SAMe 200 mg + Cofactors By Metabolic Maintenance Overview & Drug Interactions
Check For Interactions With SAMe 200 mg + Cofactors
Supplement: SAMe 200 mg + Cofactors by Metabolic Maintenance
SAMe 200 mg + Cofactors Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
Vitamin B6
| Ingredient Group | Vitamin B6 |
|---|---|
| Category | vitamin |
- Pyridoxal 5-Phosphate
Folate
| Ingredient Group | Vitamin B9 (Folate) |
|---|---|
| Category | vitamin |
-
Calcium L-5-Methylfolate
Description:Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium
Ingredient Group Vitamin B9 (calcium methylfolate) Category vitamin
Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.
See More Information Regarding Vitamin B12| Ingredient Group | Vitamin B12 |
|---|---|
| Category | vitamin |
- Methylcobalamin
Calcium
Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium| Ingredient Group | Calcium |
|---|---|
| Category | mineral |
- Calcium Citrate
Magnesium
Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.
See More Information Regarding Magnesium| Ingredient Group | Magnesium |
|---|---|
| Category | mineral |
- Magnesium Bisglycinate
SAMe
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
-
S-Adenosyl-L-Methionine Disulfate P-Toluenesulfonate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Calcium Chloride
Description:Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium
Ingredient Group Calcium Category mineral
Calcium Oxide
Description:Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium
Ingredient Group Calcium Category mineral
Drugs that interact with SAMe 200 mg + Cofactors by Metabolic Maintenance
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Capsule(s)
|
| Maximum serving Sizes: |
2 Capsule(s)
|
| Servings per container | 60 |
| UPC/BARCODE | 838287001560 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| Vitamin B6 |
2 mg
|
Vitamin B6 |
118%
|
| Folate |
333 mcg DFE
|
Vitamin B9 (Folate) |
83%
|
| Calcium L-5-Methylfolate |
200 mcg
|
Vitamin B9 (calcium methylfolate) |
|
| Vitamin B12 |
500 mcg
|
Vitamin B12 |
20833%
|
| Calcium |
20 mg
|
Calcium |
2%
|
| Magnesium |
20 mg
|
Magnesium |
5%
|
| SAMe |
200 mg
|
SAMe |
--
|
| S-Adenosyl-L-Methionine Disulfate P-Toluenesulfonate |
444 mg
|
SAMe |
|
| Calcium Chloride |
0 NP
|
Calcium |
|
| Calcium Oxide |
0 NP
|
Calcium |
|
| Other Ingredients: |
L-Leucine
Vegetarian Cellulose
Gellan Gum
|
|---|
Label Statments:
| Precautions |
- Caution: Pregnant or lactating women, consult your healthcare professional before taking this product.
- If you suffer from bipolar (manic) depression, do not use this product.
- Keep tightly closed in a cool, dry place, out of the reach of children.
|
|---|---|
| Storage |
- Keep tightly closed in a cool, dry place, out of the reach of children.
|
| Formulation |
- Moisture sensitive formula.
- Egg free
Gluten free
Free of nuts
Dairy free
- Manufactured in a GMP Compliant Facility
|
| Suggested/Recommended/Usage/Directions |
- Best consumed within 90 days after opening.
- Directions: One to two (1-2) capsules daily, between meals, or as directed by a healthcare professional.
|
| FDA Statement of Identity |
- Dietary Supplement
|
Brand Information
See all products by this brand
| Manufacturer | |
|---|---|
| Name | Metabolic Maintenance |
| Street Address | 601 N Larch Street |
| City | Sisters |
| State | Oregon |
| ZipCode | 97759 |
| Phone Number | 800-772-7873 |
| Web Address | MetabolicMaintenance.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.