SAMe 400 mg By Life Extension Overview & Drug Interactions
Check For Interactions With SAMe 400 mg
Supplement: SAMe 400 mg by Life Extension
SAMe 400 mg Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosyl-Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
Drugs that interact with SAMe 400 mg by Life Extension
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Enteric Coated Tablet(s)
|
| Maximum serving Sizes: |
1 Enteric Coated Tablet(s)
|
| UPC/BARCODE | 737870193463 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| S-Adenosyl-Methionine |
400 mg
|
SAMe |
--
|
| Other Ingredients: |
Cellulose
Mannitol
Hydroxypropyl Methylcellulose Phthalate
Citric Acid
Stearic Acid
Silica
Glyceryl Triacetate
Sodium Starch Glucolate
Croscarmellose Sodium
Titanium Dioxide
yellow Ochre
|
|---|
Label Statments:
| Suggested/Recommended/Usage/Directions |
- Directions: Take one (1) tablet two to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner. Take with co-factors vitamins B12, B6, and folic acid.
|
|---|---|
| Precautions |
- Caution: SAMe should not be taken by those diagnosed with bipolar disorder.
- Warnings - Keep out of reach of children.
- - When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
|
| Storage |
- Store in a cool dry place.
|
| General Statements |
- - Do not exceed recommended dose.
- Do not purchase if foil is broken or damaged.
- SAMe has multiple mechanisms of action that are used throughout the body
- Brain and Mood
SAMe boosts brain cell methylation and facilitates youthful DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters such as norepinephrine, dopamine, and seratonin and may account for SAMe’s mood-elevating properties. SAMe also helps maintain acetylcholine levels which are necessary for cognitive function.
- Liver and Detox
In order to perform its detoxification role, the liver continually performs large numbers of complex enzymatic reactions. SAMe facilitates healthy methylation enzymatic processes and boosts hepatic levels of glutathione, a critical antioxidant.
- Joint SAMe may help to ease inflammation and can support healthy joint mobility and function without side effects.
- Supports joints and emotional well-being
- To report a serious adverse event or obtain product information, contact 1-866-280-2852
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| Formula |
- S-Adenosyl-Methionine
|
| FDA Statement of Identity |
- Dietary Supplement
|
| General |
- QE01934B
|
Brand Information
See all products by this brand
| Manufactured for: | |
|---|---|
| Name | Quality Supplements and Vitamins, Inc. |
| City | Ft. Lauderdale |
| State | FL |
| ZipCode | 33309 |
| Phone Number | 1-866-280-2852 |
| Web Address | LifeExtension.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.