No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pure Citric Acid Pharma Grade Powder Ingredients & Drug Interactions

by Hard Rhino

Powder Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Pure Citric Acid Pharma Grade Powder is a dietary supplement by Hard Rhino with 1 active ingredient. Its ingredients are commonly taken for food and drink flavoring or sourness, preservative and acidity adjuster, kidney stone prevention (as citrate salts).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pure Citric Acid Pharma Grade Powder by Hard Rhino

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is pure citric acid — one active ingredient in powder form. It's a pharma-grade version, meaning it meets pharmaceutical manufacturing standards for purity.

The product contains only this one component; there are no other active ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Citric Acid product and its label doesn't state a use — see Citric Acid's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish citric acid's effectiveness for any of the uses it's marketed for — acne, aging skin, dry mouth, kidney stones, melasma, or muscle cramps. For each of these, the data shows insufficient reliable evidence to rate whether it works.

That doesn't mean it's ineffective, just that we don't have the study data to confirm it yet.

The evidence, ingredient by ingredient Citric Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Citric acid is generally recognized as safe in the small amounts found in foods and everyday supplements. However, the facts advise you to check with your doctor before using concentrated citrate supplements or taking medicinal doses, since this is a pharma-grade powder and not a typical food amount.

When applied to skin, it's usually well tolerated, though it can cause mild irritation, sun sensitivity, and tingling. High concentrations or prolonged contact can cause burns, blistering, and severe skin damage — rare, but serious.

Alpha hydroxy acids like citric acid also increase your skin's sensitivity to sun exposure and UV light, which may increase skin damage over time.

Side effects, ingredient by ingredient Citric Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for citric acid. Still, because this is a concentrated supplement form, check with your doctor or pharmacist before combining it with your medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a pure citric acid powder for people who want a concentrated source of the ingredient, but we don't yet have solid evidence it works for any specific health claim. If you're considering it for a particular reason, talk it over with your doctor or pharmacist first — especially if you're taking any medications or planning to use it in high doses rather than typical food amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Citric Acid Pharma Grade Powder, straight from the product label.

Brand Hard Rhino
Net contents 500 Gram(s); 1.1 lb
Market status On market
Date entered into DSLD Jun 25, 2014
DSLD ID 34289
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Citric Acid Pharma Grade Powder by Hard Rhino, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2000 mg
Maximum serving Sizes:
2000 mg
Servings per container
250
IngredientAmount% DV
Citric Acid2000 mg--

Other ingredients: Citric Acid USP Pharma Grade Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep away from children.

Do not take this or any other supplement if you are pregnant or nursing, have high blood pressure or taking other prescription drugs.

WARNING: A micro scale is required for accurate measurements.

General Statements

Always consult with a physician before taking any new dietary supplement.

Quality Healthcare Worldwide

Expiration date on back of pouch.

USP-FCC

This is a NON-GMO ingredient produced with organic material.

Formulation

No added fillers No flow agents No driers No other ingredients

Allergens: This product contains NO Soy, Milk & Byproducts, Eggs, Fish, Shellfish, Wheat, Gluten, Tree Nuts, or Sesame Seeds.

Storage

Storage: Store in a cool & dry place. Keep away from strong light & heat.

Storage: Store in a cool & dry place. Keep away from direct sunlight and heat.

Suggested/Recommended/Usage/Directions

Suggested Use: Food grade acid used to reduce spoilage is sprouting by adding 1 tsp. per quart to soak and rinse water.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.

See for yourself

Pure Citric Acid Pharma Grade Powder by Hard Rhino label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pure Citric Acid Pharma Grade Powder by Hard Rhino

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2000 mg Dosage formPowder Servings per container250 Amounts shown are per serving.

Citric Acid

No known
interactions
2000 mg per serving

Citric acid is a natural acid found in citrus fruits and is widely used as a safe food additive, flavoring, and preservative. In medicine, citrate for...

Citric Acid monograph & interactions

Other (inactive) ingredients: Citric Acid USP Pharma Grade Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Citric Acid Pharma Grade Powder by Hard Rhino Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pure Citric Acid Pharma Grade Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pure Citric Acid Pharma Grade Powder, from the product label.

