No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Pygeum Extract Ingredients & Drug Interactions

by The Vitamin Shoppe

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum Extract is a dietary supplement by The Vitamin Shoppe with 2 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum Extract by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients, both forms of pygeum: pygeum africanum powder and pygeum bark extract. Pygeum is a plant extract traditionally used to support prostate health.

The capsules also hold inactive ingredients (rice flour, dicalcium phosphate, gelatin, magnesium stearate, and calcium silicate) that serve as fillers and binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: prostate health support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), urinary symptoms, prostate function.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum is likely effective for benign prostatic hyperplasia (BPH) — the non-cancerous enlargement of the prostate that can cause urinary symptoms in men. The evidence is stronger here than for its other traditional uses.

For Alzheimer disease, sexual desire, malaria, and psychosis, the evidence we have is insufficient to rate whether it works. Those uses remain unproven.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum is generally well tolerated in short-term use. A small number of people in clinical trials experienced nausea or abdominal pain, but those rates matched placebo, so it's hard to pin the symptoms on the herb itself.

The catch is that long-term and overall safety data are limited, so we're working with a narrower picture than we'd like. This product is meant for men's prostate health and shouldn't be used in pregnancy — there's no established safe use.

Breastfeeding is also best avoided because there isn't enough safety information. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pygeum Extract is a reasonable choice if you're a man dealing with prostate enlargement symptoms and want a plant-based option. The evidence backs its use for that purpose.

Just keep in mind that long-term safety data are sparse, so it's wise to discuss it with your doctor or pharmacist, especially if you're on other medications or have health concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum Extract, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536016617
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 204010
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum Extract by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
766536016617
IngredientAmount% DV
Pygeum africanum powder25 mg--
Pygeum bark extract25 mg--

Other ingredients: Rice Flour, Dicalcium Phosphate, Gelatin, Magnesium Stearate, Calcium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Standardized to 25% phytosterols

Prostate

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free Dairy free Soy free Nut free

Does not contain: Gluten, sugar, salt, artificial colors or flavors.

General Statements

This product may vary in color.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsule two (2) times daily, preferably with meals.

Precautions

Warning: Consult your healthcare provider prior to use if you are taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Storage

Store in a cool, dry place.

Seals/Symbols

Quality Promise Tested Trusted Guaranteed 30 day money back guarantee

See for yourself

Pygeum Extract by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum Extract by The Vitamin Shoppe

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pygeum africanum powder

No known
interactions
25 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum africanum powder monograph & interactions

Pygeum bark extract

No known
interactions
25 mg per serving Form: Phytosterols

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum bark extract monograph & interactions

Other (inactive) ingredients: Rice Flour, Dicalcium Phosphate, Gelatin, Magnesium Stearate, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum Extract by The Vitamin Shoppe Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum Extract, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Pygeum Extract by The Vitamin Shoppe: Common Questions

Does Pygeum Extract by The Vitamin Shoppe interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum Extract. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum Extract contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pygeum used for?
Pygeum is used mainly for benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate that can cause urinary problems in men. It's the condition for which the evidence is strongest. It's also been used traditionally for other purposes, but those uses don't have solid evidence behind them yet.
Does pygeum actually work?
For BPH, yes — pygeum is likely effective based on the research we have. For other uses like Alzheimer disease or sexual desire, the evidence is too thin to know whether it works, so those claims remain unproven.
What are the side effects?
Some people in trials reported nausea or stomach pain, but the rate was the same as placebo, so it's unclear whether pygeum caused them. Overall, it's been well tolerated in short-term use, though long-term safety data are limited.
Can I take this if I'm pregnant or breastfeeding?
No. Pygeum is designed for men's prostate health and has no established safe use in pregnancy. There isn't enough safety data for breastfeeding either, so it's best avoided. Talk with your doctor or pharmacist if you have questions.
Are there any fillers or inactive ingredients?
Yes, the capsule contains rice flour, dicalcium phosphate, gelatin, magnesium stearate, and calcium silicate — these are inactive binders and fillers that hold the product together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum Extract label
Go deeper

The Full Monographs Behind Pygeum Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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