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Dietary supplement

Pure LongJack 200:1 Extract Ingredients & Drug Interactions

by Micro Ingredients

Pure LongJack 200:1 Extract label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure LongJack 200:1 Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure LongJack 200:1 Extract is a dietary supplement by Micro Ingredients with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Longjack P.E.. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure LongJack 200:1 Extract by Micro Ingredients

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure LongJack 200:1 Extract by Micro Ingredients — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure LongJack 200:1 Extract by Micro Ingredients

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Longjack (Eurycoma longifolia root extract, concentrated 200:1). That means the powder is a concentrated form of the plant material — 200 parts of the original plant reduced down to 1 part extract.

The product has no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: male sexual health and testosterone support.
  • We looked for evidence on: Age-related testosterone deficiency, Erectile dysfunction (ED), Male Infertility, Sexual desire, Muscle strength, Athletic performance — and 3 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Muscle strength, Age-related testosterone deficiency, Male Infertility.

The evidence for Longjack is mixed. It's rated possibly effective for sexual desire, based on the research we have.

For athletic performance, the evidence suggests it's possibly ineffective. As for back pain, osteoporosis, and diabetes, we don't have enough reliable data to rate whether it works for those.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Longjack is generally well tolerated in short-term studies, but long-term safety data and quality control for supplements are uncertain. The adverse effects to watch are testosterone-related: if levels rise beyond normal, you could experience acne, insulin resistance, liver toxicity, and other testosterone-related side effects.

During pregnancy, the evidence advises against use due to limited safety data and possible hormonal effects. While breastfeeding, there's no reliable safety information, so it's best to avoid it.

Talk with your own doctor or pharmacist about your personal situation.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your own doctor or pharmacist before taking this if you're on propranolol (a blood-pressure or heart medication) — Longjack can reduce how well it works. Also discuss it if you take any drugs processed by your liver (CYP1A2, CYP2C19, or CYP2A6 substrates) or testosterone replacement therapy.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Longjack may help with sexual desire, but it interacts with blood-pressure medications and may affect how your liver processes many other drugs. If you take propranolol or any medication your doctor says is processed by your liver, you'll need to clear this with your own pharmacist or doctor before starting.

Pregnant people and those breastfeeding should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure LongJack 200:1 Extract, straight from the product label.

Brand Micro Ingredients
Barcode (UPC) X0016XTYCV
Net contents 100 Gram(s); 3.53 Oz(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 231746
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure LongJack 200:1 Extract by Micro Ingredients, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.35 Gram(s)
Maximum serving Sizes:
0.35 Gram(s)
Servings per container
286
UPC/BARCODE
X0016XTYCV
IngredientAmount% DV
Longjack P.E.350 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement Powder

Formula

Kosher

Formulation

Vegan

Non-GMO No preservatives Additives free Fillers free Gluten-free

Free of: soy, dairy, yeast, gluten & additives.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 scoop twice daily. A 5 days on, 2 days off cycle is recommended. For best results, please consult your physician.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

If pregnant/lactating or taking any medications, please consult your physician prior to use.

Keep out of the reach of children.

Storage

Keep in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure LongJack 200:1 Extract by Micro Ingredients label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure LongJack 200:1 Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure LongJack 200:1 Extract by Micro Ingredients

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.35 Gram(s) Dosage formPowder Servings per container286 Amounts shown are per serving.

Longjack P.E.

Interacts with
248 drugs
350 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Longjack P.E. monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure LongJack 200:1 Extract by Micro Ingredients Drug Interactions

Want to check YOUR meds against Pure LongJack 200:1 Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Longjack P.E. 248

Individual Drug Interactions

The ingredients in Pure LongJack 200:1 Extract interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure LongJack 200:1 Extract interact with drugs. Each result below shows which ingredient is responsible. Longjack P.E.

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure LongJack 200:1 Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Longjack P.E.5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Longjack P.E. full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure LongJack 200:1 Extract, from the product label.

Micro Ingredients

See all Micro Ingredients products
Name
Micro Ingredients
Street Address
21660 Copley Dr.
City
Diamond Bar
State
CA
ZipCode
91765
Phone Number
1-844-836-8200
Web Address
www.microingredients.com
Pharmacist Counseling Corner

Pure LongJack 200:1 Extract by Micro Ingredients: Common Questions

Does Pure LongJack 200:1 Extract by Micro Ingredients interact with any medications?
Yes. Based on its ingredients, Pure LongJack 200:1 Extract has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure LongJack 200:1 Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Longjack actually work for sexual desire?
The evidence rates it as possibly effective for that purpose, so there's some support in studies, though results aren't guaranteed for everyone. Your own doctor or pharmacist can help you decide if it's worth a try for your situation.
Can I take this while pregnant?
No. There isn't enough safety data and there are possible hormonal effects, so the safety notes advise against use during pregnancy. Talk with your doctor about alternatives.
What are the testosterone-related side effects I should watch for?
If Longjack raises your testosterone beyond the normal range, you could develop acne, insulin resistance, liver problems, and other testosterone-related effects. Those are reasons to be careful, especially if you're already on testosterone therapy.
Is this supplement safe long-term?
Short-term studies show it's generally well tolerated, but we don't have good long-term safety data or certainty about product quality across different brands. If you're thinking of taking it regularly, check in with your own pharmacist or doctor.
Does it work for athletic performance?
The evidence rates it as possibly ineffective for that — meaning studies don't support using it to boost athletic performance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure LongJack 200:1 Extract is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure LongJack 200:1 Extract label
Go deeper

The Full Monographs Behind Pure LongJack 200:1 Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Pure LongJack 200:1 Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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