Hard Rhino

See all Hard Rhino products
Name
GUARDIAN Biosciences
City
Phoenix
State
Arizona
Pharmacist Counseling Corner

Pure Citric Acid Pharma Grade Powder by Hard Rhino: Common Questions

Does Pure Citric Acid Pharma Grade Powder by Hard Rhino interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pure Citric Acid Pharma Grade Powder. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pure Citric Acid Pharma Grade Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
The safety data we have rates citric acid as likely safe during pregnancy and lactation. That said, since this is a concentrated powder and not a typical food amount, it's worth confirming with your doctor or pharmacist before you start.
What does citric acid actually do?
We hold six possible uses — acne, aging skin, dry mouth, kidney stones, melasma, and muscle cramps — but the evidence we have for each of these isn't strong enough yet to say whether it works.
Can I use this on my skin?
Citric acid is often used in skincare products, and when applied topically it's generally well tolerated. However, it can cause mild irritation, sun sensitivity, and tingling. High concentrations can cause serious burns and blistering, so always test a small area first and avoid long contact times. Because it increases sun sensitivity, use sunscreen if you're applying it to exposed skin.
Are there any side effects I should know about?
Most topical side effects are mild — irritation, tingling, and increased sun sensitivity. Serious effects like burns, blistering, and skin damage are rare but can happen with high concentrations or prolonged contact. When taken by mouth in concentrated doses, you should check with your doctor first since food amounts are considered fine but medicinal doses need approval.
What are the inactive ingredients?
The product lists citric acid USP pharma grade powder as an inactive ingredient, meaning the rest of the powder is citric acid itself — no fillers or binders added.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Citric Acid Pharma Grade Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Citric Acid Pharma Grade Powder label
Go deeper

The Full Monographs Behind Pure Citric Acid Pharma Grade Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pure Citric Acid Pharma Grade Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Citric Acid 10 references
  1. Kurtzweil P. Alpha-hydroxy acids for skin care: Smooth sailing or rough seas? FDA 1999. Available at: /www.fda.gov/fdac/features/1998/298_ahas.html (Accessed 18 August 2000). DOI
  2. Erbagci Z, Akcali C. Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. Int J Dermatol 2000;39:789-94.. PubMed
  3. Ghadishah D, Gorchynski J. Airway compromise after routine alpha-hydroxy facial peel administration. J Emerg Med 2002;22:353-5.. PubMed
  4. Baumann LS, Oresajo C, Yatskayer M, Dahl A, Figueras K. Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment
  5. Emtestam L, Svensson Å, Rensfeldt K. Treatment of seborrhoeic dermatitis of the scalp with a topical solution of urea, lactic acid, and propylene glycol (K301): results of two double-blind, randomised, placebo-controlled studies. Mycoses. 2012 Sep;55(5):3 PubMed
  6. Kaminaka C, Uede M, Matsunaka H, Furukawa F, Yamomoto Y. Clinical evaluation of glycolic acid chemical peeling in patients with acne vulgaris: a randomized, double-blind, placebo-controlled, split-face comparative study. Dermatol Surg. 2014 Mar;40(3):314- PubMed
  7. Köse O, Özmen I, Arca E. An open, comparative study of 10% potassium hydroxide solution versus salicylic and lactic acid combination in the treatment of molluscum contagiosum in children. J Dermatolog Treat. 2013 Aug;24(4):300-4. PubMed
  8. Vachiramon V, Sahawatwong S, Sirithanabadeekul P. Treatment of melasma in men with low-fluence Q-switched neodymium-doped yttrium-aluminum-garnet laser versus combined laser and glycolic acid peeling. Dermatol Surg. 2015 Apr;41(4):457-65. PubMed
  9. US Food and Drug Administration (FDA). Cosmetic Ingredients: Alpha Hydroxy Acids. August 2020. Available at: https://www.fda.gov/cosmetics/cosmetic-ingredients/alpha-hydroxy-acids. Accessed on October 19, 2021.
  10. Ormerod AD, van Voorst Vader PC, Majewski S, Vanscheidt W, Benjamin N, van der Meijden W. Evaluation of the efficacy, safety, and tolerability of 3 dose regimens of topical sodium nitrite with citric acid in patients with anogenital warts: A randomized cl DOI

See these in context on the Citric Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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