulase/pectinase/phytase complex—we don't have interaction data for.
Check with your pharmacist or doctor before taking this product with any prescription medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a multi-enzyme digestive supplement with no documented drug interactions for the ingredients we could check, though we couldn't verify several of the enzymes against our database. Lactase is the only ingredient with solid evidence of effectiveness—for lactose intolerance specifically.
If you're taking medications, run your list through our search tool before starting, and talk with your doctor or pharmacist about whether this product makes sense for what you're trying to do.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 18 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pro-Digestion Intensive, straight from the product label.
| Brand | Seeking Health |
|---|---|
| Barcode (UPC) | 828054148130 |
| Net contents | 180 Chewable Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jan 25, 2020 |
| DSLD ID | 211082 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pro-Digestion Intensive by Seeking Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Maltase | 0 NP | -- |
| Acid Protease | 0 NP | -- |
| Beta-Glucanase | 0 NP | -- |
| Phytase | 0 NP | -- |
| Alpha-Amylase | 0 NP | -- |
| Sucrase | 0 NP | -- |
| Alkaline Protease | 0 NP | -- |
| Comprehensive Enzyme Blend | 320 mg | -- |
| Carbohydrate Specific Enzymes | 0 NP | -- |
| Sugar Specific Enzymes | 0 NP | -- |
| Pullulanase | 0 NP | -- |
| Vegetable/Plant Fiber Specific Enzymes | 0 NP | -- |
| Galactomannase | 0 NP | -- |
| Protein and Peptide Specific Enzymes | 0 NP | -- |
| Fat Specific Enzymes | 0 NP | -- |
| Other Enzymes | 0 NP | -- |
| Hemicellulase/Pectinase/Phytase Complex | 0 NP | -- |
| Protease/Peptidase Complex | 0 NP | -- |
| Serratia peptidase | 0 NP | -- |
Other ingredients: Xylitol, Mannitol, Stearic Acid, Silicon Dioxide, natural Cherry flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Targeted Support
Units are those used in edition nine (IX) of the Food Chemicals Codex (FCC)
Pro-Digestion Intensive meets or exceeds cGMP Quality Standards.
Find other effective health products at: www.SeekingHealth.com
FDA Statement of Identity
Comprehensive Enzyme Supplement
Formulation
Does Not Contain: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
Suggested/Recommended/Usage/Directions
Suggested Use: 2 tablets at the beginning of each meal or as directed by your healthcare professional.
Precautions
Do not use if shrinkwrap is broken or missing.
Keep out of reach of children.
Storage
Storage: Store in a cool, dry place below 85 degrees F away from direct light. Do not freeze.
Brand IP Statement(s)
Peptizyme SP, a registered trademark of Specialty Enzymes.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pro-Digestion Intensive by Seeking Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pro-Digestion Intensive by Seeking Health
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Comprehensive Enzyme Blend
- › Carbohydrate Specific Enzymes
- › Sugar Specific Enzymes
- › Vegetable/Plant Fiber Specific Enzymes
- › Protein and Peptide Specific Enzymes
- › Fat Specific Enzymes
- › Other Enzymes
Other (inactive) ingredients: Xylitol, Mannitol, Stearic Acid, Silicon Dioxide, Natural Cherry flavor. These complete the product’s ingredient list but are not active constituents.
Pro-Digestion Intensive by Seeking Health Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pro-Digestion Intensive. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pro-Digestion Intensive, from the product label.
Seeking Health
See all Seeking Health products- Name
- Seeking Health, LLC
- Street Address
- 3140 Mercer Ave
- City
- Bellingham
- State
- WA
- ZipCode
- 98225
- Phone Number
- (800) 547-9812
- Web Address
- www.seekinghealth.com
Pro-Digestion Intensive by Seeking Health: Common Questions
Does Pro-Digestion Intensive by Seeking Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to use while I'm pregnant?
Can I use this while breastfeeding?
What is lactase, and does it actually work?
Will this cause side effects?
What are proteases, and why are they in this?
Do I need to worry about interactions with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pro-Digestion Intensive is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
Pro-Digestion Intensive's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC